Le Zhao

发表

Downregulation of DNMT3A Attenuates the Warburg Effect, Proliferation, and Invasion via Promoting the Inhibition of miR-603 on HK2 in Ovarian Cancer

Yuanyuan Zhou, Xu Li, Wei Chen, 2022, Technology in cancer research & treatment.

Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway.

Lu Ding, Xu Li, Wei Chen, 2014, International journal of molecular medicine.

Defensins in innate immunity

Wuyuan Lu, Le Zhao, 2014, Current opinion in hematology.

Carfilzomib inhibits cell cycle progression at G 2 / M phase and induces apoptosis in breast cancer cells

Ke Wang, Yuanyuan Zhou, Yuanyi You, 2016 .

Total chemical synthesis of dengue 2 virus capsid protein via native chemical ligation: role of the conserved salt-bridge.

Weiyue Lu, Wuyuan Lu, C. Zhan, 2013, Bioorganic & medicinal chemistry.

Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer

L. Hua, Xu Li, Wei Chen, 2016, Oncotarget.

Ginsenoside 20(S)-Rg3 induced autophagy to inhibit migration and invasion of ovarian cancer.

Xu Li, Wei Chen, Hui-jin Li, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Cortactin is associated with tumour progression and poor prognosis in prostate cancer and SIRT2 other than HADC6 may work as facilitator in situ

Yili Wang, Guanjun Zhang, Xu Li, 2012, Journal of Clinical Pathology.

TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

Xu Li, Wei Chen, Lijie Wang, 2016, Journal of experimental & clinical cancer research : CR.

UCA1, a non‐protein‐coding RNA up‐regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion

Xu Li, Wei Chen, Fan Wang, 2008, FEBS letters.

Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells.

Chen Yang, Xu Li, Wei Chen, 2012, Gene.

20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer.

Xu Li, Wei Chen, Zhongxue Ye, 2017, Oncotarget.

miR-30d Blocked Transforming Growth Factor β1–Induced Epithelial-Mesenchymal Transition by Targeting Snail in Ovarian Cancer Cells

J. Li, Wei Chen, Zhongxue Ye, 2015, International Journal of Gynecologic Cancer.

Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a

Li-rui Zhang, Chen Li, Yuanyuan Zhou, 2015, International journal of molecular medicine.

In Vitro and In Vivo Synergistic Therapeutic Effect of Cisplatin with Human Papillomavirus16 E6/E7 CRISPR/Cas9 on Cervical Cancer Cell Line

Xu Li, Lijie Wang, Shuai Zhen, 2016, Translational oncology.

LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway.

K. Taylor, Xu Li, Wei Chen, 2007, Biochemical and biophysical research communications.

An ultrahigh affinity d-peptide antagonist Of MDM2.

M. Pazgier, Weirong Yuan, Weiyue Lu, 2012, Journal of medicinal chemistry.

Interrogation of MDM2 phosphorylation in p53 activation using native chemical ligation: the functional role of Ser17 phosphorylation in MDM2 reexamined.

Weirong Yuan, Wuyuan Lu, C. Zhan, 2012, Journal of the American Chemical Society.

D‐Peptide‐Based Drug Discovery Aided by Chemical Protein Synthesis

Wuyuan Lu, Le Zhao, 2011 .

A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells

J. Li, Xu Li, Wei Chen, 2017, Cellular Physiology and Biochemistry.

Id-1, a Protein Repressed by miR-29b, Facilitates the TGFβ1-Induced Epithelial-Mesenchymal Transition in Human Ovarian Cancer Cells

Wei Chen, Yan Zhang, Y. Teng, 2014, Cellular Physiology and Biochemistry.

Ginsenoside 20(S)-Rg3 Targets HIF-1α to Block Hypoxia-Induced Epithelial-Mesenchymal Transition in Ovarian Cancer Cells

Lu Ding, Dan Liu, Xu Li, 2014, PloS one.

Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2013, PloS one.

Mirror image proteins.

Le Zhao, Wuyuan Lu, Wuyuan Lu, 2014, Current opinion in chemical biology.

Synergistic Antitumor Effect on Bladder Cancer by Rational Combination of Programmed Cell Death 1 Blockade and CRISPR-Cas9-Mediated Long Non-Coding RNA Urothelial Carcinoma Associated 1 Knockout.

Xu Li, Wei Chen, Shuai Zhen, 2018, Human gene therapy.

Hsp74, a Potential Bladder Cancer Marker, Has Direct Interaction with Keratin 1

Xinhan Zhao, Yarong Wang, Xu Li, 2014, Journal of immunology research.

H19 promotes endometrial cancer progression by modulating epithelial-mesenchymal transition.

Huan Pang, Xu Li, Wei Chen, 2017, Oncology letters.

H 19 promotes endometrial cancer progression by modulating epithelial-mesenchymal transition

Huan Pang, Li Xu, Wei Chen, 2016 .

Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interaction.

Chong Li, Weiyue Lu, Wuyuan Lu, 2013, Bioorganic & medicinal chemistry.

