Kristine L. Yang

The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model.

Tianshu Yang, Yang Yu, Shayahati Bieerkehazhi, 2017, Cancer letters.

Bioreducible Pro-drug Inhibitors of Enolase

F. Muller, Dimitra K. Georgiou, Victoria C. Yan, 2020 .

Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma

Tianshu Yang, Yang Yu, Jiaxiong Lu, 2016, Oncotarget.

Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers

F. Muller, Dimitra K. Georgiou, Yu-Hsi Lin, 2022, Journal of medicinal chemistry.

Why Great Mitotic Inhibitors Make Poor Cancer Drugs.

F. Muller, C. Pham, Victoria C. Yan, 2020, Trends in cancer.

Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.

F. Muller, Dimitra K. Georgiou, C. Pham, 2020, ACS medicinal chemistry letters.

Aliphatic amines are viable pro-drug moieties in phosphonoamidate drugs.

F. Muller, C. Pham, Victoria C. Yan, 2020, Bioorganic & medicinal chemistry letters.