Chun-Lin Chen

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The Antileukemic and Anti-Prostatic Effect of Aeroplysinin-1 Is Mediated through ROS-Induced Apoptosis via NOX Activation and Inhibition of HIF-1a Activity

M. El‐Shazly, S. Shih, Yu-Hsuan Lin, 2022, Life.

Targeting SYK kinase‐dependent anti‐apoptotic resistance pathway in B‐lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic

F. Uckun, S. Qazi, Rauf Ek, 2010, British journal of haematology.

Clinical Pharmacokinetics of the CD19 Receptor‐Directed Tyrosine Kinase Inhibitor B43‐Genistein in Patients with B‐Lineage Lymphoid Malignancies

F. Uckun, A. Levine, F. Goldman, 1999, Journal of clinical pharmacology.

In Vivo Pharmacokinetic Features, Toxicity Profile, and Chemosensitizing Activity of α-Cyano-β-hydroxy-β- methyl-N-(2,5-dibromophenyl)propenamide (LFM-A13), a Novel Antileukemic Agent Targeting Bruton’s Tyrosine Kinase

F. Uckun, A. Vassilev, B. Waurzyniak, 2002 .

Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation.

Chi‐Huey Wong, Chung-Yi Wu, Jim-Min Fang, 2013, Angewandte Chemie.

CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation.

F. Uckun, E. Sudbeck, C. Mao, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors.

Chi‐Huey Wong, K. Tsai, Jim-Min Fang, 2014, Bioorganic & medicinal chemistry.

Tamiphosphor monoesters as effective anti-influenza agents.

Chi‐Huey Wong, J. Jan, K. Tsai, 2014, European journal of medicinal chemistry.

Development of oseltamivir phosphonate congeners as anti-influenza agents.

Chi‐Huey Wong, J. Jan, Jim-Min Fang, 2012, Journal of medicinal chemistry.

HEMATOLOGIC AND SERUM BIOCHEMICAL PARAMETERS OF APPARENTLY HEALTHY RESCUED FORMOSAN PANGOLINS (MANIS PENTADACTYLA PENTADACTYLA)

S. Chin, L. Yeh, Chun-Lin Chen, 2015, Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.

In Vivo Toxicity, Pharmacokinetics, and Anti-Human Immunodeficiency Virus Activity of Stavudine-5′-(p-Bromophenyl Methoxyalaninyl Phosphate) (Stampidine) in Mice

F. Uckun, S. Pendergrass, B. Waurzyniak, 2002, Antimicrobial Agents and Chemotherapy.

Bioavailabilty and pharmacokinetics of four active alkaloids of traditional Chinese medicine Yanhuanglian in rats following intravenous and oral administration.

Huiliang Li, Wei-Dong Zhang, Chuan Zhang, 2006, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of four active alkaloids from a traditional Chinese medicine Corydalis saxicola Bunting. (Yanhuanglian) in plasma and urine samples by LC-MS-MS.

Ting Han, Chuan Zhang, T. Han, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Toxicity and Pharmacokinetics of Stampidine in Mice and Rats

F. Uckun, B. Waurzyniak, T. Venkatachalam, 2003, Arzneimittelforschung.

In Vivo Antiretroviral Activity of Stampidine in Chronically Feline Immunodeficiency Virus-Infected Cats

F. Uckun, S. Pendergrass, B. Waurzyniak, 2003, Antimicrobial Agents and Chemotherapy.

ANTI-HUMAN IMMUNODEFICIENCY VIRUS AGENT D 4 T-5 *-[ P-BROMOPHENYL METHOXYALANINYL PHOSPHATE ] ( SAMPIDINE ) IN MICE

T. Venkatachalam, Zhaoling Zhu, Chun-Lin Chen, 2001 .

In vitro and in vivo Pharmacokinetic Features and Metabolism of the Novel Cytotoxic Nucleoside Analog 3’-Azidothymidine 5’- [p-Methoxyphenyl Methoxyalaninyl Phosphate] (Compound 003)

F. Uckun, T. Venkatachalam, I. Dibirdik, 2004, Arzneimittelforschung.

Metabolism of stavudine-5'-[p-bromophenyl methoxyalaninyl phosphate], stampidine, in mice, dogs, and cats.

