Venkat R. Pallela

发表

Vasoactive Intestinal Peptide Receptor Agonist : Functional Studies

S. Rattan, M. Thakur, Venkat R. Pallela, 2006 .

Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agent.

E. Reddy, M. Reddy, Balaiah Akula, 2013, Organic & biomolecular chemistry.

Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblastic leukemia

E. Reddy, A. Aggarwal, S. Baker, 2018, Oncotarget.

Design, synthesis, and biological evaluation of (E)-styrylbenzylsulfones as novel anticancer agents.

E. Reddy, M. Reddy, S. Cosenza, 2008, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.

E. Reddy, J. Gabriel, R. Boominathan, 2008, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.

E. Reddy, J. Gallo, M. Reddy, 2013, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitors.

E. Reddy, R. Boominathan, M. Reddy, 2005, Bioorganic & medicinal chemistry.

(Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.

E. Reddy, M. Reddy, Balaiah Akula, 2012, Journal of medicinal chemistry.

Discovery of 8-Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinase 4 (CDK4) and AMPK-Related Kinase 5 (ARK5)

E. Reddy, S. Baker, M. Reddy, 2014, Journal of medicinal chemistry.

Design, synthesis and evaluation of (E)-alpha-benzylthio chalcones as novel inhibitors of BCR-ABL kinase.

E. Reddy, M. Truongcao, M V Ramana Reddy, 2010, Bioorganic & medicinal chemistry.

Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).

R. Jain, A. Aggarwal, Shashidhar S Jatiani, 2016, Bioorganic & medicinal chemistry.

Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2',4',6'-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity.

E. Reddy, M. Reddy, Balaiah Akula, 2011, Journal of medicinal chemistry.

(Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.

M. Reddy, Balaiah Akula, S. Cosenza, 2012, Journal of medicinal chemistry.