J. Herault

发表

Specific Inhibition of the VEGFR-3 Tyrosine Kinase by SAR131675 Reduces Peripheral and Tumor Associated Immunosuppressive Myeloid Cells

Nicolas Espagnolle, F. Bono, P. Savi, 2014, Cancers.

Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond

J. Herbert, J. Mallet, M. Petitou, 1997 .

Tumor Vasculature Is Regulated by FGF/FGFR Signaling‐Mediated Angiogenesis and Bone Marrow‐Derived Cell Recruitment: This Mechanism Is Inhibited by SSR128129E, the First Allosteric Antagonist of FGFRs

J. Herbert, F. Géronimi, F. Bono, 2015, Journal of cellular physiology.

Synthesis of Conformationally Locked Carbohydrates: A Skew-Boat Conformation of L-Iduronic Acid Governs the Antithrombotic Activity of Heparin.

J. Herbert, S. Das, J. Mallet, 2001, Angewandte Chemie.

by direct binding to CD160 receptor expressed by endothelial cells Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and

Judith E. Cartwright, F. Malecaze, P. Fons, 2011 .

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cells survival and migration Running title: Neuropilin-2 enhances VEGFR-2 cellular responses

G. Neufeld, J. Herbert, F. Bono, 2006 .

Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells.

Judith E. Cartwright, F. Malecaze, S. Fournel, 2006, Blood.

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.

P. Carmeliet, J. Herbert, B. Ruggeri, 2004, Biochemical and biophysical research communications.

SAR131675, a Potent and Selective VEGFR-3–TK Inhibitor with Antilymphangiogenic, Antitumoral, and Antimetastatic Activities

F. Bono, P. Savi, I. Blanc, 2012, Molecular Cancer Therapeutics.

FcγRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

J. Herbert, B. Payrastre, M. Plantavid, 2000 .

Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin.

J. Kelton, J. Herbert, Y. Gruel, 2005, Blood.

Synthesis of thrombin-inhibiting heparin mimetics without side effects

J. Herbert, M. Petitou, J. Lormeau, 1999, Nature.

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems Comparison with heparin and low-molecular-weight heparin

S. Olson, J. Herbert, I. Björk, 2004, Thrombosis and Haemostasis.

Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin

P. Carmeliet, L. Moons, D. Collen, 2003, Circulation research.

Heparin-Binding Domain of Antithrombin Life-Threatening Thrombosis in Mice With Targeted Arg 48-to-Cys Mutation of the Print

P. Carmeliet, L. Moons, D. Collen, 2003 .

Soluble HLA-G and control of angiogenesis.

Judith E. Cartwright, P. Le Bouteiller, F. Bono, 2007, Journal of reproductive immunology.

Synthesis of new conformationally constrained pentasaccharides as molecular probes to investigate the biological activity of heparin.

J. Herbert, J. Mallet, M. Petitou, 2003, Biochimie.

Effects of SanOrg123781A, a synthetic heparin mimetic, in a mouse model of electrically induced carotid artery injury: synergism with the antiplatelet agent clopidogrel.

J. Herbert, R. Masson, J. Lorrain, 2003 .

Fc g RIIA requires a Gi-dependent pathway for an efﬁcient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

J. Herbert, B. Payrastre, M. Plantavid, 2000 .

SSR182289A, a Novel, Orally Active Thrombin Inhibitor: In Vitro Profile and ex Vivo Anticoagulant Activity

J. Herbert, G. Lassalle, F. Guilbert, 2002, Journal of Pharmacology and Experimental Therapeutics.

Synthesis of Conformationally Locked L-Iduronic Acid Derivatives. Direct Evidence for a Critical Role of the Skew-Boat 2S0 Conformer in the Activation of Antithrombin by Heparin.

J. Herbert, S. Das, J. Mallet, 2002 .

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

SSR182289A, a selective and potent orally active thrombin inhibitor.

J. Herbert, Z. Bocskei, J. Lorrain, 2004, Bioorganic & medicinal chemistry.

Effects of SanOrg123781A, a Synthetic Hexadecasaccharide, in a Mouse Model of Electrically Induced Carotid Artery Injury: Synergism with the Antiplatelet Agent Clopidogrel

N. Roome, J. Herbert, R. Masson, 2004, Journal of Pharmacology and Experimental Therapeutics.

JPET # 59873 1 Effects of SanOrg 123781 A , a synthetic heparin mimetic , in a mouse model of electrically induced carotid artery injury : synergism with the antiplatelet agent clopidogrel

N. Roome, J. Herbert, R. Masson, 2003 .

N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.

J. Herbert, N. Delesque, L. Millet, 2014, Journal of medicinal chemistry.

216471 ) , a Novel Intravenous and Oral , Reversible , and Directly Acting P 2 Y 12 Antagonist

J. Herbert, N. Delesque, L. Millet, 2014 .

Antidiuretic factor from the nervous corpora cardiaca of the migratory locust: improvement of an existing in vitro bioassay.

B. Fournier, J. Herault, J. Proux, 1987, General and comparative endocrinology.

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

Jie Zhang, Harald Schwalbe, Francesco Luigi Gervasio, 2013, Cancer cell.

