A. Chenna

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p95HER2–T cell bispecific antibody for breast cancer treatment

C. Klein, J. Baselga, J. Tabernero, 2018, Science Translational Medicine.

Synthesis of the Fully Protected Phosphoramidite of the Benzene-DNA Adduct, N 2-(4-Hydroxyphenyl)-2′-Deoxyguanosine and Incorporation of the Later into DNA Oligomers

F. Johnson, R. Bonala, B. Hang, 2008, Nucleosides, Nucleotides & Nucleic Acids.

Markers of Fungal Translocation Are Elevated During Post-Acute Sequelae of SARS-CoV-2 Infection and Induce NF-κB Triggered Inflammation

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2022, bioRxiv.

Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

M. Peluso, Jeffrey N. Martin, D. Glidden, 2021, The Journal of infectious diseases.

Synthesis of 8-(hydroxymethyl)-3,N(4)-etheno-2'-deoxycytidine, a potential carcinogenic glycidaldehyde adduct, and its site-specific incorporation into DNA oligonucleotides.

B. Singer, A. Perry, A. Chenna, 2000, Chemical research in toxicology.

High p95HER2/HER2 Ratio Associated With Poor Outcome in Trastuzumab-Treated HER2-Positive Metastatic Breast Cancer NCCTG N0337 and NCCTG 98-32-52 (Alliance)

E. Perez, C. Petropoulos, A. Dueck, 2018, Clinical Cancer Research.

Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA.

B. Hang, A. Guliaev, A. Chenna, 2010, Toxicology letters.

Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2022, JCI insight.

Thirdhand smoke causes DNA damage in human cells.

P. Jacob, H. Destaillats, L. Gundel, 2013, Mutagenesis.

p95HER2 Methionine 611 Carboxy-Terminal Fragment Is Predictive of Trastuzumab Adjuvant Treatment Benefit in the FinHer Trial

Aki Vehtari, C. Petropoulos, H. Joensuu, 2018, Clinical Cancer Research.

Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2022, medRxiv : the preprint server for health sciences.

Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection

M. Peluso, Jeffrey N. Martin, D. Glidden, 2022, Neurology: Neuroimmunology & Neuroinflammation.

Post-acute sequelae and adaptive immune responses in people living with HIV recovering from SARS-COV-2 infection.

M. Peluso, A. Sette, Jeffrey N. Martin, 2022, AIDS.

Quantitative Measurements of Tumoral p95HER2 Protein Expression in Metastatic Breast Cancer Patients Treated with Trastuzumab: Independent Validation of the p95HER2 Clinical Cutoff

J. Jassem, W. Biernat, Weidong Huang, 2014, Clinical Cancer Research.

Evaluation of SARS-CoV-2 nucleocapsid antigen in the blood as a diagnostic test for infection and infectious viral shedding

M. Peluso, Jeffrey N. Martin, D. Glidden, 2022, Open forum infectious diseases.

Higher cerebrospinal fluid biomarkers of neuronal injury in HIV-associated neurocognitive impairment

C. Petropoulos, R. Ellis, S. Letendre, 2022, Journal of NeuroVirology.

Quantitative HER2 and p95HER2 levels in primary breast cancers and matched brain metastases.

J. Jassem, W. Biernat, T. Trojanowski, 2015, Neuro-oncology.

Functionalised benzocyclo-octenones: synthesis and chemistry

G. Proctor, J. A. Donnelly, A. Chenna, 1990 .

Functionalised Benzocyclooctenones: Synthesis and Chemistry.

G. Proctor, J. A. Donnelly, A. Chenna, 1990 .

Replication of O4-methylthymine-containing oligonucleotides: effect of 3' and 5' flanking bases on formation and extension of O4-methylthymine . guanine basepairs.

M. Slupska, B. Singer, A. Chenna, 1996, Mutation research.

Prolonged Response to Trastuzumab in a Patient With HER2-Nonamplified Breast Cancer With Elevated HER2 Dimerization Harboring an ERBB2 S310F Mutation.

E. Perez, Siraj M. Ali, S. Balasubramanian, 2015, Journal of the National Comprehensive Cancer Network : JNCCN.

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

Lin Wang, J. Grandis, Hua Li, 2015, Clinical Cancer Research.

A Novel Proximity Assay for the Detection of Proteins and Protein Complexes: Quantitation of HER1 and HER2 Total Protein Expression and Homodimerization in Formalin-fixed, Paraffin-Embedded Cell Lines and Breast Cancer Tissue

Yining Shi, John Winslow, Weidong Huang, 2009, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Impact of pre-existing chronic viral infection and reactivation on the development of long COVID.

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2022, The Journal of clinical investigation.

The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.

