Jeff Beckman

发表

Capillary electrophoresis and the biopharmaceutical industry: Therapeutic protein analysis and characterization

M. Szigeti, A. Guttman, Harleen Kaur, 2021 .

Purity Determination by Capillary Electrophoresis Sodium Hexadecyl Sulfate (CE-SHS): A Novel Application For Therapeutic Protein Characterization.

Naresh Chennamsetty, Z. Li, S. Krystek, 2018, Analytical chemistry.

Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase.

R. Kuchta, Nisha A. Cavanaugh, T. Spratt, 2009, Biochemistry.

Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase α

R. Halcomb, R. Kuchta, J. Engels, 2005, Nucleic acids research.

Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity.

Michal Hocek, R. Kuchta, J. Engels, 2006, Biochemistry.

Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite Guanidinohydantoin .

Jimin Wang, G. Blaha, W. Konigsberg, 2010, Biochemistry.

Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase.

W. Konigsberg, Chao Zhao, U. Subuddhi, 2011, Biochemistry.

Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus.

L. Beese, R. Kuchta, T. Spratt, 2009, Biochemistry.

Kinetic Analysis of Correct Nucleotide Insertion by a Y-family DNA Polymerase Reveals Conformational Changes Both Prior to and following Phosphodiester Bond Formation as Detected by Tryptophan Fluorescence*

F. Guengerich, P. Guengerich, Qixin Wang, 2008, Journal of Biological Chemistry.

Using a fluorescent cytosine analogue tC(o) to probe the effect of the Y567 to Ala substitution on the preinsertion steps of dNMP incorporation by RB69 DNA polymerase.

Jimin Wang, W. Konigsberg, S. Xia, 2012, Biochemistry.

RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity.

Jimin Wang, W. Konigsberg, Hong Zhang, 2009, Biochemistry.

Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .

Jimin Wang, G. Blaha, W. Konigsberg, 2010, Biochemistry.

Frameshift Deletion by Sulfolobus solfataricus P2 DNA Polymerase Dpo4 T239W Is Selective for Purines and Involves Normal Conformational Change Followed by Slow Phosphodiester Bond Formation*

F. Guengerich, Huidong Zhang, Jeff Beckman, 2009, The Journal of Biological Chemistry.

Enhancement of covalent aggregate quantification of protein therapeutics by non-reducing capillary gel electrophoresis using sodium hexadecyl sulfate (CE-SHS).

Z. Li, Ryan Knihtila, Jeff Beckman, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Minimization of artifact protein aggregation using tetradecyl sulfate and hexadecyl sulfate in capillary gel electrophoresis under reducing conditions

Z. Li, Jeff Beckman, Sergey Voronov, 2020, Electrophoresis.

Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase.

W. Konigsberg, Chao Zhao, U. Subuddhi, 2011, Biochemistry.