D. Prosser

发表

Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1α,25-(OH)2D3-26,23-lactone

Glenville Jones, B. O’Leary, M. Kaufmann, 2007, Proceedings of the National Academy of Sciences.

Mutations in CYP24A1 and idiopathic infantile hypercalcemia.

M. Konrad, H. Fehrenbach, J. Hoenderop, 2011, The New England journal of medicine.

The Activating Enzymes of Vitamin D Metabolism (25- and 1α-Hydroxylases)

Glenville Jones, D. Prosser, 2011 .

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies.

Glenville Jones, S. Masuda, M. Kaufmann, 2007, Archives of biochemistry and biophysics.

Metabolism of a 20-methyl substituted series of vitamin D analogs by cultured human cells: apparent reduction of 23-hydroxylation of the side chain by the 20-methyl group.

A. Steinmeyer, H. Wiesinger, G. Jones, 2001, Biochemical pharmacology.

Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones.

A. Brancale, Glenville Jones, C. Simons, 2010, European journal of medicinal chemistry.

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D.

Glenville Jones, M. Kaufmann, D. Prosser, 2012, Archives of biochemistry and biophysics.

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation*

Glenville Jones, M. Kaufmann, D. Prosser, 2011, The Journal of Biological Chemistry.

Cytochrome P450-mediated metabolism of vitamin D

Glenville Jones, M. Kaufmann, D. Prosser, 2014, Journal of Lipid Research.

Enzymes involved in the activation and inactivation of vitamin D.

Glenville Jones, Glenville Jones, David E Prosser, 2004, Trends in biochemical sciences.

Isolation, sequencing and characterization of two cDNA clones coding for trypsin‐like enzymes from the midgut of Aedes aegypti

B. White, L. M. Tabak, W. Brook, 1993, Insect molecular biology.

Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation.

Z. Jia, Glenville Jones, D. Prosser, 2006, Biophysical journal.

Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides.

S. Yee, A. Brancale, Glenville Jones, 2010, Bioorganic & medicinal chemistry.

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation*

Glenville Jones, M. Kaufmann, D. Prosser, 2011, The Journal of Biological Chemistry.