L. Capone

发表

Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity

E. Hur, J. Kosek, P. Schafer, 2017, The Journal of Immunology.

Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

Lei Wu, G. Baillie, M. Houslay, 2010, British Journal of Pharmacology.

Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration

J. Kosek, S. Surapaneni, P. Schafer, 2012, Cancer Chemotherapy and Pharmacology.

Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study

E. Hur, J. Kosek, A. Kivitz, 2019, Rheumatology and Therapy.

Dexamethasone synergizes with lenalidomide to inhibit multiple myeloma tumor growth, but reduces lenalidomide-induced immunomodulation of T and NK cell function.

L. Sapinoso, G. Hampton, T. Tran, 2010, Current cancer drug targets.

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.

Jilly F. Evans, R. Chopra, P. Schafer, 2014, Cellular signalling.

CC-122 Is a Novel Pleiotropic Pathway Modifier with Potent in Vitro Immunomodulatory and Anti-Angiogenic Properties and in Vivo Anti-Tumor Activity in Hematological Cancers.

R. Chopra, Lei Wu, J. Kosek, 2012 .

Disposition, metabolism and mass balance of [14C]apremilast following oral administration

S. Surapaneni, P. Schafer, O. Laskin, 2011, Xenobiotica; the fate of foreign compounds in biological systems.

Isosteric analogs of lenalidomide and pomalidomide: synthesis and biological activity.

P. Schafer, Alexander L. Ruchelman, L. Corral, 2013, Bioorganic & medicinal chemistry letters.

Dexamethasone Synergizes with Lenalidomide to Inhibit Multiple Myeloma Tumor Growth, But Reduces Lenalidomide-Induced Immunomodulation of T and NK Cell Function

T. Tran, L. Sapinoso, G. Hampton, 2010 .

Opposing Effects of Dexamethasone on Lenalidomide Activity in Multiple Myeloma: Additive/Synergistic Effects on Anti-Proliferative Activity on Myeloma Cells and Antagonistic Effects on Immune Function

Lei Wu, P. Schafer, A. Gandhi, 2008 .

Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

Lei Wu, G. Baillie, P. Schafer, 2010, British journal of pharmacology.

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.

Jilly F. Evans, R. Chopra, P. Schafer, 2014, Cellular signalling.