Kristin C Hicks

发表

Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

J. Schlom, Karin M. Knudson, Y. Ozawa, 2021, Oncoimmunology.

Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy

J. Schlom, W. Figg, S. Rabizadeh, 2019, Clinical Cancer Research.

Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

J. Schlom, Paul L. Chariou, S. Gameiro, 2022, Journal for ImmunoTherapy of Cancer.

Ferroptosis of tumour neutrophils causes immune suppression in cancer

J. Tobias, G. Kar, A. Greenberg, 2022, Nature.

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

J. Schlom, Karin M. Knudson, Y. Ozawa, 2020, Journal for ImmunoTherapy of Cancer.

Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced Stage Breast Cancer

S. Steinberg, J. Schlom, S. Lipkowitz, 2021, Frontiers in Oncology.

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

M. Cam, J. Schlom, Paul L. Chariou, 2021, Nature Communications.

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

J. Schlom, Karin M. Knudson, C. Allen, 2018, Oncoimmunology.

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

J. Schlom, Karin M. Knudson, Xiaoling Luo, 2018, Oncoimmunology.

Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

P. Neumann, Xianlong Gao, T. Patel, 2017, PloS one.

Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy

J. Schlom, Karin M. Knudson, S. Gameiro, 2019, Journal of Immunotherapy for Cancer.

Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins*

S. Gygi, B. Zhai, Xianlong Gao, 2011, The Journal of Biological Chemistry.

Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes*

T. Patel, Kristin C Hicks, 2016, The Journal of Biological Chemistry.

Myeloid Cell–Derived Oxidized Lipids and Regulation of the Tumor Microenvironment

Y. Tyurina, V. Kagan, D. Gabrilovich, 2021, Cancer Research.

Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer.

E. Wherry, T. Slidel, G. Kar, 2021, The Journal of clinical investigation.

Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

L. Rohlin, S. Benz, J. Z. Sanborn, 2019, Cancer Immunology Research.

D-104 Harnessing the potential of HDAC inhibitors for immunotherapy combinations

J. Schlom, J. Hodge, S. Gameiro, 2019, JAIDS Journal of Acquired Immune Deficiency Syndromes.