Ilenia Adornato

An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications.

G. Wolber, P. Paoli, A. Del Corso, 2018, Bioorganic & medicinal chemistry letters.

In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B

T. Nguyen, G. Wolber, P. Paoli, 2021, Molecules.

Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects

A. Fais, F. Pintus, S. Vittorio, 2021, ChemMedChem.

Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease

S. Ventura, S. Vittorio, R. Gitto, 2020, Journal of enzyme inhibition and medicinal chemistry.

Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents.

V. Cardile, P. Paoli, A. Rotondo, 2017, European journal of medicinal chemistry.

Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B.

P. Paoli, R. Maccari, R. Ottanà, 2019, Bioorganic chemistry.

Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors.

A. Bitto, R. Maccari, R. Ottanà, 2017, Bioorganic & medicinal chemistry letters.

In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules

E. Russo, S. Vittorio, R. Gitto, 2021, Molecules.