Epithelial-mesenchymal transition (EMT) is a key mechanism facilitating cancer metastasis. Targeting the EMT process with more efficacious and less toxic agents to prevent metastasis is of significant therapeutic value for ovarian cancer treatment. The anti-EMT function and mechanism of ginsenoside

Y. Teng, Xu Li, Wei Chen, 2017 .

Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.

Langchong He, Jing Zhao, Xu Li, 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

miR-532-3p suppresses proliferation and invasion of ovarian cancer cells via GPNMB/HIF-1α/HK2 axis.

Yuanyuan Zhou, Ruiqi Wang, Xiling Yang, 2022, Pathology, research and practice.

Ginsenoside 20(S)-Rg3 Inhibits the Warburg Effect Via Modulating DNMT3A/ MiR-532-3p/HK2 Pathway in Ovarian Cancer Cells

Yuanyuan Zhou, Xu Li, Wei Chen, 2018, Cellular Physiology and Biochemistry.

Vascular endothelial growth factor receptor 2 (VEGFR2, Flk‐1/KDR) protects HEK293 cells against CoCl2‐induced hypoxic toxicity

Langchong He, Xu Li, Wei Chen, 2012, Cell biochemistry and function.

TET1 promotes cisplatin‐resistance via demethylating the vimentin promoter in ovarian cancer

Yuanyuan Zhou, Xu Li, Wei Chen, 2017, Cell biology international.

HDAC6 and SIRT2 promote bladder cancer cell migration and invasion by targeting cortactin.

Wenjing Wu, Xu Li, Wei Chen, 2011, Oncology reports.

Immunoscreening of urinary bladder cancer cDNA library and identification of potential tumor antigen

Xu Li, Haiyun Yu, Wei Chen, 2009, World Journal of Urology.

Ginsenoside 20(S)-Rg3 Prevents PKM2-Targeting miR-324-5p from H19 Sponging to Antagonize the Warburg Effect in Ovarian Cancer Cells

Yuanyuan Zhou, Xu Li, Wei Chen, 2018, Cellular Physiology and Biochemistry.

miR-210, a modulator of hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cell.

Lu Ding, Xu Li, Wei Chen, 2015, International journal of clinical and experimental medicine.

Ginsenoside 20(S)-Rg3 suppresses ovarian cancer migration via hypoxia-inducible factor 1 alpha and nuclear factor-kappa B signals

Lu Ding, Xu Li, Wei Chen, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Ginsenoside 20(S)‑Rg3 inhibits the Warburg effect through STAT3 pathways in ovarian cancer cells.

Xu Li, Wei Chen, Zhongxue Ye, 2015, International journal of oncology.

Ginsenoside 20(S)‐Rg3 upregulates HIF‐1α‐targeting miR‐519a‐5p to inhibit the Warburg effect in ovarian cancer cells

Hong Chen, Xu Li, Wei Chen, 2020, Clinical and experimental pharmacology & physiology.

Functional Determinants of Human Enteric α-Defensin HD5

M. Pazgier, Wuyuan Lu, E. D. de Leeuw, 2012, The Journal of Biological Chemistry.

Systematic mutational analysis of human neutrophil α-defensin HNP4.

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2019, Biochimica et biophysica acta. Biomembranes.

Invariant Gly Residue Is Important for α-Defensin Folding, Dimerization, and Function

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2012, The Journal of Biological Chemistry.

[Genetic polymorphism analysis of 3 short tandem repeat loci on chromosome 21 in Chinese Han population in Shaanxi Province].

Xu Li, Xiang Wang, Wei Chen, 2008, Nan fang yi ke da xue xue bao = Journal of Southern Medical University.

Expression and significance of cortactin and HDAC6 in human prostatic foamy gland carcinoma

Guanjun Zhang, Xu Li, Jing Li, 2015, International journal of experimental pathology.

miR-603 targeted hexokinase-2 to inhibit the malignancy of ovarian cancer cells.

Hong Chen, Yuanyuan Zhou, Yue-ling Wang, 2019, Archives of biochemistry and biophysics.

TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

Xu Li, Wei Chen, Lijie Wang, 2016, Journal of Experimental & Clinical Cancer Research.

Id-1, a Protein Repressed by miR-29b, Facilitates the TGFβ1-Induced Epithelial-Mesenchymal Transition in Human Ovarian Cancer Cells

Wei Chen, Yan Zhang, Xu Li, 2014, Cellular Physiology and Biochemistry.

Id-1, a Protein Repressed by miR-29b, Facilitates the TGFβ1-Induced Epithelial-Mesenchymal Transition in Human Ovarian Cancer Cells

Wei Chen, Yan Zhang, Xu Li, 2014, Cellular Physiology and Biochemistry.

20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.

Hong Chen, Yuanyuan Zhou, Mei Xue, 2020, Archives of biochemistry and biophysics.

The negative feedback between miR‐143 and DNMT3A regulates cisplatin resistance in ovarian cancer

Li-rui Zhang, Yuanyuan Zhou, Xu Li, 2020, Cell biology international.

[Ginsenoside 20(S)-Rg3 upregulates tumor suppressor VHL gene expression by suppressing DNMT3A-mediated promoter methylation in ovarian cancer cells].

Yuanyuan Zhou, Xu Li, Wei Chen, 2021, Nan fang yi ke da xue xue bao = Journal of Southern Medical University.