W. Bodell, B. Rydberg, E. Kim, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients

J. Grandis, Seungwon Kim, J. Bauman, 2019, Clinical Cancer Research.

Multiplex mRNA assay using electrophoretic tags for high-throughput gene expression analysis.

Mengxiang Tang, Sharat Singh, Ahmed Chenna, 2004, Nucleic acids research.

An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site.

H. Fraenkel-conrat, B. Hang, B. Singer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Profiling the HER3/PI3K Pathway in Breast Tumors Using Proximity-Directed Assays Identifies Correlations between Protein Complexes and Phosphoproteins

Stephen Williams, Ali Mukherjee, Youssouf Badal, 2011, PloS one.

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer

C. Petropoulos, C. Singer, R. Horvat, 2013, Breast Cancer Research and Treatment.

High HER2 Expression Correlates with Response to the Combination of Lapatinib and Trastuzumab

M. Piccart, L. Pusztai, J. Baselga, 2014, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine Quantitative Measurements of Tumoral p 95 HER 2 Protein Expression in Metastatic Breast Cancer Patients Treated with Trastuzumab : Independent Validation of the p 95 HER 2 Clinical Cutoff

J. Jassem, W. Biernat, Weidong Huang, 2014 .

Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV.

B. Hang, B. Singer, A. Chenna, 1998, Carcinogenesis.

A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex.

J. Sagi, B. Hang, B. Singer, 1998, Chemical research in toxicology.

All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.

H. Fraenkel-conrat, M. Dosanjh, E. Kim, 1994, Proceedings of the National Academy of Sciences of the United States of America.

HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant.

Rosemary H. Tambouret, John Winslow, B. Rueda, 2015, Gynecologic oncology.

1,N6-ethenoadenine and 3,N4-ethenocytosine are excised by separate human DNA glycosylases.

B. Hang, B. Singer, A. Chenna, 1996, Carcinogenesis.

Inflammation during early post-acute COVID-19 is associated with reduced exercise capacity and Long COVID symptoms after 1 year.

C. Long, M. Peluso, Jeffrey N. Martin, 2022, medRxiv : the preprint server for health sciences.

Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection

M. Peluso, A. Sette, Jeffrey N. Martin, 2022 .

Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2022, JCI insight.

Adverse Health Effects of Thirdhand Smoke: From Cell to Animal Models

A. Snijders, Yankai Xia, J. Mao, 2017, International journal of molecular sciences.

Synthesis of a benzene metabolite adduct, 3"-hydroxy-1,N2-benzetheno-2'-deoxyguanosine, and its site-specific incorporation into DNA oligonucleotides.

B. Singer, A. Chenna, 1997, Chemical research in toxicology.

Large Scale Synthesis of p-Benzoquinone-2'-Deoxycytidine and p-Benzoquinone-2'-Deoxyadenosine Adducts and Their Site-Specific Incorporation into DNA Oligodeoxyribonucleotides

B. Singer, A. Chenna, 1995 .

Large scale synthesis of p-benzoquinone-2'-deoxycytidine and p-benzoquinone-2'-deoxyadenosine adducts and their site-specific incorporation into DNA oligonucleotides.

B. Singer, A. Chenna, 1995, Chemical research in toxicology.

Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea.

B. Hang, A. Guliaev, B. Singer, 2003, Mutation research.

Chronic viral coinfections differentially affect the likelihood of developing long COVID

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2023, The Journal of Clinical Investigation.

Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection

M. Peluso, Jeffrey N. Martin, C. Petropoulos, 2021, medRxiv.

Characterization of thymidine adducts formed by acrolein and 2-bromoacrolein.

C. Iden, R. Rieger, A. Chenna, 1992, Carcinogenesis.

Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection

Winslow, M. Peluso, Jeffrey N. Martin, 2023, medRxiv.

Reduced Exercise Capacity, Chronotropic Incompetence, Inflammation and Symptoms in Post-Acute COVID-19

C. Long, M. Peluso, D. Glidden, 2022, medRxiv.

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

Lin Wang, J. Grandis, Hua Li, 2015, Clinical Cancer Research.

Characterization of 2'-deoxycytidine and 2'-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein.

C. Iden, A. Chenna, 1993, Chemical research in toxicology.

Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection

M. Peluso, A. Sette, D. Weiskopf, 2022, AIDS.

Quantitative HER2 and p95HER2 levels in primary breast cancers and matched brain metastases.

J. Jassem, W. Biernat, T. Trojanowski, 2015, Neuro-oncology.

Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID.

C. Long, M. Peluso, D. Glidden, 2023, The Journal of infectious diseases.

Abstract 3029: Profiling HER3/ErbB3 activation in formalin-fixed, paraffin-embedded (FFPE) breast tumor samples that express high and low HER2/ErbB2 levels using proximity-based immunoassays.

C. Petropoulos, K. Thress, C. Womack, 2013 .