P. Théroux

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Utilization of catheterization and revascularization procedures in patients with non‐ST segment elevation acute coronary syndrome over the last decade

C. Cannon, K. Mahaffey, G. Levine, 2005, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Evaluation and risk stratification of acute coronary syndromes using a low cut-off level of cardiac troponin T, combined with CK-MB mass determination.

M. Bourassa, P. Théroux, A. Fortier, 2004, Clinical biochemistry.

Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes. Gradient of benefit related to the revascularization strategy.

Deepak L. Bhatt, E. Topol, H. White, 2002, European heart journal.

Left main stenting–as a bridge to surgery–for acute type A aortic dissection and anterior myocardial infarction

R. Petitclerc, R. Cartier, P. Théroux, 2000, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Combining enoxaparin and glycoprotein IIb/IIIa antagonists for the treatment of acute coronary syndromes: final results of the National Investigators Collaborating on Enoxaparin-3 (NICE-3) study.

E. Antman, R. Harrington, C. Pepine, 2003, American heart journal.

Efficacy and Safety of Ticagrelor Over Time in Patients With Prior MI in PEGASUS-TIMI 54.

Marc P. Bonaca, Deepak L. Bhatt, A. Parkhomenko, 2017, Journal of the American College of Cardiology.

Complementary prognostic values of ST segment deviation and Thrombolysis In Myocardial Infarction (TIMI) risk score in non-ST elevation acute coronary syndromes: Insights from the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-P

R. Giugliano, P. Théroux, T. Luong, 2009, The Canadian journal of cardiology.

Quantitative Angiographic Morphology of the Coronary Artery Lesions at Risk of Thrombotic Occlusion

D. Waters, P. Théroux, Y. Taeymans, 1992, Circulation.

New antithrombotics.

R. Califf, J. Weitz, Jeffrey S. Ginsberg, 1995, Chest.

Effects of tirofiban plus heparin versus heparin alone on troponin I levels in patients with acute coronary syndromes.

R. Giugliano, K. Lewandrowski, P. Théroux, 2000, The American journal of cardiology.

ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--2002: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients

Carl J Pepine, Joseph S Alpert, Robert M Califf, 2002, Circulation.

Clinical and angiographic factors associated with progression of coronary artery disease.

D. Waters, P. Finès, P. Théroux, 1984, Journal of the American College of Cardiology.

Vorapaxar in patients with coronary artery bypass grafting: Findings from the TRA 2°P-TIMI 50 trial

Marc P. Bonaca, E. Braunwald, D. Morrow, 2017, European heart journal. Acute cardiovascular care.

Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial

P. Armstrong, C. Granger, K. Mahaffey, 2012, Journal of Thrombosis and Thrombolysis.

B-type natriuretic peptide and the effect of ranolazine in patients with non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary-Thrombolysis In Myocardial Infarction 36) trial.

M. Sabatine, E. Braunwald, D. Morrow, 2010, Journal of the American College of Cardiology.

Clinical and angiographic features of coronary artery disease in young women

D. Waters, C. Halphen, P. David, 1978 .

Randomized, Double-Blind, Placebo-Controlled, International Trial of the Oral IIb/IIIa Antagonist Lotrafiban in Coronary and Cerebrovascular Disease

R. Califf, E. Topol, F. Van de Werf, 2003, Circulation.

Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial).

R. Califf, E. Topol, H. Diener, 2008, The American journal of cardiology.

Interactions between age, outcome of acute coronary syndromes, and tirofiban therapy.

M. Sabatine, P. Théroux, J. Januzzi, 2003, The American journal of cardiology.

Effects of nitroglycerin at therapeutic doses on platelet aggregation in unstable angina pectoris and acute myocardial infarction.

D. Waters, P. Théroux, J. Diodati, 1990, The American journal of cardiology.

Ventricular arrhythmias during ergonovine-induced episodes of variant angina.

D. Waters, D. Miller, P. Théroux, 1984, American heart journal.

ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction: A report of the american college of cardiology/ american heart association task force on practice guidelines (committee on the management of patients with unstable angina)

J. W. Schaeffer, R. Califf, E. Antman, 2000 .

Classification and risk stratification of patients with acute chest pain using a low discriminatory level of cardiac troponin T

M. Bourassa, P. Théroux, A. Fortier, 2004, Clinical cardiology.

Combination therapy with tirofiban and enoxaparin in acute coronary syndromes.

L. Deckelbaum, H. White, M. Cohen, 1999, International journal of cardiology.

ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients

Carl J Pepine, Joseph S Alpert, Robert M Califf, 2002, Journal of the American College of Cardiology.

Integrating ancillary studies in a large clinical trial: the design and rationale of the APEX library.

Manesh R. Patel, P. Armstrong, C. Granger, 2008, Contemporary clinical trials.

Early noninvasive identification of failed reperfusion after intravenous thrombolytic therapy in acute myocardial infarction.

H. White, K. Ramanathan, P. Théroux, 1998, Journal of the American College of Cardiology.

Progression of Coronary Atherosclerosis

D. Waters, R. Havel, G. Gosselin, 2005 .

Tirofiban therapy for patients with acute coronary syndromes and prior coronary artery bypass grafting in the PRISM-PLUS trial.

S. Snapinn, P. Théroux, J. Januzzi, 2004, The American journal of cardiology.

Randomized comparison of a novel anticoagulant, vasoflux, and heparin as adjunctive therapy to streptokinase for acute myocardial infarction: results of the VITAL study (Vasoflux International Trial for Acute Myocardial Infarction Lysis).

R. Peters, H. White, W. Weaver, 2001, American heart journal.

Atherosclerosis / Coronary Heart Disease Short-term Cholesterol Lowering Decreases Size and Severity of Perfusion Abnormalities by Positron Emission Tomography After Dipyridamole in Patients With Coronary Artery Disease : A Potential Noninvasive Marker of Healing Coronary Endothelium

V. Fuster, R. Califf, K. Dickstein, 2005 .

Effects of selective matrix metalloproteinase inhibitor (PG-116800) to prevent ventricular remodeling after myocardial infarction: results of the PREMIER (Prevention of Myocardial Infarction Early Remodeling) trial.

Mario J. Garcia, P. Armstrong, W. Weaver, 2006, Journal of the American College of Cardiology.

