Zhulin Tan

发表

Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.

Jinhua J. Song, Bing-Shiou Yang, Jun Wang, 2016, Journal of the American Chemical Society.

Synthesis of p38 MAP kinase inhibitor BIRB 796 and analogs via copper-mediated N-arylation reaction

Jinhua J. Song, N. Yee, Daniel R Fandrick, 2010 .

Asymmetric methallylation of ketones catalyzed by a highly active organocatalyst 3,3'-F2-BINOL.

Jinhua J. Song, Jun Wang, C. Senanayake, 2013, Organic letters.

Efficient Iron‐Catalyzed Kumada Cross‐Coupling Reactions Utilizing Flow Technology under Low Catalyst Loadings

Jinhua J. Song, Bing-Shiou Yang, C. Senanayake, 2016 .

A highly convergent and efficient synthesis of a macrocyclic hepatitis C virus protease inhibitor BI 201302.

C. Senanayake, Xudong Wei, N. Yee, 2013, Organic letters.

Copper catalyzed asymmetric propargylation of aldehydes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Journal of the American Chemical Society.

Zinc catalyzed and mediated propargylations with propargyl boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

Zinc catalyzed and mediated asymmetric propargylation of trifluoromethyl ketones with a propargyl boronate.

Jinhua J. Song, B. Narayanan, C. Senanayake, 2013, The Journal of organic chemistry.

Achieving synthetic efficiency through new method development

Jinhua J. Song, C. Senanayake, N. Yee, 2008 .

Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ

Jinhua J. Song, S. Venkatraman, C. Senanayake, 2022, Organic Process Research & Development.

Organometallic methods for the synthesis and functionalization of azaindoles.

Fabrice Gallou, Jinhua J. Song, C. Senanayake, 2007, Chemical Society reviews.

Direct titanium-mediated conversion of ketones into enamides with ammonia and acetic anhydride.

C. Senanayake, Shengli Ma, Heewon Lee, 2012, Angewandte Chemie.

Development of an Asymmetric Route for Large-Scale Synthesis of a Glucocorticoid Agonist

Jinhua J. Song, Bing-Shiou Yang, C. Senanayake, 2016 .

Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.

Jinhua J. Song, B. Narayanan, C. Senanayake, 2013, The Journal of organic chemistry.

One-step construction of 2-substituted-4,6-diazaindoles from carboxylic acid derivatives

Jinhua J. Song, C. Senanayake, N. Yee, 2009 .

Practical regioselective bromination of azaindoles and diazaindoles

Jinhua J. Song, C. Senanayake, F. Gallou, 2007 .

Regioselective halogenation of 6-azaindoles : Efficient synthesis of 3-halo-2,3-disubstituted-6-azaindole derivatives

Jinhua J. Song, C. Senanayake, F. Gallou, 2005 .

A novel one-step synthesis of 2-substituted 6-azaindoles from 3-amino-4-picoline and carboxylic esters.

Jinghua Xu, Fabrice Gallou, Jinhua J. Song, 2005, The Journal of organic chemistry.

Double nucleophilic addition. A new one-pot synthesis of 2-alkyl- and 2-phenyl-5-hydrazinopyridine from pyridine

Zhulin Tan, Lin-hua Zhang, 2000 .

N-heterocyclic carbene-catalyzed silyl enol ether formation.

Jinhua J. Song, C. Senanayake, N. Yee, 2008, Organic letters.

N-heterocyclic carbene-catalyzed Mukaiyama aldol reactions.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Development of an Enantioselective Hydrogenation Route to (S)-1-(2-(Methylsulfonyl)pyridin-4-yl)propan-1-amine

Jinhua J. Song, Bing-Shiou Yang, C. Senanayake, 2014 .

A Practical Procedure for Reduction of Primary, Secondary and Tertiary Amides to Amines

C. Senanayake, Heewon Lee, B. Lu, 2013 .

Copper-catalyzed annulation of 2-formylazoles with o-aminoiodoarenes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, The Journal of organic chemistry.

Synthesis of P-Chiral Dihydrobenzooxaphosphole Core for BI Ligands in Asymmetric Transformations.

C. Senanayake, Xudong Wei, N. Yee, 2017, The Journal of organic chemistry.

N-heterocyclic carbene-catalyzed Mukaiyama aldol reactions.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Activation of TMSCN by N-heterocyclic carbenes for facile cyanosilylation of carbonyl compounds.

Jinhua J. Song, C. Senanayake, F. Gallou, 2006, The Journal of organic chemistry.

