C. Shih

发表

Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.

C. Cywin, E. Hickey, M. Kashem, 2010, Journal of medicinal chemistry.

Nonnucleoside inhibitors of HIV-1 reverse transcriptase: nevirapine as a prototype drug.

P. Grob, R. Ingraham, J. Wu, 1992, AIDS research and human retroviruses.

Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.

C. Cywin, E. Hickey, M. Kashem, 2010, Bioorganic & medicinal chemistry letters.

A dominant trifluoperazine resistance gene from Saccharomyces cerevisiae has homology with F0F1 ATP synthase and confers calcium-sensitive growth

S. Feinstein, N. Neff, C. Kanik-Ennulat, 1988, Molecular and cellular biology.

Expression of a proteolipid gene from a high-copy-number plasmid confers trifluoperazine resistance to Saccharomyces cerevisiae

N. Neff, E. Montalvo, C. Shih, 1990, Molecular and cellular biology.

Selective inhibition of human cyclo-oxygenase-2 by meloxicam

L. Churchill, A. G. Graham, P. Grob, 1996, InflammoPharmacology.

Nucleotide sequence 5' of the chicken c-myc coding region: localization of a noncoding exon that is absent from myc transcripts in most avian leukosis virus-induced lymphomas.

W. S. Hayward, M. Goodenow, M. Linial, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Chimeric human immunodeficiency virus type 1/type 2 reverse transcriptases display reversed sensitivity to nonnucleoside analog inhibitors.

A. Bacolla, J. Wu, C. Shih, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones.

P. Grob, T. A. Kelly, D. Mcneil, 1997, Journal of medicinal chemistry.

Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand.

G. Nabozny, Ljiljana Žuvela-Jelaska, D. Kuzmich, 2005, Bioorganic & medicinal chemistry letters.

Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor.

J. Adams, K. Grozinger, J. Wu, 1990, Science.

Discovery of Imigliptin, a Novel Selective DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.

Jun Xu, H. Ge, P. Peng, 2014, ACS medicinal chemistry letters.

Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 8. 8-Aryloxymethyl- and 8-arylthiomethyldipyridodiazepinones.

C. Cywin, P. Grob, K. Barringer, 1998, Journal of medicinal chemistry.

Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture.

D. Richman, S. Goff, I. Lowy, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli

Y. Zhu, T. North, C. Shih, 1994, Antimicrobial Agents and Chemotherapy.

Comparative purification of recombinant HIV-1 and HIV-2 reverse transcriptase: preparation of heterodimeric enzyme devoid of unprocessed gene product.

S. Rogers, R. Ingraham, G. Caviness, 1992, Protein expression and purification.

Prophylaxis against HIV-1 infection in chimpanzees by nevirapine, a nonnucleoside inhibitor of reverse transcriptase

D. Ho, P. Grob, J. Adams, 1997, Nature Medicine.

Identification of dissociated non-steroidal glucocorticoid receptor agonists.

J. Proudfoot, P. Reilly, Alison J Kukulka, 2007, Bioorganic & medicinal chemistry letters.

Amino acid substitutions in HIV-1 reverse transcriptase with corresponding residues from HIV-2. Effect on kinetic constants and inhibition by non-nucleoside analogs.

D. Richman, A. Bacolla, R. Ingraham, 1993, The Journal of biological chemistry.

Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 7. 8-Arylethyldipyridodiazepinones as potent broad-spectrum inhibitors of wild-type and mutant enzymes.

C. Cywin, P. Grob, K. Barringer, 1998, Journal of medicinal chemistry.