Meta-analysis of randomized trials comparing enoxaparin versus unfractionated heparin as adjunctive therapy to fibrinolysis in ST-elevation acute myocardial infarction.

R. Welsh, P. Théroux, P. Théroux, 2003, The American journal of cardiology.

2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in c

Hani Jneid, Robert M Califf, Charles R Bridges, 2011, Journal of the American College of Cardiology.

A first‐in‐man study of percutaneous myocardial cryotreatment in nonrevascularizable patients with refractory angina

B. Strauss, D. Stewart, P. Fefer, 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Heparin resistance in acute coronary syndromes

C. Cannon, J. Hirsh, P. Théroux, 2007, Journal of Thrombosis and Thrombolysis.

A randomized study comparing propranolol and diltiazem in the treatment of unstable angina.

D. Waters, P. Théroux, Y. Taeymans, 1985, Journal of the American College of Cardiology.

Action of nifedipine in ischemic heart disease.

D. Waters, D. Miller, P. Théroux, 1983, Canadian family physician Medecin de famille canadien.

Spontaneous remission is a frequent outcome of variant angina.

D. Waters, P. Théroux, A. Bouchard, 1983, Journal of the American College of Cardiology.

Comparative Sensitivity of Exercise, Cold Pressor and Ergonovine Testing in Provoking Attacks of Variant Angina in Patients with Active Disease

D. Waters, D. Miller, P. Théroux, 1982, Circulation.

Provocative testing with ergonovine to assess the efficacy of treatment with nifedipine, diltiazem and verapamil in variant angina.

D. Waters, P. Théroux, J. Szlachcic, 1981, The American journal of cardiology.

Ergonovine testing to detect spontaneous remissions of variant angina during long-term treatment with calcium antagonist drugs.

D. Waters, P. Théroux, J. Szlachcic, 1981, The American journal of cardiology.

S-T segment elevation and coronary spasm in response to exercise.

B. Chaitman, D. Waters, P. Théroux, 1981, The American journal of cardiology.

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

Judith S. Hochman, Eric D. Peterson, Robert M. Califf, 2011 .

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Judith S. Hochman, Eric D. Peterson, Robert M. Califf, 2011, Circulation.

Prognostic usefulness of white blood cell count and temperature in acute myocardial infarction (from the CARDINAL Trial).

Manesh R. Patel, P. Armstrong, W. Weaver, 2005, The American journal of cardiology.

Correlation between the TIMI risk score and high-risk angiographic findings in non-ST-elevation acute coronary syndromes: observations from the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) trial.

E. Antman, J. Mega, M. Sabatine, 2005, American heart journal.

ACC/AHA guidelines for the management of patients with unstable angina and non‐ST segment elevation myocardial infarction: Executive summary and recommendations

J. W. Schaeffer, V. Fuster, R. Califf, 2000, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

ACCF / AHA Focused Update 2012 ACCF / AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina / Non – ST-Elevation Myocardial Infarction ( Updating the 2007 Guideline and Replacing the 2011 Focused Update )

Judith S. Hochman, Eric D. Peterson, Hani Jneid, 2012 .

N-terminal pro-brain natriuretic peptide and the timing, extent and mortality in ST elevation myocardial infarction.

P. Armstrong, W. Weaver, C. Granger, 2006, The Canadian journal of cardiology.

Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial.

P. Armstrong, C. Granger, A. Stebbins, 2012, American heart journal.

ACCF/AHA Focused Update 2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/ Non–ST-Elevation Myocardial Infarction

R. Califf, E. Antman, Jeffrey L. Anderson, 2011 .

ACC/AHA guidelines for the management of patients with unstable angina and non‐ST segment elevation myocardial infarction: Executive summary and recommendations

J. W. Schaeffer, R. Califf, E. Antman, 2000, Circulation.

2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Nancy M Albert, Hani Jneid, Robert M Califf, 2013, Journal of the American College of Cardiology.

Hemodynamics and coronary flow following diltiazem administration in anesthetized dogs and in humans.

D. Waters, M. Bourassa, P. Théroux, 1980, Chest.

Provocative Testing with Ergonovine to Evaluate the Efficacy of Treatment with Calcium Antagonists in Variant Angina

D. Waters, P. Théroux, J. Crittin, 1979, Circulation.

Coronary angiographic significance of left anterior fascicular block during acute myocardial infarction.

D. Waters, X. Bosch, D. Roy, 1985, Journal of the American College of Cardiology.

Effect of Pexelizumab, an Anti-C5 Complement Antibody, as Adjunctive Therapy to Fibrinolysis in Acute Myocardial Infarction: The COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) Trial

P. Armstrong, W. Weaver, C. Granger, 2003, Circulation.

Platelet Glycoprotein IIb/IIIa Receptor Inhibition in Non–ST-Elevation Acute Coronary Syndromes Early Benefit During Medical Treatment Only, With Additional Protection During Percutaneous Coronary Intervention Brief Rapid Communication

R. Califf, E. Topol, M. Simoons, 1999 .

Oral inhibitors of platelet membrane receptor glycoprotein IIb/IIIa in clinical cardiology: issues and opportunities.

P. Théroux, P. Théroux, 1998, American heart journal.

Randomized double-blind comparison of two doses of Hirulog with heparin as adjunctive therapy to streptokinase to promote early patency of the infarct-related artery in acute myocardial infarction.

D. Waters, P. Théroux, F. Pérez-Villa, 1995, Circulation.

Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts following percutaneous transluminal coronary angioplasty.

P. Stein, J. Dalen, P. Théroux, 1992, Chest.

Initial Experience Witha Direct Antithrombin, Hirulog, inUnstable Angina Anticoagulant, Antithrombotic, andClinical Effects

M. Juneau, R. Lidón, P. Théroux, 1993 .

Antiplatelet and antithrombotic therapy in unstable angina.

P. Théroux, 1991, The American journal of cardiology.

Antithrombotic agents in coronary artery disease.

J. Cairns, P. Théroux, G. Sutton, 1995, Chest.

Five- to ten-year outcome after multivessel percutaneous transluminal coronary angioplasty.

R. Bonan, G. Côté, C. le Feuvre, 1993, The American journal of cardiology.

Left main coronary artery stenosis in young patients.

