Wenfeng Gou

发表

Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction

Hongying Wu, Huiqiang Wei, Hongxin Ning, 2022, International journal of biological sciences.

CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.

X. Zhai, Daiying Zuo, Zi Liu, 2018, Cancer letters.

Novel PHD2/HDACs hybrid inhibitors protect against cisplatin-induced acute kidney injury.

Huiqiang Wei, Hongxin Ning, Yiliang Li, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel 4-anilinoquinazoline derivatives as hypoxia-selective EGFR and VEGFR-2 dual inhibitors.

Yong Qin, Yuqing Duan, Huiqiang Wei, 2019, European journal of medicinal chemistry.

Recent progress in small-molecule inhibitors for critical therapeutic targets of necroptosis.

Leyuan Chen, Huiqiang Wei, Changfen Bi, 2021, Future medicinal chemistry.

Molecular mechanisms of isoflavone puerarin against cardiovascular diseases: What we know and where we go

Wenfeng Gou, Jianghong Guo, Wenbin Hou, 2022, Chinese herbal medicines.

Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca2+ Imbalance-Mediated Endoplasmic Reticulum Stress

Daiying Zuo, Zi Liu, Xuejiao Zhou, 2019, Oxidative medicine and cellular longevity.

Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress.

Daiying Zuo, Xuejiao Zhou, Zengqiang Li, 2018, Environmental toxicology and pharmacology.

Discovery of the radio-protecting effect of Ecliptae Herba, its constituents and targeting p53-mediated apoptosis in vitro and invivo

Zhiyun Wang, Changxiao Liu, Deguan Li, 2022, Acta pharmaceutica Sinica. B.

Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors

Tiemin Sun, Yiliang Li, Yating Cui, 2022, Journal of enzyme inhibition and medicinal chemistry.

Identification of potent SENP1 inhibitors that inactivate SENP1/JAK2/STAT signaling pathway and overcome platinum drug resistance in ovarian cancer

Wei Zheng, Wenge Zhu, Yunxiao Meng, 2021, Clinical and translational medicine.

Phosphate group functionalized magnetic metal–organic framework nanocomposite for highly efficient removal of U(VI) from aqueous solution

Langxing Chen, Ye Yuan, Hongxin Ning, 2021, Scientific Reports.

Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure-Activity Relationship Study.

Huiqiang Wei, Hongxin Ning, Yiliang Li, 2022, Journal of natural products.

Discovery and radiosensitization research of ursolic acid derivatives as SENP1 inhibitors.

Huiqiang Wei, Hongxin Ning, Yiliang Li, 2021, European journal of medicinal chemistry.

ZX-29, a novel ALK inhibitor, induces apoptosis via ER stress in ALK rearrangement NSCLC cells and overcomes cell resistance caused by an ALK mutation.

X. Zhai, Daiying Zuo, Xuejiao Zhou, 2020, Biochimica et biophysica acta. Molecular cell research.

Discovery and characterization of potent And‐1 inhibitors for cancer treatment

Ruili Huang, M. Xia, Wei Zheng, 2021, Clinical and translational medicine.

Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma

Shuo Chen, Yang Zhao, Y. Takano, 2013, Tumor Biology.

Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives.

X. Zhai, Junlong Zhang, Nan Jiang, 2018, European journal of medicinal chemistry.

2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines

Daiying Zuo, Zengqiang Li, Yingliang Wu, 2018, Cancer biology & therapy.

Structure-based design, synthesis, and evaluation of inhibitors with high selectivity for PARP-1 over PARP-2.

Tiemin Sun, Yiliang Li, Yating Cui, 2021, European journal of medicinal chemistry.

Response of resource allocation of Saussurea leontodontoides during its fruiting stage to the elevation

Lei Li, Yi-Feng Wang, Wenfeng Gou, 2020, Chinese Journal of Plant Ecology.

Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R.

X. Zhai, Yucheng Gu, Daiying Zuo, 2018, European journal of medicinal chemistry.

Discovery of novel triazole compounds as selective IL-1β releasement inhibitors.

Lei Zhu, C. Ye, Leyuan Chen, 2021, Bioorganic & medicinal chemistry letters.

Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer.

Hongying Wu, Daiying Zuo, Yingliang Wu, 2022, Cancer letters.

Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress

Na Luo, Hongying Wu, Yuqing Duan, 2020, Pharmaceutical biology.

Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.

Hongxin Ning, Yiliang Li, Wenfeng Gou, 2023, Journal of ethnopharmacology.

PET imaging of new target CDK19 in prostate cancer.

Ting Huang, Saijun Fan, Dong Dai, 2023, European journal of nuclear medicine and molecular imaging.

Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation

S. Jiao, Daiying Zuo, Yiliang Li, 2022, Frontiers in Pharmacology.