A. K. Greifenberg

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.

N. Hannett, R. Young, N. Gray, 2016, Nature chemical biology.

P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates

Jesse J. Lipp, K. Shokat, T. Rana, 2016, Genes & development.

CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer.

A. Richardson, J. Baselga, G. Shapiro, 2016, Cell reports.

Structural and Functional Analysis of the Cdk13/Cyclin K Complex.

M. Geyer, K. Anand, D. Blazek, 2016, Cell reports.

Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation

M. Geyer, C. A. Bösken, Friederike Itzen, 2014, Nucleic acids research.

Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.

M. Geyer, M. Eilers, E. Wolf, 2016, Molecular cell.

Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.

K. Stegmaier, N. Gray, S. Ficarro, 2021, European journal of medicinal chemistry.

MIR sequences recruit zinc finger protein ZNF768 to expressed genes

H. Blum, C. Friedel, D. Eick, 2018, Nucleic acids research.