D. Waters, P. Théroux, J. Crittin, 1979, Chest.

Clopidogrel inhibits platelet-leukocyte interactions and thrombin receptor agonist peptide-induced platelet activation in patients with an acute coronary syndrome.

P. Théroux, Zihui Xiao, P. Théroux, 2004, Journal of the American College of Cardiology.

Chronic oral vasodilator therapy to control heart failure in postinfarction ventricular septal defect.

D. Waters, G. Pelletier, D. Phaneuf, 1979, Catheterization and cardiovascular diagnosis.

Avoiding interpretive pitfalls when assessing arrhythmia suppression after myocardial infarction: insights from the long-term observations of the placebo-treated patients in the Cardiac Arrhythmia Pilot Study (CAPS)

J. Myles, J. Coromilas, P. Théroux, 1991, Journal of the American College of Cardiology.

Effects of diltiazem on atrioventricular conduction and arterial blood pressure: correlation with plasma drug concentrations.

P. Théroux, J. Billette, R. Cartier, 1984, Canadian journal of physiology and pharmacology.

Sinus Node Dysfunction and Sudden Cardiac Death Following Treatment with Encainide

S. Nattel, P. Théroux, M. Talajic, 1989, Pacing and clinical electrophysiology : PACE.

Long-term Tolerability of Ticagrelor for the Secondary Prevention of Major Adverse Cardiovascular Events: A Secondary Analysis of the PEGASUS-TIMI 54 Trial.

Marc P. Bonaca, Deepak L. Bhatt, M. Sabatine, 2016, JAMA cardiology.

Antiplatelet therapy: do the new platelet inhibitors add significantly to the clinical benefits of aspirin?

P. Théroux, P. Théroux, 1997, American heart journal.

Prognostic significance of blood markers of inflammation in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty and effects of pexelizumab, a C5 inhibitor: a substudy of the COMMA trial.

J. Burchenal, P. Armstrong, C. Granger, 2005, European heart journal.

Influence of Renal Function on the Efficacy and Safety of Fondaparinux Relative to Enoxaparin in NonST-Segment Elevation Acute Coronary Syndromes

S. Yusuf, L. Piegas, S. Mehta, 2007, Annals of Internal Medicine.

Whither the coronary care unit?

D. Waters, P. Théroux, 1987, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial

H. White, B. Chaitman, J. Schroeder, 2000, Current Controlled Trials in Cardiovascular Medicine.

Lipoprotein (a) blood levels in unstable angina pectoris, acute myocardial infarction, and after thrombolytic therapy.

J. Genest, M. Marcil, D. Robitaille, 1991, The American journal of cardiology.

A heparin-controlled study of MK-383 in unstable angina

F. Werf, C. Nienaber, P. Théroux, 1994 .

Acute Coronary Syndromes: A Companion to Braunwald's Heart Disease

P. Théroux, P. Théroux, 2003 .

Title : Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

R. Califf, B. Lewis, R. Giugliano, 2022 .

Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study.

B. Lewis, M. Sabatine, E. Braunwald, 2005, JAMA.

Increased mortality after coronary artery bypass graft surgery is associated with increased levels of postoperative creatine kinase-myocardial band isoenzyme release: results from the GUARDIAN trial.

B. Chaitman, P. Théroux, A. Jessel, 2001, Journal of the American College of Cardiology.

Determinants of hemorrhagic infarcts. Histologic observations from experiments involving coronary occlusion, coronary reperfusion, and reocclusion.

F. Fernández‐Avilés, D. Garcia-Dorado, J. Alonso, 1990, The American journal of pathology.

Favorable effects of hyperosmotic reperfusion on myocardial edema and infarct size.

F. Fernández‐Avilés, P. Théroux, D. Garcia-Dorado, 1992, The American journal of physiology.

Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.

D. Waters, P. Théroux, J. Diodati, 1990, The American journal of cardiology.

Analysis of bleeding complications associated with glycoprotein IIb/IIIa receptors blockade in patients with high-risk acute coronary syndromes: insights from the PRISM-PLUS study.

S. Snapinn, P. Théroux, T. Huynh, 2005, International journal of cardiology.

2011 ACCF/AHA focused update of the Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (updating the 2007 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in

Hani Jneid, Robert M Califf, Charles R Bridges, 2011, Journal of the American College of Cardiology.

Exercise stress testing in the post-myocardial infarction patient.

M. Bourassa, D. Marpole, P. Théroux, 1983, The American journal of cardiology.

Prognostic Value of Limited Exercise Testing before Hospital Discharge Following Myocardial Infarction

D. Waters, P. Théroux, 1981 .

Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study.

B. Lewis, M. Sabatine, E. Braunwald, 2005, JAMA.

Usefulness of tirofiban among patients treated without percutaneous coronary intervention (TIMI high risk patients in PRISM-PLUS).

E. Antman, M. Sabatine, E. Braunwald, 2004, The American journal of cardiology.

Ergonovine testing in a coronary care unit.

D. Waters, J. Szlachcic, R. Bonan, 1980, The American journal of cardiology.

A randomized placebo-controlled trial to assess the efficacy of antiinflammatory therapy with methylprednisolone in unstable angina (MUNA trial).

P. Stone, D. Waters, A. Wu, 2000, European heart journal.

Influence of functional deficiency of complement mannose-binding lectin on outcome of patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.

M. Pfisterer, P. Armstrong, C. Granger, 2010, European heart journal.

Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease.

G. FitzGerald, P. Théroux, B. Rocca, 2001, The American journal of cardiology.

Long-term prognosis after myocardial infarction in patients with previous coronary artery bypass surgery.

D. Waters, P. Théroux, D. Roy, 1988, Journal of the American College of Cardiology.

Early postinfarction ischemia: clinical, angiographic, and prognostic significance.

D. Waters, P. Théroux, X. Bosch, 1987, Circulation.

Epoprostenol (Prostacyclin) in Unstable Angina

E. Rapaport, P. Théroux, J. Willerson, 1988, Journal of clinical pharmacology.

Plasma endothelin-1 levels in stable and unstable angina.

P. Théroux, M. Marcil, B. Solymoss, 1993, Cardiology.

Refractory variant angina controlled with combined drug therapy in a patient with a single coronary artery.