Highly diastereoselective zinc-catalyzed propargylation of tert-butanesulfinyl imines.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

Regioselective allene synthesis and propargylations with propargyl diethanolamine boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2009, Organic letters.

Carbamoyl anion addition to N-sulfinyl imines: highly diastereoselective synthesis of α-amino amides.

C. Senanayake, K. Fandrick, Shengli Ma, 2013, Journal of the American Chemical Society.

Development of a Practical Synthesis of 4-[6-(Morpholinomethyl)-pyridin-3-yl]naphthalen-1-amine, a Key Intermediate for the Synthesis of BIRB 1017, a Potent p38 MAP Kinase Inhibitor

Jinhua J. Song, C. Senanayake, N. Yee, 2013 .

Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Jinhua J. Song, B. Narayanan, Bing-Shiou Yang, 2017 .

Copper‐Catalyzed Annulation of 2‐Formylazoles with Aminoiodopyrazoles: Synthesis of New Heterocyclic Ring Systems

C. Senanayake, B. Lu, Zhulin Tan, 2013 .

Copper‐Catalyzed Annulation of 2‐Formylazoles with o‐Aminoiodoarenes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010 .

Mild and general zinc-alkoxide-catalyzed allylations of ketones with allyl pinacol boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

An Enantioselective Synthesis of an 11-β-HSD-1 Inhibitor via an Asymmetric Methallylation Catalyzed by (S)-3,3'-F2-BINOL.

Jiang-Ping Wu, Jun Wang, C. Senanayake, 2016, The Journal of organic chemistry.

Direct conversion of primary and secondary carboxylic acids to trifluoromethyl ketones

Jinhua J. Song, C. Senanayake, F. Gallou, 2007 .

Acid-promoted SN1/E1 fragmentation/dimerization of 2-cumylmalonates

Jinhua J. Song, C. Senanayake, N. Yee, 2009 .

Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl Grignard reagents.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

N-heterocyclic carbene catalyzed trifluoromethylation of carbonyl compounds.

Jinhua J. Song, C. Senanayake, F. Gallou, 2005, Organic letters.

A general synthesis of substituted formylpyrroles from ketones and 4-formyloxazole.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Development of a preparative-scale asymmetric synthesis of (R)-p-tolyl methyl sulfoxide for use in a one-pot synthesis of a drug intermediate containing a trifluoromethyl-substituted alcohol functionality

Jinhua J. Song, C. Senanayake, N. Yee, 2007 .

Scalable Process of Spiro(cyclopropane)oxazepane Pyridine Carboxylic Acid through Kulinkovich, Mitsunobu, and Pd-Catalyzed Intramolecular C–N Coupling

Jinhua J. Song, C. Senanayake, B. Qu, 2022, Organic Process Research & Development.

Start selective and rigidify: The discovery path towards a next generation of EGFR tyrosine kinase inhibitors.

Julian E. Fuchs, P. Ettmayer, A. Baum, 2019, Journal of medicinal chemistry.

Preparative Synthesis via Continuous Flow of 4,4,5,5-Tetramethyl-2-(3-trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane: A General Propargylation Reagent

Jinhua J. Song, C. Senanayake, J. T. Reeves, 2012 .

Discovery and optimization of p38 inhibitors via computer-assisted drug design.

Angela Berry, Jinhua J. Song, Ming-Hong Hao, 2007, Journal of medicinal chemistry.

Synthesis of 5-bromopyridyl-2-magnesium chloride and its application in the synthesis of functionalized pyridines.

Jinhua J. Song, C. Senanayake, Jinghua Xu, 2004, Organic Letters.

Synthesis of 5‐Bromopyridyl‐2‐magnesium Chloride and Its Application in the Synthesis of Functionalized Pyridines

Jinhua J. Song, C. Senanayake, Jinghua Xu, 2005 .

Process safety evaluation of a magnesium : Iodine exchange reaction

Jinhua J. Song, C. Senanayake, N. Yee, 2006 .

1,3‐Di‐tert‐butylimidazol‐2‐ylidene

Jinhua J. Song, C. Senanayake, N. Yee, 2008 .

Development of an Asymmetric Acetate Aldol Reaction with a Trifluoromethyl Ketone

Jinhua J. Song, C. Senanayake, Jinghua Xu, 2007 .

Trifluoromethyl ketones from enolizable carboxylic acids via enediolate trifluoroacetylation/decarboxylation.

Jinhua J. Song, C. Senanayake, N. Yee, 2008, The Journal of organic chemistry.

Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 2: Asymmetric Synthesis via Shi Epoxidation

Jinhua J. Song, F. Buono, Jon C. Lorenz, 2024, Organic Process Research & Development.