E. Young

发表

Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.

C. Cywin, E. Hickey, M. Kashem, 2010, Journal of medicinal chemistry.

Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.

C. Cywin, E. Hickey, M. Kashem, 2010, Bioorganic & medicinal chemistry letters.

Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.

M. Hao, D. White, K. Crane, 2007, Bioorganic & medicinal chemistry letters.

Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells*

P. Cohen, H. Choi, M. Peggie, 2012, The Journal of Biological Chemistry.

Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement.

E. Hickey, N. Moss, Yancey D. Ward, 2012, Bioorganic & medicinal chemistry letters.

A Practical Synthesis of Pyrene-4,5-dione.

R. L. Funk, E. Young, 1999 .

A Practical Synthesis of Pyrene-4,5-dione

R. L. Funk, E. Young, 1998 .

Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.

Xiang Li, Eugene R. Hickey, Steven Kerr, 2010, Bioorganic & medicinal chemistry letters.

Photochemical Cycloaromatization Reactions of ortho-Dialkynylarenes: A New Class of DNA Photocleaving Agents

R. L. Funk, Robin M. Williams, E. Young, 1996 .

Novel cross-talk within the IKK family controls innate immunity.

P. Cohen, J. Madwed, M. Peggie, 2011, The Biochemical journal.

Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration.

B. Muegge, B. Cummings, Qiuhe Lu, 2018, Cell host & microbe.

BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression.

Harald J. Maier, H. Pehamberger, J. Madwed, 2010, Genes & cancer.

Discovery of potent and selective PKC-θ inhibitors

Mario G. Cardozo, Mohammed A. Kashem, Carol Ann Homon, 2007 .

Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.

Xiang Li, C. Cywin, E. Hickey, 2010, Bioorganic & medicinal chemistry letters.

Detection of PTF10cwr/CSS100313 on PS1 sky survey images and host galaxy identification

W. M. Wood-Vasey, R. Kotak, S. Smartt, 2010 .

Discovery of potent and selective PKC-theta inhibitors.

Mohammed A Kashem, C. Homon, J. Woska, 2007, Bioorganic & medicinal chemistry letters.

CHAPTER 9:IKKβ as a Therapeutic Intervention Point for Diseases Related to Inflammation

E. Young, 2012 .