D. Waters, G. Pelletier, D. Phaneuf, 1980, Catheterization and cardiovascular diagnosis.

Modulation of Platelet-neutrophil Interaction with Pharmacological Inhibition of Fibrinogen Binding to Platelet GPIIb/IIIa Receptor

P. Théroux, M. Frojmovic, Zihui Xiao, 1999, Thrombosis and Haemostasis.

Pathophysiology of Unstable Angina Pectoris: Clinical, Angiographic and Therapeutic Observations

D. Waters, P. Théroux, Y. Taeymans, 1988 .

Clinical characteristics of patients with variant angina complicated by myocardial infarction or death within 1 month.

D. Waters, D. Miller, P. Théroux, 1982, The American journal of cardiology.

Point-of-Care Measured Platelet Inhibition Correlates With a Reduced Risk of an Adverse Cardiac Event After Percutaneous Coronary Intervention: Results of the GOLD (AU-Assessing Ultegra) Multicenter Study

P. Teirstein, S. Steinhubl, G. Dangas, 2001, Circulation.

Recurrence of Prinzmetal angina seven years following aortocoronary bypass surgery: a clinical and angiographic follow-up.

D. Waters, J. Crittin, J. Lésperance, 1979, Catheterization and cardiovascular diagnosis.

Platelet Glycoprotein IIb/IIIa Inhibitors Reduce Mortality in Diabetic Patients With Non–ST-Segment-Elevation Acute Coronary Syndromes Clinical Investigation and Reports

Deepak L. Bhatt, R. Califf, E. Topol, 2001 .

Effects of P2Y1 receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel

A. Bonnefoy, M. Bryckaert, B. Labarthe, 2012, British journal of pharmacology.

Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial. OASIS Pilot Study Investigators. Organization to Assess Strategies for Ischemic++ Syndromes.

S. Yusuf, J. Pogue, M. Flather, 2000, European heart journal.

Redefining medical treatment in the management of unstable angina.

V. Fuster, R. Califf, E. Topol, 2011, The American journal of medicine.

Troponin I levels in unstable angina/non-Q wave myocardial infarction patients treated with tirofiban, a glycoprotein IIb/IIIa antagonist

R. Giugliano, K. Lewandrowski, P. Théroux, 1998 .

The delay to thrombolysis: an analysis of patient and hospital characteristics

J. Brophy, P. Théroux, J. Diodati, 1998 .

Determinants of Hemorrhagic Infarcts

D. Garcia-Dorado, J. Alonso, J. Elízaga, 2007 .

Requirements for Membrane Attack Complex Formation and Anaphylatoxins Binding to Collagen-Activated Platelets

P. Théroux, P. Maurice, A. Bonnefoy, 2011, PloS one.

Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts.

P. Stein, J. Dalen, S. Goldman, 1995, Chest.

Design of the blockade of the glycoprotein IIb/IIIa receptor to avoid vascular occlusion (BRAVO) trial.

R. Califf, E. Topol, F. Van de Werf, 2000, American heart journal.

Cardiovascular findings in arterial tortuosity syndrome

C. Cannon, C. McCabe, J. López-Sendón, 2015 .

significance Early postinfarction ischemia: clinical, angiographic, and prognostic

D. Waters, X. Bosch, D. Roy, 2011 .

Sulfinpyrazone decreases epinephrine-induced platelet aggregation after myocardial infarction.

M. Bourassa, J. Latour, P. Théroux, 1982, American Journal of Cardiology.

UNSTABLE ANGINA Fibrinopeptide A and platelet factor levels in unstable angina pectoris

P. Théroux, J. Latour, C. LEGER-GAUTHIER, 2005 .

Cholesterol Reduction Rapidly Improves Endothelial Function After Acute Coronary Syndromes

J. Tardif, P. Théroux, J. Dupuis, 1998 .

Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials

R. Califf, E. Topol, P. Armstrong, 2002, The Lancet.

Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations main results of the guard during ischemia against necrosis (GUARDIAN) trial

B. Chaitman, P. Théroux, N. Danchin, 2001 .

Cell-to-cell interaction: a mechanism to explain wave-front progression of myocardial necrosis.

F. Fernández‐Avilés, M. Desco, P. Théroux, 1989, The American journal of physiology.

Regional myocardial function early and during the healing of acute myocardial infarction

J. Ross, C. Bloor, D. Franklin, 1975 .

Antithrombotic Therapy in Patients WithSaphenous Vein andInternal Mammary Artery Bypass Grafts

P. Théroux, S. Goldman, L. Schwartz, 2015 .

Prostaglandin E1 increases myocardial contractility in the conscious dog.

M. Bourassa, S. Roux, J. Clozel, 1984, Canadian journal of physiology and pharmacology.

Glycoprotein IIb/IIIa Receptor Blockade Improves Outcomes in Diabetic Patients Presenting With Unstable Angina/Non–ST-Elevation Myocardial Infarction: Results From the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study

S. Snapinn, P. Théroux, E. Barr, 2000, Circulation.

Antithromboric agents in coronary artery disease

J. Cairns, J. Hirsh, L. Resnekov, 1992 .

Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation.

A. Skene, M. Sabatine, E. Braunwald, 2005, The New England journal of medicine.

2012 ACCF/AHA focused update of the guideline for the management of patients with unstable angina/non-ST-elevation myocardial infarction (updating the 2007 guideline and replacing the 2011 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Forc

Hani Jneid, Charles R Bridges, Theodore G Ganiats, 2012, Journal of the American College of Cardiology.

Previous coronary artery bypass grafting as an adverse prognostic factor in unstable angina pectoris.

D. Waters, P. Théroux, Denis Roy, 1986, The American journal of cardiology.

Comparison of outcome of patients with unstable angina and non-Q-wave acute myocardial infarction with and without prior coronary artery bypass grafting (Thrombolysis in Myocardial Ischemia III Registry).

P. Stone, W. Rogers, H. Anderson, 1996, The American journal of cardiology.

Effect of platelet glycoprotein IIb/IIIa receptor blockade with tirofiban on adverse cardiac events in women with unstable angina/non-ST-elevation myocardial infarction (PRISM-PLUS Study).