Separation and characteristics of antidiuretic factors from the corpora cardiaca of the migratory locust

J. Girardie, J. Herault, J. Proux, 1985 .

Diuretic activity of a newly identified neuropeptide—The arginine-vasopressin-like insect diuretic hormone: Use of an improved bioassay

B. Fournier, J. Herault, J. Proux, 1988 .

Further Characterization of the Antidiuretic Factor From the Glandular Part of the Corpora Cardiaca of the Migratory Locust

J. Girardie, J. Herault, J. Proux, 1988 .

Cyclic AMP: The second messenger of an antidiuretic hormone from the glandular lobes of the migratory locust corpora cardiaca

J. Herault, J. Proux, 1987 .

Cyclic AMP: A second messenger of the newly characterized AVP-like insect diuretic hormone, the migratory locust diuretic hormone

J. Herault, J. Proux, 1988, Neuropeptides.

Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.

T. Blundell, P. Carmeliet, K. Saxena, 2013, Cancer cell.

Comparative Inhibition of Extrinsic and Intrinsic Thrombin Generation by Standard Heparin, a Low Molecular Weight Heparin and the Synthetic ATIII-Binding Pentasaccharide

J. Hérault, J. Lormeau, J. Herault, 1993, Thrombosis and Haemostasis.

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

J. Herbert, L. Millet, J. Hérault, 2008, Journal of thrombosis and haemostasis : JTH.

Human umbilical vein endothelial cells express high affinity receptors for factor Xa

J. Herbert, F. Bono, J. Lormeau, 1997, Journal of cellular physiology.

Factor Xa Activates Endothelial Cells by a Receptor Cascade Between EPR-1 and PAR-2

J. Herbert, F. Bono, J. Guillemot, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

J. Herbert, J. Hérault, J. Mallet, 1997 .

Automated Image Analysis of In Vitro Angiogenesis Assay

Hugues Talbot, Marie-Laure Boizeau, Pierre Fons, 2013, Journal of laboratory automation.

VEGF‐R2 and neuropilin‐1 are involved in VEGF‐A‐induced differentiation of human bone marrow progenitor cells

J. Herbert, N. Delesque, F. Bono, 2004, Journal of cellular physiology.

Effect of Clopidogrel on Thrombin Generation in Platelet-Rich Plasma in the Rat

J. Herbert, J. Hérault, A. Bernat, 1999, Thrombosis and Haemostasis.

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.

G. Neufeld, J. Herbert, F. Bono, 2006, Blood.

Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis

P. Ferrara, G. Favre, J. Herbert, 2014, The Journal of Biological Chemistry.

FcgammaRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation.

J. Herbert, B. Payrastre, M. Plantavid, 2000, Blood.

Activity of a synthetic hexadecasaccharide (SanOrg123781A) in a pig model of arterial thrombosis 1

M. Bonneau, J. Herbert, J. Hérault, 2004, Journal of thrombosis and haemostasis : JTH.

Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540).

J. Herbert, J. Hérault, M. Petitou, 1997, Journal of medicinal chemistry.

Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide.

J. Herbert, J. Hérault, P. Hoffmann, 1998, Blood.

Investigation of the selectivity of thrombin-binding aptamers for thrombin titration in murine plasma.

J. Herbert, A. Gué, A. Bancaud, 2016, Biosensors & bioelectronics.

Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin.

J. Herbert, J. Hérault, J. Lormeau, 1996, Thrombosis and haemostasis.

Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.

J. Herbert, J. Hérault, F. Bono, 1998, The Journal of clinical investigation.

Investigation of the selectivity of thrombin-binding aptamers for thrombin titration in murine plasma.

J. Herbert, A. Gué, A. Bancaud, 2016, Biosensors & bioelectronics.

Synthetic oligosaccharides having various functional domains: potent and potentially safe heparin mimetics.

J. Herbert, J. Hérault, M. Petitou, 1999, Bioorganic & medicinal chemistry letters.

Introducing a C-interglycosidic bond in a biologically active pentasaccharide hardly affects its biological properties.

J. Herbert, J. Hérault, J. Mallet, 1998, Bioorganic & medicinal chemistry.

Biochemical and pharmacological properties of SANORG 32701. Comparison with the "synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin.

J. Herbert, J. Hérault, M. Petitou, 1996, Circulation research.

The Effect of the Synthetic Pentasaccharide SR 90107/ORG 31540 on Thrombin Generation Ex Vivo Is Uniquely due to ATIII-Mediated Neutralization of Factor Xa

J. Hérault, J. Lormeau, J C Lormeau, 1995, Thrombosis and Haemostasis.

Determination of the anti-factor Xa activity of the synthetic pentasaccharide SR 90107A/ORG 31540 and of two structural analogues.

J. Herbert, J. Hérault, J. Lormeau, 1997, Thrombosis research.

Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes

I. Castan-Laurell, C. Dray, O. Kunduzova, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis

P. Ferrara, G. Favre, J. Herbert, 2014, The Journal of Biological Chemistry.

Effect of SanOrg123781A, a synthetic hexadecasaccharide, on clot‐bound thrombin and factor Xa in vitro and in vivo

L. Millet, J. Herault, Jean-Marc Herbert, 2003, Journal of thrombosis and haemostasis : JTH.