Kaiming Tang

发表

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

K. To, C. Yip, Jian-Piao Cai, 2022, Science.

The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model

K. To, C. Yip, Jian-Piao Cai, 2022, bioRxiv.

Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo

Shuofeng Yuan, Z. Ye, B. Dang, 2022, Cell Research.

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells

J. Chan, K. Yuen, H. Chu, 2020, Metabolites.

The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Emerging microbes & infections.

Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters.

Jian-Piao Cai, Kwok-Hung Chan, Cuiting Luo, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Targeting papain-like protease for broad-spectrum coronavirus inhibition

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Protein & Cell.

Cross-variant protection against SARS-CoV-2 infection in hamsters immunized with monovalent and bivalent inactivated vaccines

K. To, Cuiting Luo, J. Chan, 2022, International journal of biological sciences.

Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Pharmaceuticals.

Development of highly potent non-covalent inhibitors of SARS-CoV-2 3CLpro

Vineet D. Menachery, Xuping Xie, P. Shi, 2022, bioRxiv.

Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system

Jian-Piao Cai, Lin-Lei Chen, J. Chan, 2020, Pharmacological Research.

Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

Ronald A. Li, S. Chanda, R. Sun, 2021, Nature.

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

K. To, Jian-Piao Cai, J. Chan, 2020, Viruses.

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection

Jian-Piao Cai, J. Chan, K. Yuen, 2021, Emerging microbes & infections.

A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters

K. To, Jian-Piao Cai, J. Chan, 2021, Emerging microbes & infections.

Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets

J. Chan, K. Yuen, H. Chu, 2021, Computational and structural biotechnology journal.

In Silico Structure-Based Design of Antiviral Peptides Targeting the Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein Gn

Jian-Piao Cai, Cuiting Luo, J. Chan, 2021, Viruses.

Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals

K. To, Cuiting Luo, J. Chan, 2022, Cellular & Molecular Immunology.

Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection

P. Chiu, Cheuk-Lun Lee, W. Yeung, 2022, bioRxiv.

Long SARS-CoV-2 nucleocapsid sequences in blood monocytes collected soon after hospital admission

Kwok-Hung Chan, Kaiming Tang, K. To, 2020, bioRxiv.

Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta Variant

Jie Zhou, Lu Lu, Shuofeng Yuan, 2022, Viruses.

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility

K. To, Jian-Piao Cai, W. Chan, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication

K. To, Cuiting Luo, J. Chan, 2021, Cell Discovery.

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication

K. To, Jian-Piao Cai, Cuiting Luo, 2021, Cell discovery.

Inhaled Dry Powder Formulation of Tamibarotene, a Broad‐Spectrum Antiviral against Respiratory Viruses Including SARS‐CoV‐2 and Influenza Virus

J. Chan, K. Yuen, Shuofeng Yuan, 2021, Advanced Therapeutics.

Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

S. Chanda, R. Sun, K. To, 2020, Research square.

Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target

Shuofeng Yuan, Meitian Wang, S. Aumonier, 2023, Nature communications.

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor

Jian-Piao Cai, Cuiting Luo, J. Chan, 2021, International journal of biological sciences.

Comparative analysis of SARS‐CoV‐2 Omicron BA.2.12.1 and BA.5.2 variants

J. Chan, H. Chu, Shuofeng Yuan, 2022, Journal of medical virology.

Broad-spectrum humanized monoclonal neutralizing antibody against SARS-CoV-2 variants, including the Omicron variant

K. To, Jian-Piao Cai, Lin-Lei Chen, 2023, Frontiers in cellular and infection microbiology.

Impact of Pb on Chlamydomonas reinhardtii at Physiological and Transcriptional Levels

Nan Huang, Xiaojuan Liu, M. Aslam, 2020, Frontiers in Microbiology.

Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro

Vineet D. Menachery, Xuping Xie, P. Shi, 2023, ACS central science.

Metal-coding assisted serological multi-omics profiling deciphers the role of selenium in COVID-19 immunity

A. Tam, Cuiting Luo, Shuofeng Yuan, 2023, Chemical Science.

Monovalent vaccination with inactivated SARS-CoV-2 BA.5 protects hamsters against Omicron but not non-Omicron variants

Shuofeng Yuan, Pak-Hin Hinson Cheung, C. P. Ong, 2023, NPJ vaccines.

Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase

Shuofeng Yuan, Ying Zhou, Kaiming Tang, 2024, Chemical Science.

Identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics

Jian-Piao Cai, W. Chan, Shuofeng Yuan, 2024, Acta Pharmaceutica Sinica B.

PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness

Shuofeng Yuan, F. Yin, Jianli Cao, 2024, Nature communications.

SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

Shuofeng Yuan, Ryohichi Sugimura, Degong Ruan, 2024, bioRxiv.

An enhanced broad-spectrum peptide inhibits Omicron variants in vivo

W. DeGrado, Shuofeng Yuan, B. Dang, 2024, Cell reports. Medicine.

Integration of metalloproteome and immunoproteome reveals a tight link of iron-related proteins with COVID-19 pathogenesis and immunity.

Cuiting Luo, Shuofeng Yuan, Ying Zhou, 2024, Clinical immunology.

Alisol B 23-acetate broadly inhibits coronavirus through blocking virus entry and suppresses proinflammatory T cells responses for the treatment of COVID-19

Shuofeng Yuan, Meiling Wu, Qiaohui Du, 2023, Journal of advanced research.