S. Snapinn, P. Théroux, T. Huynh, 2003, American heart journal.

Improved long-term clinical outcomes in unstable angina-patients undergoing coronary angioplasty following therapy with tirofiban and heparin

S. Snapinn, P. Théroux, E. Barr, 1998 .

Regional Myocardial Function during Acute Coronary Artery Occlusion and Its Modification by Pharmacologic Agents in the Dog

D Franklin, J Ross, J. Ross, 1974, Circulation research.

A pathophysiologic basis for the clinical classification and management of unstable angina.

P. Théroux, P. Théroux, 1987, Circulation.

Glycoprotein IIb/IIIa Receptor Blockade Improves Outcomes in Diabetic Patients Presenting With Unstable Angina/Non–ST-Elevation Myocardial Infarction Results From the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Cl

S. Snapinn, P. Théroux, E. Barr, 2000 .

Unstable angina: pathogenesis, diagnosis, and treatment.

P. Théroux, R. Lidón, P. Théroux, 1993, Current problems in cardiology.

Antithrombin-III plasma activity during and after prolonged use of heparin in unstable angina.

P. Théroux, R. Lidón, D. Robitaille, 1993, Thrombosis research.

Pharmacologic therapy of myocardial ischemia

R. Lidón, P. Théroux, 1992 .

Long-term prognosis of patients with variant angina.

D. Waters, D. Miller, P. Théroux, 1987, Circulation.

Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor.

P Théroux, P. Théroux, Z Xiao, 1998, Circulation.

Clinical outcomes of bivalirudin for ischemic heart disease.

V. Hasselblad, R. Califf, E. Topol, 1999, Circulation.

Regional Myocardial function in the conscious dog during acute coronary occlusion and responses to morphine, propranolol, nitroglycerin, and lidocaine.

P. Théroux, J. Ross, W S Kemper, 1976 .

2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

R. Califf, E. Antman, Jeffrey L. Anderson, 2013, Circulation.

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patie

J. Ornato, R. Califf, E. Antman, 2007, Journal of the American College of Cardiology.

Prognostic value of exercise testing soon after myocardial infarction.

D. Waters, P. Théroux, C. Halphen, 1979, The New England journal of medicine.

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

Walker, R. Collins, V. Fuster, 1994 .

The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society guidelines.

J. Douketis, N. Pannu, R. Welsh, 2011, The Canadian journal of cardiology.

The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society Guidelines Executive Summary.

J. Douketis, N. Pannu, R. Welsh, 2011, The Canadian journal of cardiology.

High-performance liquid chromatographic determination of diltiazem and six of its metabolites in human urine.

P. Théroux, P. Biron, Y. Taeymans, 1984, Journal of pharmaceutical sciences.

Protection of the myocardial cell during ischemia.

P. Théroux, P. Théroux, 1999, The American journal of cardiology.

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.

R. Califf, B. Lewis, R. Giugliano, 2015, The New England journal of medicine.

Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug.

P. Théroux, M. Angioï, B. Labarthe, 2005, Journal of the American College of Cardiology.

Long-term use of ticagrelor in patients with prior myocardial infarction.

Marc P. Bonaca, Deepak L. Bhatt, M. Sabatine, 2015, The New England journal of medicine.

Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy.

V. Hasselblad, P. Armstrong, C. Granger, 2013, International journal of cardiology.

Pathophysiology of Coronary Artery Disease

P. Libby, P. Théroux, P. Théroux, 2005, Circulation.

Influence of race, sex, and age on management of unstable angina and non-Q-wave myocardial infarction: The TIMI III registry.

E. Braunwald, P. Stone, W. Rogers, 1996 .

Coronary artery disease in young women: clinical and angiographic features and correlation with risk factors.

D. Waters, P. Théroux, C. Halphen, 1978, The American journal of cardiology.

Is variant angina the coronary manifestation of a generalized vasospastic disorder?

D. Waters, D. Miller, P. Théroux, 1981, The New England journal of medicine.

Rationale and design of the LosmApimod To Inhibit p38 MAP kinase as a TherapeUtic target and moDify outcomes after an acute coronary syndromE trial.

M. Sabatine, D. Morrow, J. López-Sendón, 2015, American heart journal.

Progress in the treatment of acute coronary syndromes: a 50-year perspective (1950-2000).

P. Armstrong, P. Théroux, J. Willerson, 2000, Circulation.

Clinical and angiographic features and prognostic significance of early postinfarction angina with and without electrocardiographic signs of transient ischemia.

D. Waters, G. Sanz, P. Théroux, 1991, The American journal of medicine.

Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin

M. Dubé, Q. Duan, G. Rouleau, 2006, Psychosomatic medicine.

Regional Myocardial Function in the Conscious Dog During Acute Coronary Occlusion and Responses to Morphine, Propranolol, Nitroglycerin, and Lidocaine

J. Ross, S. Sasayama, P. Théroux, 1976, Circulation.

Depression and 1-year prognosis in unstable angina.

N. Frasure-smith, F. Lespérance, P. Théroux, 2000, Archives of internal medicine.

A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis.

P Théroux, D. Waters, R. Havel, 1990, Circulation.

Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction.

Robert Lemery, M Huther, D Brill, 1992, The New England journal of medicine.

Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial.

J. Tardif, P. Théroux, J. Dupuis, 1999, Circulation.

2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/ Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

R. Califf, E. Antman, V. Chair, 2011, Circulation.

Late development of left ventricular outflow tract obstruction after repair of double-outlet right ventricle.

B. Chaitman, M. Bourassa, P. Théroux, 1976, The Journal of thoracic and cardiovascular surgery.

Vorapaxar in the secondary prevention of atherothrombotic events.

Marc P. Bonaca, E. Braunwald, D. Morrow, 2012, The New England journal of medicine.

Spontaneous variability of ventricular arrhythmias in patients at increased risk for sudden death after acute myocardial infarction: consecutive ambulatory electrocardiographic recordings of 88 patients.

C. Pratt, D. Slymen, A. Hallstrom, 1987, The American journal of cardiology.

Comparison of clinical variables and variables derived from a limited predischarge exercise test as predictors of early and late mortality after myocardial infarction.

