Jungsu Kim

发表

Tutorial on Drug Development for Central Nervous

Hyejin Yoon, Jungsu Kim, 2010 .

Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia

A. Remaley, J. Witztum, Longhou Fang, 2015, Disease Models & Mechanisms.

APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice

D. Holtzman, M. Sadowski, P. Sullivan, 2017, Molecular Neurodegeneration.

Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages

E. Dennis, Soo-Ho Choi, D. Dumlao, 2013, PloS one.

Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish[S]

Yury I. Miller, A. Kamaid, J. Pattison, 2017, Journal of Lipid Research.

Anticancer effects of the MHY 218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells

Jee H Jung, H. Moon, Hyung Sik Kim, 2022 .

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply

T. Rana, A. Remaley, D. Traver, 2018, Nature Communications.

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL

Soo-Ho Choi, J. Witztum, Yury I. Miller, 2015, Autophagy.

Inhibition of Neuroinflammation by AIBP: Spinal Effects upon Facilitated Pain States.

H. Low, D. Sviridov, Soo-Ho Choi, 2018, Cell reports.

Synthesis of Neplanocin A Analog with 2′-“up”-C-Methyl Substituent as Potential Anti-HCV Agent

Boeun Lee, H. Moon, L. Jeong, 2009 .

Spleen Tyrosine Kinase Regulates AP-1 Dependent Transcriptional Response to Minimally Oxidized LDL

Soo-Ho Choi, Yury I. Miller, F. Almazan, 2012, PloS one.

Efficient and practical synthesis of L-hamamelose.

Boeun Lee, H. Moon, L. Jeong, 2009, Carbohydrate research.

MD-2 binds cholesterol.

Soo-Ho Choi, Yury I. Miller, S. Viriyakosol, 2016, Biochemical and biophysical research communications.

Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease

Raymond Scott Turner, M. Jung, Hyejin Yoon, 2013, Experimental Neurology.

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease*

E. Weeber, S. Estus, G. Bu, 2012, The Journal of Biological Chemistry.

Design, Synthesis, Antitumor Activity and Mode of Action of Novel Oxiranyl and Thiiranyl Phenol Derivatives.

H. Moon, L. Jeong, Hyung Sik Kim, 2009 .

First synthesis of 2′-oxabicyclo[3.1.0]hexyl nucleosides with a north conformation

H. Moon, L. Jeong, Chong-kyo Lee, 2010 .

Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages.

Soo-Ho Choi, Elena Alekseeva, S. Tsimikas, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Tubular human brain organoids to model microglia-mediated neuroinflammation.

K. Mackie, Zhuhao Wu, H. Cai, 2021, Lab on a chip.

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain

K. Ley, Soo-Ho Choi, I. Kufareva, 2021, The Journal of experimental medicine.

Single-cell resolution analysis of the crosstalk between chemogenically activated astrocytes and microglia

Y. Moon, M. Turnbull, Jungsu Kim, 2020, bioRxiv.

Aβ40 Inhibits Amyloid Deposition In Vivo

D. Dickson, T. Golde, C. Zwizinski, 2007, The Journal of Neuroscience.

Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis

Daniel C Smith, G. Viana di Prisco, A. Oblak, 2021, Science advances.

Analysis of Extracellular RNA by Digital PCR

T. Patel, Kenji Takahashi, I. Yan, 2014, Front. Oncol..

Network analysis reveals strain-dependent response to misfolded tau aggregates

B. Lamb, H. S. Wijeratne, C. Lasagna-Reeves, 2023, bioRxiv.

In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

D. Holtzman, R. Bateman, C. Xiong, 2012, PloS one.

AIBP protects retinal ganglion cells against neuroinflammation and mitochondrial dysfunction in glaucomatous neurodegeneration

Mark Ellisman, G. Perkins, R. Weinreb, 2020, Redox biology.

Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.

D. Holtzman, S. Paul, C. Wellington, 2008, The Journal of clinical investigation.

Blocking the Interaction between Apolipoprotein E and Ab Reduces Intraneuronal Accumulation of Ab and Inhibits

D. Holtzman, A. Asuni, M. Sadowski, 2013 .

Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer's disease.

D. Holtzman, K. Dikranian, F. Stewart, 2012, International journal of clinical and experimental pathology.

Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.

L. Goldstein, C. Lillo, David S. Williams, 2008, Human molecular genetics.

AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation.

Soo-Ho Choi, Elena Alekseeva, Longhou Fang, 2018, JCI insight.

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

D. Holtzman, R. Bateman, C. Xiong, 2012, PLoS ONE.

AIBP protects against metabolic abnormalities and atherosclerosis[S]

Dorothy D. Sears, Soo-Ho Choi, D. Sears, 2018, Journal of Lipid Research.

The Roles of GxxxG Motif and Gamma-Secretase Components in APP Processing

Jungsu Kim, 2009 .

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply

T. Rana, A. Remaley, D. Traver, 2018, Nature Communications.

The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis

P. Tontonoz, Jaekwang Kim, Cynthia Hong, 2015, Science Translational Medicine.

Synthesis of Novel N-(2-Hydroxyphenyl)arylsulfonamides as Selective HDAC Inhibitory and Cytotoxic Agents

H. Moon, P. Chun, Jungsu Kim, 2013 .

Prion-Like Behavior of Amyloid-β

D. Holtzman, Jungsu Kim, 2010, Science.

The E 3 ubiquitin ligase Idol controls brain LDL receptor expression , ApoE clearance , and A b amyloidosis

P. Tontonoz, Jaekwang Kim, Cynthia Hong, 2015 .

The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Ab amyloidosis

P. Tontonoz, Jaekwang Kim, Cynthia Hong, 2015 .

Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice

D. Holtzman, A. Asuni, M. Sadowski, 2014, Acta Neuropathologica Communications.

β Peptide Clearance

A. Fagan, D. Holtzman, S. Paul, 2011 .

Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.

L. Goldstein, C. Lillo, David S. Williams, 2008, Human molecular genetics.

Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease

Raymond Scott Turner, M. Jung, Hyejin Yoon, 2013, Experimental Neurology.

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL

Soo-Ho Choi, J. Witztum, Yury I. Miller, 2015, Autophagy.

Anticancer effects of the MHY218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells.

Jee H Jung, H. Moon, Hyung Sik Kim, 2010, International journal of oncology.

Synthesis and Importance of Bulky Aromatic Cap of Novel SAHA Analogs for HDAC Inhibition and Anticancer Activity

H. Moon, Jiyoung Park, Hyung Sik Kim, 2011 .