Keiko Kakegawa

Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obesity

H. Oki, Masanori Watanabe, Sachiko Itono, 2022, Journal of medicinal chemistry.

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition.

Masaharu Nakayama, S. Okuda, Masashi Takahashi, 2016, Bioorganic & medicinal chemistry.

Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors.

Biching Sang, C. Mol, D. Dougan, 2011, Bioorganic & medicinal chemistry letters.

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test.

Masaharu Nakayama, S. Okuda, Masashi Takahashi, 2016, Bioorganic & medicinal chemistry.

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

H. Oki, T. Ohashi, Yuta Tanaka, 2022, Journal of medicinal chemistry.

Melanin-Concentrating Hormone Receptor 1 Antagonists Lacking an Aliphatic Amine: Synthesis and Structure-Activity Relationships of Novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one Derivatives.

Masaharu Nakayama, Masashi Takahashi, H. Hirabayashi, 2016, Journal of medicinal chemistry.

Melanin-Concentrating Hormone Receptor 1 Antagonists Lacking an Aliphatic Amine: Synthesis and Structure-Activity Relationships of Novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one Derivatives.

Masaharu Nakayama, Masashi Takahashi, H. Hirabayashi, 2016, Journal of Medicinal Chemistry.

Discovery of a novel series of medium-sized cyclic enteropeptidase inhibitors.

Sachiko Itono, K. Fukuda, Naohiro Taya, 2023, Bioorganic & medicinal chemistry.