D. Waters, P. Théroux, A. Bouchard, 1985, Journal of the American College of Cardiology.

Benefits and Safety of Tirofiban Among Acute Coronary Syndrome Patients With Mild to Moderate Renal Insufficiency: Results From the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Trial

S. Snapinn, P. Théroux, J. Januzzi, 2002, Circulation.

Left ventricular ejection fraction to predict early mortality in patients with non-ST-segment elevation acute coronary syndromes.

P. Théroux, X. Bosch, P. Théroux, 2005, American heart journal.

Optimizing glycoprotein IIb/IIIa receptor antagonist use for the non-ST-segment elevation acute coronary syndromes: risk stratification and therapeutic intervention.

C. Cannon, W. Boden, P. Théroux, 2003, American heart journal.

Thrombosis in coronary artery disease: its pathophysiology and control

P. Théroux, P. Théroux, 2002 .

An integrated clinical approach to predicting the benefit of tirofiban in non-ST elevation acute coronary syndromes. Application of the TIMI Risk Score for UA/NSTEMI in PRISM-PLUS.

E. Antman, E. Braunwald, D. Morrow, 2002, European heart journal.

Platelet glycoprotein IIb/IIIa receptor inhibition in non-ST-elevation acute coronary syndromes: early benefit during medical treatment only, with additional protection during percutaneous coronary intervention.

R. Califf, E. Topol, M. Simoons, 1999, Circulation.

Intracoronary thrombus and platelet glycoprotein IIb/IIIa receptor blockade with tirofiban in unstable angina or non-Q-wave myocardial infarction. Angiographic results from the PRISM-PLUS trial (Platelet receptor inhibition for ischemic syndrome management in patients limited by unstable signs and s

S. Snapinn, P. Théroux, X. Zhao, 1999, Circulation.

Intravenous diltiazem in acute myocardial infarction. Diltiazem as adjunctive therapy to activase (DATA) trial.

P. Théroux, J. Grégoire, M. Juneau, 1998, Journal of the American College of Cardiology.

Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction.

V. Fuster, P. Théroux, P. Théroux, 1998, Circulation.

Unstable angina--report from a Canadian expert roundtable.

P. Armstrong, J. Cairns, P. Théroux, 1996, The Canadian journal of cardiology.

Angiographic features of vein grafts versus ungrafted coronary arteries in patients with unstable angina and previous bypass surgery.

P. Théroux, B. Thibault, P. de Guise, 1996, Journal of the American College of Cardiology.

Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study.

P. Théroux, M. Knudtson, A. Fung, 1996, Circulation.

Aspirin Versus Heparin to Prevent Myocardial Infarction During the Acute Phase of Unstable Angina

D. Waters, P. Théroux, J. Mccans, 1993, Circulation.

Aspirin, heparin, or both to treat acute unstable angina.

P. Théroux, J. Mccans, M. Juneau, 1988, The New England journal of medicine.

Diltiazem and reinfarction in patients with non-Q-wave myocardial infarction. Results of a double-blind, randomized, multicenter trial.

R. Kleiger, M. Gheorghiade, M. B. Perryman, 1986, The New England journal of medicine.

Previously Undiagnosed Variant Angina as a Cause of Chest Pain after Coronary Artery Bypass Surgery

D. Waters, P. Théroux, J. Crittin, 1980, Circulation.

Assessment and management of acute coronary syndromes (ACS): a Canadian perspective on current guideline-recommended treatment--part 1: non-ST-segment elevation ACS.

James M Brophy, Robert C Welsh, J. Brophy, 2011, The Canadian journal of cardiology.

Programmed ventricular stimulation in survivors of an acute myocardial infarction.

D. Waters, M. Bourassa, P. Théroux, 1985, Circulation.

Hemodynamic and therapeutic effects of intravenous dopamine.

M. Bourassa, P. Théroux, H. Mizgala, 1977, Canadian Medical Association journal.

Calcium Antagonists

D. Waters, P. Théroux, Y. Taeymans, 1983, Drugs.

Pexelizumab, an Anti-C5 Complement Antibody, as Adjunctive Therapy to Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction: The COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) Trial

P. Armstrong, W. Weaver, C. Granger, 2003, Circulation.

PATHOPHYSIOLOGY AND NATURAL HISTORY

P. Théroux, J. Latour, C. LEGER-GAUTHIER, 2005 .

High risk patient after recovery from myocardial infarction.

A. Moise, P. Théroux, 1983, Journal of the American College of Cardiology.

Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion.

P. Théroux, M. Galiñanes, D. Garcia-Dorado, 1987, Cardiovascular research.

Coronary arterial reperfusion. III. Early and late effects on regional myocardial function and dimensions in conscious dogs.

J. Ross, S. Sasayama, P. Théroux, 1976, The American journal of cardiology.

Inhibition of the Sodium-Hydrogen Exchanger With Cariporide to Prevent Myocardial Infarction in High-Risk Ischemic Situations: Main Results of the GUARDIAN Trial

H. White, B. Chaitman, J. Schroeder, 2000, Circulation.

Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspirin: The ACUTE II study☆☆☆★

H. White, P. Théroux, S. Borzak, 2002 .

Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction: results from the CARDINAL study.

P. Armstrong, W. Weaver, C. Granger, 2006, European heart journal.

ACC/AHA 2002 guideline update for the management of patients with unstable angina and non–ST-segment elevation myocardial infarction—summary article

J. W. Schaeffer, R. Califf, E. Antman, 2002 .

Predictors of stroke within 30 days in patients with non-ST-segment elevation acute coronary syndromes.

R. Califf, E. Steyerberg, P. Armstrong, 2006, European heart journal.

J. Brophy, E. Rahme, P. Théroux, 2001, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Antithrombotic agents in coronary artery disease.

J. Cairns, P. Théroux, T. Meade, 2001, Chest.

Effects of Antithrombotic Agents on Mortality and Nonfatal Cardiac Events

P. Théroux, R. Lidón, P. Théroux, 1994 .

A pilot, early angiographic patency study using a direct thrombin inhibitor as adjunctive therapy to streptokinase in acute myocardial infarction.

P. Théroux, J. Lespérance, R. Lidón, 1994, Circulation.

Influence of fibrinolysis and percutaneous transluminal coronary angioplasty on the frequency of ventricular premature complexes.