F. Uckun, Gengli Yu, Chun-Lin Chen, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Quantitative determination of the anticancer agent tubeimoside I in rat plasma by liquid chromatography coupled with mass spectrometry.

Huiliang Li, Yun-Heng Shen, Wei-Dong Zhang, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs.

Wei-Dong Zhang, Run-Hui Liu, Hui-Liang Li, 2006, Life sciences.

Bioavailability and Pharmacokinetic Features of Etoposide in Childhood Acute Lymphoblastic Leukemia Patients

F. Uckun, J. Rawwas, A. Sorrell, 2001, Leukemia & lymphoma.

In Vivo Pharmacokinetics and Anti-Anaphylactic Activity of the Novel Mast Cell Inhibitor 4-(4´-Hydroxylphenyl)-Amino-6,7-Dimethoxyquinazoline (WHI-P131)

F. Uckun, R. Malaviya, Chun-Lin Chen, 2001, American journal of therapeutics.

Synthesis of Dual Function (5R,6R)- and (5S,6S)-5-Bromo-6-Methoxy-5,6-Dihydro-AZT-5′-(Para-Bromophenyl Methoxyalaninyl Phosphate) as Novel Spermicidal and Anti-HIV Agents

F. Uckun, Chun-Lin Chen, O. D’cruz, 1999, Antiviral chemistry & chemotherapy.

In vivo pharmacokinetic features, toxicity profile, and chemosensitizing activity of alpha-cyano-beta-hydroxy-beta- methyl-N-(2,5-dibromophenyl)propenamide (LFM-A13), a novel antileukemic agent targeting Bruton's tyrosine kinase.

F. Uckun, A. Vassilev, B. Waurzyniak, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90

M. El‐Shazly, K. Hsu, F. Kuo, 2021, Molecules.

Monitoring the gestation period of rescued Formosan pangolin (Manis pentadactyla pentadactyla) with progesterone radioimmunoassay.

S. Chin, L. Yeh, Chun-Lin Chen, 2012, Zoo biology.

Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosis-inducing CD19-directed tyrosine kinase inhibitor.

F. Uckun, A. Levine, F. Goldman, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Preliminary Acute and Subchronic Toxicity Studies of GLG-V-13, a Novel Class III Antiarrhythmic Agent, in Mice

R. Lazzara, B. Scherlag, K. Berlin, 2000, Arzneimittelforschung.

Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97).

X. P. Liu, F. Uckun, M. Keenan, 2000, The Journal of pharmacology and experimental therapeutics.

In vivo pharmacokinetics and metabolism of anti-human immunodeficiency virus agent D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] (SAMPIDINE) in mice.

F. Uckun, T. Venkatachalam, C. L. Chen, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacokinetic Features and Metabolism of Calphostin C, A Naturally Occurring Perylenequinone with Antileukemic Activity

F. Uckun, Chun-Lin Chen, De-Min Zhu, 1999, Pharmaceutical Research.

Tamiphosphor monoesters as effective anti-influenza agents.

Chi‐Huey Wong, J. Jan, K. Tsai, 2014, European journal of medicinal chemistry.

Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.

F. Uckun, F. Uckun, C. L. Chen, 1999, Molecular human reproduction.

In vivo toxicity and pharmacokinetic features of the janus kinase 3 inhibitor WHI-P131 [4-(4'hydroxyphenyl)-amino-6,7- dimethoxyquinazoline.

X. P. Liu, F. Uckun, C. L. Chen, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Zidampidine, an aryl phosphate derivative of AZT: in vivo pharmacokinetics, metabolism, toxicity, and anti-viral efficacy against hemorrhagic fever caused by Lassa virus.

F. Uckun, A. Vassilev, T. Venkatachalam, 2005, Bioorganic & medicinal chemistry.