Dorota D. Klysz

发表

Enhanced safety and efficacy of protease-regulated CAR-T cell receptors

Howard Y. Chang, Ansuman T. Satpathy, Louai Labanieh, 2022, Cell.

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors

Louai Labanieh, Ovijit Chaudhuri, J. Cochran, 2021, bioRxiv.

Enhanced Effector Activity of Mediator Kinase Module Deficient CAR-T Cells

Howard Y. Chang, Ansuman T. Satpathy, J. Espinosa, 2022, bioRxiv.

Enhanced T cell effector activity by targeting the Mediator kinase module

Howard Y. Chang, Ansuman T. Satpathy, J. Espinosa, 2022, Science.

Title: Enhanced Effector Activity of Mediator Kinase Module Deficient CAR-T Cells

Ansuman T. Satpathy, J. Espinosa, E. Sotillo, 2022 .

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.

Howard Y. Chang, Ansuman T. Satpathy, D. Dimitrov, 2021, Cancer cell.

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

Philippe A. Robert, Marco Craveiro, N. Taylor, 2015, Science Signaling.

Transient “rest” restores functionality in exhausted CAR-T cells via epigenetic remodeling

Howard Y. Chang, Ansuman T. Satpathy, A. Gentles, 2021, Science.

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification.

Marco Craveiro, M. Sitbon, N. Taylor, 2014, Cell stem cell.

Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

Mark M. Davis, P. A. Futreal, I. Weissman, 2021, Immunity.

Co-opting signalling molecules enables logic-gated control of CAR T cells

Ansuman T. Satpathy, C. Lareau, Louai Labanieh, 2023, Nature.

Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

A. Dunn, Louai Labanieh, C. Mackall, 2022, bioRxiv.

PET Reporter Gene Imaging and Ganciclovir-Mediated Ablation of Chimeric Antigen Receptor T Cells in Solid Tumors

S. Gambhir, Louai Labanieh, Amin Aalipour, 2020, Cancer Research.

Inosine Induces Stemness Features in CAR T cells and Enhances Potency

Ansuman T. Satpathy, K. Davis, Louai Labanieh, 2023, bioRxiv.

A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells

E. Sotillo, Victor Tieu, Dorota D. Klysz, 2024, Cell.

FOXO1 is a master regulator of memory programming in CAR T cells

E. Sotillo, Dorota D. Klysz, Peng Xu, 2024, Nature.

Sequential intravenous and intracerebroventricular GD2-CAR T-cell therapy for H3K27M-mutated diffuse midline gliomas

Snehit Prabhu, B. Sahaf, S. Partap, 2024, medRxiv.

Inosine induces stemness features in CAR-T cells and enhances potency.

Louai Labanieh, E. Sotillo, A. Leruste, 2024, Cancer cell.