D. Waters, P. Théroux, M. Juneau, 1989, The American journal of cardiology.

Assessment and management of acute coronary syndromes (ACS): a Canadian perspective on current guideline-recommended treatment--part 2: ST-segment elevation myocardial infarction.

J. Brophy, J. Cox, S. Mehta, 2011, The Canadian journal of cardiology.

Coronary heart disease Predictors of stroke within 30 days in patients with non-ST-segment elevation acute coronary syndromes

R. Califf, E. Steyerberg, P. Armstrong, 2006 .

Medical Decision Making in the Choice of a Thrombolytic Agent for Acute Myocardial Infarction

J. Brophy, P. Théroux, L. Joseph, 1999, Medical decision making : an international journal of the Society for Medical Decision Making.

The delay to thrombolysis: an analysis of hospital and patient characteristics. Quebec Acute Coronary Care Working Group.

J. Brophy, P. Théroux, J. Diodati, 1998, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

A new look at coronary angiograms: plaque morphology as a help to diagnosis and to evaluate outcome

D. Waters, P. Théroux, G. Hudon, 1994, The International Journal of Cardiac Imaging.

Late (> 48 hr) myocardial infarction after PTCA: Clinical and angiographic characteristics of infarction related or not to the angioplasty site

P. Théroux, J. Tanguay, J. Lespérance, 2001, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Prognostic significance of elevated creatine kinase MB after coronary bypass surgery and after an acute coronary syndrome: results from the GUARDIAN trial.

B. Chaitman, P. Théroux, N. Danchin, 2003, The Journal of thoracic and cardiovascular surgery.

A score predicts failure of reperfusion after fibrinolytic therapy for acute myocardial infarction.

Wanzhen Gao, James T Stewart, Krishnan Ramanathan, 2003, American heart journal.

Clinical predictors of angina following myocardial infarction.

D. Waters, C. Halphen, H. Mizgala, 1979, The American journal of medicine.

Antiplatelet Therapy in Coronary Disease: What Agent to Use, When, and How?

P. Théroux, P. Théroux, 1998, Journal of Thrombosis and Thrombolysis.

Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty.

S. Nattel, J. Tardif, J. Tardif, 2000, Circulation.

Initial Experience With a Direct Antithrombin, Hirulog, in Unstable Angina Anticoagulant, Antithrombotic, and Clinical Effects

P. Théroux, M. Juneau, J. Maraganore, 1993, Circulation.

Design of a multicenter, double-blind study to assess the effects of prophylactic diltiazem on early reinfarction after non-Q-wave acute myocardial infarction: diltiazem reinfarction study.

M. Gheorghiade, W. Boden, M. Crawford, 1986, The American journal of cardiology.

Hemodynamic effects of calcium ion antagonists after acute myocardial infarction.

D. Waters, M. Bourassa, P. Théroux, 1980, Clinical and investigative medicine. Medecine clinique et experimentale.

Intracoronary infusion of superoxide dismutase and reperfusion injury in the pig heart

F. Fernández‐Avilés, P. Théroux, D. Garcia-Dorado, 1990, Basic Research in Cardiology.

Diltiazem and progression of myocardial ischemic damage during coronary artery occlusion and reperfusion in porcine hearts.

F. Fernández‐Avilés, P. Théroux, M. Galiñanes, 1987, Journal of the American College of Cardiology.

Enhancing thrombolysis with adjunctive therapy

P. Théroux, P. Théroux, 2004, Journal of Thrombosis and Thrombolysis.

Upstream use of tirofiban in patients admitted for an acute coronary syndrome in hospitals with or without facilities for invasive management. PRISM-PLUS Investigators.

P. Théroux, T. Huynh, D. Grandmont, 2001, American Journal of Cardiology.

Effects of long-term, moderate-intensity oral anticoagulation in addition to aspirin in unstable angina

S. Yusuf, M. Keltai, B. Lewis, 2001 .

Effects of long-term, moderate-intensity oral anticoagulation in addition to aspirin in unstable angina. The Organization to Assess Strategies for Ischemic Syndromes (OASIS) Investigators.

S. Yusuf, M. Keltai, J. Varigos, 2001, Journal of the American College of Cardiology.

Selective Inhibition of the Contractile Apparatus: A New Approach to Modification of Infarct Size, Infarct Composition, and Infarct Geometry During Coronary Artery Occlusion and Reperfusion

F. Fernández‐Avilés, P. Théroux, D. Garcia-Dorado, 1992, Circulation.

Technetium-99m sestamibi tomography in patients with spontaneous chest pain: correlations with clinical, electrocardiographic and angiographic findings.

D. Gagnon, P. Théroux, J. Grégoire, 1991, Journal of the American College of Cardiology.

Effects of Thrombolytic Therapy Administered 6 to 24 Hours After Myocardial Infarction on the Signal‐Averaged ECG: Results of a Multicenter Randomized Trial

E. Topol, C. Naylor, P. Armstrong, 1994, Circulation.

Circadian variation in the onset of unstable angina and non-Q-wave acute myocardial infarction (the TIMI III Registry and TIMI IIIB).

E. Braunwald, C. Cannon, P. Stone, 1997, The American journal of cardiology.

Angiographic and clinical progression in unstable angina. From clinical observations to clinical trials.

P. Théroux, P. Théroux, 1995, Circulation.

Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes.

S. Mehta, J. Eikelboom, D. Fitchett, 2011, European heart journal.

Outcomes among non-ST-segment elevation acute coronary syndromes patients with no angiographically obstructive coronary artery disease: observations from 37,101 patients

R. Califf, R. Giugliano, L. Newby, 2014, European heart journal. Acute cardiovascular care.

Upstream Use of Small-Molecule Glycoprotein IIb/IIIa Inhibitors in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes: A Systematic Overview of Randomized Clinical Trials

V. Hasselblad, R. Califf, R. Giugliano, 2011, Circulation. Cardiovascular quality and outcomes.

A risk score system for predicting adverse outcomes and magnitude of benefit with glycoprotein IIb/IIIa inhibitor therapy in patients with unstable angina pectoris.

M. Sabatine, S. Snapinn, J. Januzzi, 2001, The American journal of cardiology.

Fibrinopeptide A and platelet factor levels in unstable angina pectoris.

