Thomas Robert

发表

Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors.

B. Baratte, S. Ruchaud, Richard M. Beteck, 2021, Chemico-biological interactions.

Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

M. Dimanche-Boitrel, M. Rousselot, B. Baratte, 2021, Molecules.

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

B. Baratte, S. Ruchaud, N. Levoin, 2022, Molecules.

Streptomyces hygroscopicus UFPEDA 3370: A valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells.

C. Peixoto, B. Baratte, A. Wisniewski, 2020, Chemico-biological interactions.

From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3).

Carlos Roca, C. Pérez, Ana Martínez, 2019, Organic & biomolecular chemistry.

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors.

F. Gouilleux, P. Bonnet, S. Ruchaud, 2018, European journal of medicinal chemistry.

Thiazolo[5,4‐ f ]quinoxalines, Oxazolo[5,4‐ f ]quinoxalines and Pyrazino[ b,e ]isatins: Synthesis from 6‐Aminoquinoxalines and Properties

V. Dorcet, T. Roisnel, W. Erb, 2021, European Journal of Organic Chemistry.

Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2-a]pyridines derivatives as protein kinase inhibitors.

O. Lozach, B. Baratte, S. Ruchaud, 2016, European journal of medicinal chemistry.

2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities

S. Ruchaud, T. Roisnel, W. Erb, 2018 .

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

F. Gouilleux, Cécile Croix, M. Viaud-Massuard, 2021, Molecules.

From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

T. Roisnel, W. Erb, O. Mongin, 2023, New Journal of Chemistry.

Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

F. Gouilleux, B. Baratte, F. McCarthy, 2021, Molecules.

Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation

L. Corcos, C. Le Jossic-Corcos, B. Baratte, 2020 .

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

P. Le Pape, B. Baratte, N. Rachidi, 2020, European journal of medicinal chemistry.

Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

Jared L. Johnson, L. Cantley, P. Colas, 2020, Frontiers in Chemistry.

Synthesis and biological evaluation of selected 7H-pyrrolo[2,3-d]pyrimidine derivatives as novel CDK9/CyclinT and Haspin inhibitors.

B. Baratte, S. Ruchaud, Richard M. Beteck, 2021, Chemico-biological interactions.

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition.

Michael M. Cahill, S. Ruchaud, F. McCarthy, 2018, Bioorganic & medicinal chemistry.

Functional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders

P. Colas, A. Dock-Brégeon, Thomas Robert, 2021, Molecular genetics & genomic medicine.

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.

P. Colas, P. Bonnet, J. Bignon, 2020, European journal of medicinal chemistry.

Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: exploration of their effects against protein kinases and in silico ADME profiling

J. Bazureau, S. Bach, A. Bouattour, 2022, Journal of Molecular Structure.

Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells.

Khaled M. Elokely, S. Knapp, A. Chaikuad, 2023, Bioorganic chemistry.

Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening.

Sukanya, S. Filipek, S. Ruchaud, 2021, Bioorganic & medicinal chemistry letters.

Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies.

B. Baratte, R. Esmaeili, A. Foroumadi, 2023, Bioorganic chemistry.

Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts

F. Bussière, S. Lacroix-Lamandé, F. Laurent, 2023, Microbiology spectrum.

Tampering with Cell Division by Using Small‐Molecule Inhibitors of CDK–CKS Protein Interactions

Aurélien Lesnard, S. Rault, M. Miteva, 2015, Chembiochem : a European journal of chemical biology.