P. Mayeux

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Meprin A and meprin α generate biologically functional IL-1 β from pro-IL-1 β

Sudhir V. Shah, G. Kaushal, C. Herzog, 2013 .

Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1beta.

Sudhir V. Shah, G. Kaushal, C. Herzog, 2009, Biochemical and biophysical research communications.

Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury.

N. Gokden, H. Spencer, Zhen Wang, 2012, The American journal of pathology.

Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney.

C. Zhang, L. M. Walker, P. Mayeux, 2000, Biochemical pharmacology.

Nitric oxide generation by renal proximal tubules: role of nitric oxide in the cytotoxicity of lipid A.

J. Proksch, P. Mayeux, L. Traylor, 1996, The Journal of pharmacology and experimental therapeutics.

Thromboxane, prostaglandin and leukotriene receptors.

P. Halushka, T. Morinelli, D. Mais, 1989, Annual review of pharmacology and toxicology.

Glomerular thromboxane A2/prostaglandin H2 receptors: characterization and effect of adriamycin-induced nephrotic syndrome.

S. Shah, P. Mayeux, 1993, Biochimica et biophysica acta.

Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor.

P. Halushka, D. Mais, P. Mayeux, 1991, European journal of pharmacology.

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury.

N. Gokden, Zhen Wang, Kathryn A. Seely, 2012, Kidney international.

Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis

G. Kaushal, C. Herzog, Zhen Wang, 2009, Shock.

Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.

P. Halushka, D. Knapp, T. Morinelli, 1989, The Journal of pharmacology and experimental therapeutics.

Peroxynitrite and the regulation of Na(+),K(+)-ATPase activity by angiotensin II in the rat proximal tubule.

S. Imam, S. Ali, P. Mayeux, 2002, Nitric oxide : biology and chemistry.

Acting at CB2 Receptors

J. L. Shoemaker, M. B. Ruckle, P. Prather, 2005 .

Lack of a role for inducible nitric oxide synthase in an experimental model of nephrotic syndrome.

S. Shah, L. M. Walker, P. Mayeux, 2000, Biochemical pharmacology.

Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury.

L. MacMillan-Crow, N. Parajuli, P. Mayeux, 2014, American journal of physiology. Renal physiology.

Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.

E. Hazard, P. Halushka, T. Morinelli, 1991, The Journal of biological chemistry.

Superoxide generation by renal proximal tubule nitric oxide synthase.

P. Mayeux, L. Traylor, 1997, Nitric oxide : biology and chemistry.

Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2.

S. Shah, P. Walker, N. Ueda, 1991, Kidney international.

Molecular Cloning and Functional Characterization of a Vasotocin Receptor Subtype That Is Expressed in the Shell Gland and Brain of the Domestic Chicken1

M. Brownstein, D. A. Baeyens, V. Macleod, 2000, Biology of reproduction.

Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis.

L. MacMillan-Crow, P. Mayeux, 2018, Internal medicine review.

Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis

L. MacMillan-Crow, C. Sims, P. Mayeux, 2014, Clinical pharmacology and therapeutics.

Disruption of renal peritubular blood flow in lipopolysaccharide-induced renal failure: role of nitric oxide and caspases.

J. Megyesi, G. Kaushal, R. Brock, 2005, American journal of physiology. Renal physiology.

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.

P. R. Mayeux, J. Hinson, T. Bucci, 2002, Nitric oxide : biology and chemistry.

Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl)lysine.

P. Walker, S. Ali, L. M. Walker, 2000, The Journal of pharmacology and experimental therapeutics.

Mechanism of Bradykinin-Induced Ca2+ Mobilization in Murine Proximal Tubule Epithelial Cells

P. Prather, P. Mayeux, Manish M Tiwari, 2005, Journal of Pharmacology and Experimental Therapeutics.

Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor

L. Cornett, M. Mikhailova, P. Mayeux, 2008, Journal of biomedical optics.

Effects of the Inducible Nitric-Oxide Synthase Inhibitor l-N6-(1-Iminoethyl)-lysine on Microcirculation and Reactive Nitrogen Species Generation in the Kidney following Lipopolysaccharide Administration in Mice

Liping Wu, P. Mayeux, 2007, Journal of Pharmacology and Experimental Therapeutics.

Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice.

N. Gokden, R. Brock, Liping Wu, 2007, American journal of physiology. Renal physiology.

The affinities of prostaglandin H2 and thromboxane A2 for their receptor are similar in washed human platelets.

J. Gillard, P. Halushka, T. Morinelli, 1988, Biochemical and biophysical research communications.

Acetaminophen-induced hepatotoxicity.

Laura P James, Philip R Mayeux, Jack A Hinson, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors augments CRH-stimulated 3',5'-cyclic adenosine monophosphate production.

W. Kuenzel, Ye Chen, A. Periasamy, 2007, Molecular endocrinology.

Bradykinin-induced chloride conductance in murine proximal tubule epithelial cells

J. Stimers, P. Mayeux, Manish M Tiwari, 2007, Molecular and Cellular Biochemistry.

Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor

D. A. Baeyens, Stacie M Jones, J. Kirby, 2003, Regulatory Peptides.

Pathobiology of lipopolysaccharide.

P. Mayeux, 1997, Journal of toxicology and environmental health.

Evidence for a bidirectional prostaglandin endoperoxide shunt between platelets and the bovine coronary artery.

P. Kadowitz, D. B. McNamara, P. Mayeux, 1989, Biochimica et biophysica acta.

Prostacyclin, Thromboxane A2, and Prostaglandin E2 Formation in Atherosclerotic Human Carotid Artery

M. Kerstein, P. Kadowitz, A. Hyman, 1988, Arteriosclerosis.

Could Biomarkers Direct Therapy for the Septic Patient?

T. Nguyen, C. Sims, Trung C. Nguyen, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

K. Muldrew, H. Hendrickson, Laura P James, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability

V. Lupashin, P. R. Mayeux, Yicong Li, 2016, Scientific Reports.

The Endothelium in Sepsis

T. Nguyen, J. Kellum, G. Ospina-Tascón, 2016, Shock.

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

N. Pumford, J. Hinson, S. L. Michael, 1999, Hepatology.

Nitric oxide generation mediates lipid A-induced oxidant injury in renal proximal tubules.

P. Mayeux, L. Traylor, Linda A. Traylor, 1997, Archives of biochemistry and biophysics.

The pharmacological effects of allicin, a constituent of garlic oil

H. Lippton, P. R. Mayeux, K. Agrawal, 1988, Agents and Actions.

Oxidative stress and reactive nitrogen species generation during renal ischemia.

K. Muldrew, S. Imam, Syed F. Ali, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of lipid A on calcium homeostasis in renal proximal tubules.

J. Proksch, P. Mayeux, L. Traylor, 1996, The Journal of pharmacology and experimental therapeutics.

Intracellular calcium mediates the cytotoxicity of lipid A in LLC-PK1 cells.

S. Shah, P. Mayeux, 1993, The Journal of pharmacology and experimental therapeutics.

Microvascular Dysfunction in the Critically Ill.

C. Ince, D. De Backer, P. Mayeux, 2020, Critical care clinics.

Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.

L. MacMillan-Crow, P. Mayeux, 2012, Pharmacology & therapeutics.

Oxidant stress in rat liver after lipopolysaccharide administration: effect of inducible nitric-oxide synthase inhibition.

J. Hinson, C. Zhang, L. M. Walker, 2000, The Journal of pharmacology and experimental therapeutics.

Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse

C. Sims, P. R. Mayeux, N. Gokden, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Retraction Note: Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability

V. Lupashin, P. R. Mayeux, Yicong Li, 2016, Scientific Reports.

Inducible nitric oxide synthase and apoptosis in murine proximal tubule epithelial cells

P. Mayeux, Manish M Tiwari, Kurt J Messer, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

NO/cGMP signaling modulates regulation of Na+-K+-ATPase activity by angiotensin II in rat proximal tubules.

C. Zhang, P. Mayeux, 2001, American journal of physiology. Renal physiology.

Evidence for the role of reactive nitrogen species in polymicrobial sepsis-induced renal peritubular capillary dysfunction and tubular injury.

Philip R Mayeux, Liping Wu, Neriman Gokden, 2007, Journal of the American Society of Nephrology : JASN.

Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity.

