R. Knight

Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors

E. Sausville, P. LoRusso, M. Carducci, 2014, Cancer Chemotherapy and Pharmacology.

Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis

J. S. McKay, J. Yates, P. Newham, 2013, Inflammation Research.

Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?

A. Boobis, R. Roberts, M. Jacobsen, 2015, Regulatory toxicology and pharmacology : RTP.

Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat

F. Westwood, I. Wilson, E. Lenz, 2005, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Translational strategies for development of monoclonal antibodies from discovery to the clinic.

M. Tabrizi, A. Drake, L. Roskos, 2009, Drug discovery today.

Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics.

I. Wilson, H. Major, E. Lenz, 2004, Journal of pharmaceutical and biomedical analysis.

A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity.

I. Wilson, H. Major, E. Lenz, 2004, The Analyst.

Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis

J. S. McKay, J. Yates, P. Newham, 2014, Inflammation Research.

Analysis of time course 1H NMR metabolomics data by multivariate curve resolution

M. Viant, E. Lenz, T. Karakach, 2009, Magnetic resonance in chemistry : MRC.