Vinay Sonawane

发表

Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells

B. Chaudhuri, S. Bharate, P. Joshi, 2017, J. Chem. Inf. Model..

Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells.

B. Chaudhuri, S. Bharate, Rajni K. Sharma, 2018, Bioorganic & medicinal chemistry.

Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells

K. Joshi, P. Shastry, R. Pujari, 2022, Cancers.

Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription.

K. Joshi, M. Rathos, S. Manohar, 2011, Leukemia research.

Quinazoline derivatives as selective CYP1B1 inhibitors.

B. Chaudhuri, S. Bharate, P. Joshi, 2017, European journal of medicinal chemistry.

Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.

B. Chaudhuri, B. N. Sinha, Venkatesan Jayaprakash, 2019, European journal of medicinal chemistry.

Biphenyl urea derivatives as selective CYP1B1 inhibitors.

B. Chaudhuri, S. Bharate, P. Joshi, 2016, Organic & biomolecular chemistry.

Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.

B. Chaudhuri, S. Bharate, P. Joshi, 2017, European journal of medicinal chemistry.

Prostate Apoptosis Response-4: a Therapeutic Target for Malignant Gliomas

K. Joshi, P. Shastry, Vinay Sonawane, 2021, Tumor Suppressor Par-4.

P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer

Sanjay Kumar, Dimple R. Bhatia, Somesh D. Sharma, 2014, Molecular Cancer.

Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1

B. Chaudhuri, S. Bharate, Rajni K. Sharma, 2018, ACS omega.

CYP enzymes, expressed within live human suspension cells, are superior to widely‐used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance

B. Chaudhuri, S. Bharate, B. N. Sinha, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalcone is a potent and selective CYP1A1 inhibitor and cancer chemopreventive agent.

B. Chaudhuri, S. Bharate, P. Joshi, 2017, Bioorganic & medicinal chemistry letters.

A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells

A. Jalota-Badhwar, Sanjay Kumar, K. Joshi, 2011, BMC Cancer.

Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy via screening of a natural product repository.

B. Chaudhuri, S. Bharate, P. Joshi, 2018, MedChemComm.

Ketorolac modulates Rac-1/HIF-1α/DDX3/β-catenin signalling via a tumor suppressor prostate apoptosis response-4 (Par-4) in renal cell carcinoma

K. Joshi, Vinay Sonawane, J. Ghosalkar, 2023, Scientific Reports.