N. Pumford, A. Warbritton, J. Hinson, 2001, Nitric oxide : biology and chemistry.

Agonist-Directed Trafficking of Response by Endocannabinoids Acting at CB2 Receptors

Philip R Mayeux, J. L. Shoemaker, M. B. Ruckle, 2005, Journal of Pharmacology and Experimental Therapeutics.

The Endocannabinoid Noladin Ether Acts as a Full Agonist at Human CB2 Cannabinoid Receptors

P. R. Mayeux, J. L. Shoemaker, Biny K. Joseph, 2005, Journal of Pharmacology and Experimental Therapeutics.

Angiotensin II signaling activities the NO-cGMP pathway in rat proximal tubules.

C. Zhang, P. Mayeux, 1998, Life sciences.

Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome

T. Nguyen, S. Mu, Sharda P. Singh, 2017, Front. Pharmacol..

Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite.

D. Doerge, J. Hinson, P. Mayeux, 2010, Biochemical pharmacology.

Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice.

N. Pumford, P. R. Mayeux, J. Hinson, 1998, Chemical research in toxicology.

Differential effects of ibuprofen, indomethacin, and meclofenamate on prostaglandin endoperoxide H2 metabolism

P. Kadowitz, D. B. McNamara, P. Mayeux, 1989, Molecular and Cellular Biochemistry.

Delayed Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis*

R. Schnellmann, Joshua A. Smith, P. Mayeux, 2016, Critical care medicine.

Effect of lipopolysaccharide on nitric oxide synthase activity in rat proximal tubules.

J. Gibson, P. Mayeux, V. C. Beanum, 1995, Biochemical pharmacology.

In vitro model of sepsis-induced renal epithelial reactive nitrogen species generation.

P. Mayeux, Elina Pathak, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Role of Mitochondrial Oxidants in an In Vitro Model of Sepsis-Induced Renal Injury

L. MacMillan-Crow, P. Mayeux, Elina Pathak, 2012, Journal of Pharmacology and Experimental Therapeutics.

Human erythroleukemia cells express functional thromboxane A2/prostaglandin H2 receptors.

P. Halushka, C. Carr, D. Mais, 1989, The Journal of pharmacology and experimental therapeutics.

Hemodynamic changes in the kidney in a pediatric rat model of sepsis-induced acute kidney injury.

N. Gokden, Zhen Wang, Kathryn A. Seely, 2011, American journal of physiology. Renal physiology.

Rolipram Improves Renal Perfusion and Function during Sepsis in the Mouse

N. Gokden, Zhen Wang, P. Mayeux, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Nitrosative stress and lipid homeostasis as a mechanism for zileuton hepatotoxicity and resistance in genetically sensitive mice.

D. Gatti, W. Mattes, L. James, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Prostaglandins and Defects in Vascular Function

M. Kerstein, P. Kadowitz, A. Hyman, 1987 .

Prostaglandin Synthesis in Atherosclerotic Human Carotid Artery

M. Kerstein, P. Kadowitz, A. Hyman, 1987 .

Acetaminophen-induced hepatotoxicity.

L. James, J. Hinson, P. Mayeux, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Liping Wu, P. Mayeux, 2007, Journal of Pharmacology and Experimental Therapeutics.

Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor

M. Mikhailova, P. Mayeux, S. Jacobi, 2008, Journal of biomedical optics.

Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl)lysine.

P. Mayeux, Lisa M. Walker, Patrick D. Walker, 2000, The Journal of pharmacology and experimental therapeutics.

Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse

C. Sims, N. Gokden, Zhen Wang, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Hemodynamic changes in the kidney in a pediatric rat model of sepsis-induced acute kidney injury.

N. Gokden, Zhen Wang, Kathryn A. Seely, 2011, American journal of physiology. Renal physiology.

Genome-wide linkage analyses of non-Hispanic White families identifies novel loci for familial late-onset Alzheimer ' s disease

Vance, M. Cuccaro, J. Haines, 2016 .

Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis

L. MacMillan-Crow, C. Sims, P. Mayeux, 2014, Clinical pharmacology and therapeutics.

Renal Mitochondrial Lipid Peroxidation during Sepsis

L. MacMillan-Crow, N. Parajuli, P. Mayeux, 2016, Journal of kidney.