Zhendong Song

发表

Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies

Xiao-Feng Xiong, Yang Sun, Zhendong Song, 2020, Acta pharmaceutica Sinica. B.

Cleavable and tunable cysteine-specific arylation modification with aryl thioethers†

A. Chan, Huilin Li, Xiao-Feng Xiong, 2021, Chemical science.

Cleavable Cys labeling directed Lys site-selective stapling and single-site modification

A. Chan, Xiao-Feng Xiong, Zhendong Song, 2022, Science China Chemistry.

Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects.

Xiao-Feng Xiong, Yi-You Huang, Yifan Yang, 2022, Biochemical pharmacology.

Cleavable Cys labeling directed Lys site-selective stapling and single-site modification

A. Chan, Xiao-Feng Xiong, Zhendong Song, 2022, Science China Chemistry.

Identification of novel Pyrrolo[2,3-d]Pyrimidine-based KRAS G12C inhibitors with anticancer effects.

A. Chan, Xiao-Feng Xiong, Xiaolei Zhang, 2022, European journal of medicinal chemistry.

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

Xiao-Feng Xiong, Xiaolei Zhang, Shumin Ouyang, 2022, Acta pharmaceutica Sinica. B.

Adenine: an important drug scaffold for the design of antiviral agents

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2015, Acta pharmaceutica Sinica. B.

WITHDRAWN: Structure optimizations of the novel benzophenone derivatives as potential HIV-1 inhibitors

Xiaodong Ma, Yong-tang Zheng, Changyuan Wang, 2016 .

Benzophenone Derivatives : a Novel Scaffold as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Xiaodong Ma, Jiasheng Xu, Zhendong Song, 2016 .

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Xiaodong Ma, Q. Meng, Changyuan Wang, 2017, European journal of medicinal chemistry.

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Xiaodong Ma, Yue Jin, Xu Han, 2016, European journal of medicinal chemistry.

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Xiaodong Ma, Youwen Zhou, Changyuan Wang, 2016, Journal of medicinal chemistry.

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Jinyong Peng, Xiaodong Ma, Yue Jin, 2016, Bioorganic & medicinal chemistry.

Novel Selective and Potent EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Non-Small Cell Lung Cancer

Xiaodong Ma, Yue Jin, Zeyao Tang, 2016, Molecules.

Targeting mutated GTPase KRAS in tumor therapies.

Xiao-Feng Xiong, Xiaolei Zhang, Linlin Lou, 2021, European journal of medicinal chemistry.

Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis.

Guohui Wan, Xiao-Feng Xiong, Yi-You Huang, 2022, Journal of medicinal chemistry.

Silanol: a bifunctional group for peptide synthesis and late-stage functionalization†

A. Chan, Xiao-Feng Xiong, Zhendong Song, 2020, Chemical science.

Demethylative Alkylation of Methionine Residue by Employing the Sulfonium as the Key Intermediate.

A. Chan, Xiao-Feng Xiong, Zhendong Song, 2021, Organic Letters.

Synthesis and evaluation of imidazo[1,2-a]pyrazine derivatives as small molecule Gαq/11 inhibitors against uveal melanoma.

Xiao-Feng Xiong, Zhendong Song, Yang Ge, 2022, European journal of medicinal chemistry.

Discovery of novel indazole derivatives as SOS1 agonists that activate KRAS signaling.

Xiao-Feng Xiong, Xiaolei Zhang, Linlin Lou, 2023, Bioorganic & medicinal chemistry.