Xiaoxi Zhuang

发表

Title: Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by in vitro Cellular Studies and in vivo PET Imaging Abbreviated Title: Trapping Hypothesis of Nicotine Addiction

C. Kao, Hannah J. Zhang, J. Mukherjee, 2021 .

New thiazole carboxamides as potent inhibitors of Akt kinases.

Honglin Li, Xianwen Cao, Xiaoyun Lu, 2012, Bioorganic & medicinal chemistry letters.

Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.

Yan Zhang, Yong Xu, H. Xu, 2022, Journal of medicinal chemistry.

Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.

Xiaoyun Lu, Deping Wang, R. Yu, 2015, Bioorganic & medicinal chemistry letters.

Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2022, European journal of medicinal chemistry.

Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist.

Yan Zhang, Donghai Wu, Benqiang Yao, 2022, Journal of medicinal chemistry.

N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors.

Yong Xu, J. Smaill, Donghai Wu, 2015, ACS medicinal chemistry letters.

Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.

Xiaoyun Lu, Zheng-chao Tu, Deping Wang, 2013, Journal of medicinal chemistry.

1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as orally bioavailable transcriptional function suppressors of estrogen-related receptor α.

Lei Duan, Shili Xu, Ke Ding, 2013, Journal of medicinal chemistry.

The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation

Qing Dai, Sigrid Nachtergaele, Junmin Peng, 2022, The Journal of biological chemistry.

1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose.

Yong Xu, J. Smaill, Donghai Wu, 2015, Bioorganic & medicinal chemistry.

Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer.

Yan Zhang, Yong Xu, X. Kong, 2021, Journal of medicinal chemistry.

Drosophila carrying epilepsy-associated variants in the vitamin B6 metabolism gene PNPO display allele- and diet-dependent phenotypes

Atulya S R Iyengar, Wanhao Chi, C. Wu, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Rational design, synthesis and biological evaluation of benzo[d]isoxazole derivatives as potent BET bivalent inhibitors for potential treatment of prostate cancer.

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2023, Bioorganic chemistry.

Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist.

Yan Zhang, Yong Xu, Donghai Wu, 2021, Journal of Medicinal Chemistry.

New benzimidazole-2-urea derivates as tubulin inhibitors.

Yong Xu, Dexin Kong, Xiaohong Yang, 2014, Bioorganic & medicinal chemistry letters.

Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by In Vitro Cellular Studies and In Vivo PET Imaging

C. Kao, Hannah J. Zhang, J. Mukherjee, 2021, The Journal of Neuroscience.

Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia

Yan Zhang, Qiu-ping Xiang, Tian Wu, 2023, Bioorganic Chemistry.