P. Théroux, J. Latour, C. LEGER-GAUTHIER, 1987, Circulation.

Concerning the mechanism of pexelizumab's benefit in acute myocardial infarction.

P. Armstrong, W. Weaver, C. Granger, 2006, American heart journal.

Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years.

R. Califf, R. Giugliano, L. Newby, 2013, International journal of cardiology.

Clinical and angiographic predictors of new total coronary occlusion in coronary artery disease: analysis of 313 nonoperated patients.

M. Bourassa, P. Théroux, Y. Taeymans, 1984, The American journal of cardiology.

Coping with new challenges in acute coronary syndromes.

P. Théroux, B. Labarthe, P. Théroux, 2006, The Canadian journal of cardiology.

Unstable angina and progression of coronary atherosclerosis.

D. Waters, M. Bourassa, P. Théroux, 1983, The New England journal of medicine.

Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts.

P. Stein, J. Dalen, P. Théroux, 1995, Chest.

Angiographic findings after myocardial infarction in patients with previous bypass surgery: explanations for smaller infarcts in this group compared with control patients.

D. Waters, P. Théroux, P. Crean, 1985, Circulation.

Prognostic significance of progression of coronary artery disease.

P Théroux, M. Bourassa, P. Théroux, 1985, The American journal of cardiology.

Clinical manifestations and pathophysiology of myocardial ischemia with special reference to coronary artery spasm and the role of slow channel calcium blockers.

D. Waters, P. Théroux, J. Latour, 1982, Progress in cardiovascular diseases.

Myocardial Ischemia and Infarction lopidogrel Inhibits Platelet-Leukocyte nteractions and Thrombin Receptor gonist Peptide-Induced Platelet Activation n Patients With an Acute Coronary Syndrome

P. Théroux, ihui Xiao, P. Théroux, 2016 .

Comparison of Primary Percutaneous Coronary Intervention and Fibrinolytic Therapy in ST-Segment–Elevation Myocardial Infarction: Bayesian Hierarchical Meta-Analyses of Randomized Controlled Trials and Observational Studies

J. Tu, M. Labrecque, J. O'Loughlin, 2009, Circulation.

Geometric features of coronary artery lesions favoring acute occlusion and myocardial infarction: a quantitative angiographic study.

P Théroux, P Ducimetière, P. Ducimetiere, 1999, Journal of the American College of Cardiology.

Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes.

P. Théroux, P. Tornos, D. Garcia-Dorado, 1995, Circulation.

Are qualitative features of coronary artery lesions useful in predicting progression

D. Waters, P. Théroux, G. Hudon, 1994 .

Demographics, treatment and outcome of acute coronary syndromes: 17 years of experience in a specialized cardiac centre.

P. Théroux, J. Tanguay, J. Grégoire, 2006, The Canadian journal of cardiology.

Spontaneous regression of coronary artery obstructions: incidence in 313 consecutive repeat angiograms.

M. Bourassa, P. Théroux, J. Lespérance, 1985, Catheterization and cardiovascular diagnosis.

Clinical and Angiographic Factors Associated With Coronary Artery Disease Progression of Coronary Artery Disease

Yves Taeymans, D. Waters, P. Finès, 1984 .

Regional Myocardial Function and Dimensions Early and Late after Myocardial Infarction in the Unanesthetized Dog

D Franklin, C M Bloor, J W Covell, 1977, Circulation research.

Factors influencing the long-term prognosis of treated patients with variant angina.

D. Waters, D. Miller, P. Théroux, 1983, Circulation.

Predictive value and safety of low level exercise tolerance testing early after acute myocardial infarction

D. Waters, C. Halphen, H. Mizgala, 1978 .

Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: results from the PREPAIR randomized study.

J. Tardif, C. Berry, P. Théroux, 2008, Journal of the American College of Cardiology.

PATHOPHYSIOLOGY AND NATURAL HISTORY

D. Waters, P. Théroux, X. Bosch, 2005 .

Job strain and risk of acute recurrent coronary heart disease events.

G. Dagenais, C. Brisson, P. Théroux, 2007, JAMA.

931-111 Platelet Activation and Aggregation by Therapeutic Doses of Heparin

Zihui Xiao, J. Plachetka, P. Théroux, 1995 .

The Past, the Present, the Future

P. Théroux, Pierre Théroux, P. Théroux, 2011 .

Evaluation of prognosis I year after myocardial infarction

M. Bourassa, A. Moise, P. Théroux, 1984 .

Antithrombotic properties of transdermal nitroglycerin in stable angina pectoris.

P. Théroux, L. Lacoste, R. Lidón, 1994, The American journal of cardiology.

Influence of baseline lipids on effectiveness of pravastatin in the CARE Trial. Cholesterol And Recurrent Events.

M. Pfeffer, J. Rouleau, E. Braunwald, 1999, Journal of the American College of Cardiology.

Genetic predictors of depressive symptoms in cardiac patients

M. Dubé, Q. Duan, G. Rouleau, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Design features of a controlled clinical trial to assess the effect of a calcium entry blocker upon the progression of coronary artery disease.

D. Waters, P. Théroux, G. Gosselin, 1987, Controlled clinical trials.

Effect of micronized fenofibrate on plasma lipoprotein levels and hemostatic parameters of hypertriglyceridemic patients with low levels of high-density lipoprotein cholesterol in the fed and fasted state.

N. H. Nguyen, P. Théroux, J. Genest, 2000, Journal of cardiovascular pharmacology.

Temporal changes in biomarkers and their relationships to reperfusion and to clinical outcomes among patients with ST segment elevation myocardial infarction

P. Armstrong, C. Granger, K. Mahaffey, 2016, Journal of Thrombosis and Thrombolysis.

Hemodynamic effects of a single oral dose of nifedipine following acute myocardial infarction.

D. Waters, H. Mizgala, P. Théroux, 1980, Chest.

Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.

A. Parkhomenko, M. Sabatine, A. Budaj, 2016, JAMA.

Effects of Diltiazem on Experimental Myocardial Ischemia and on Left Ventricular Performance

M. Bourassa, P. Théroux, J. Clozel, 1983, Circulation research.

Prevalence and non-invasive predictors of left main or three-vessel coronary disease: evidence from a collaborative international meta-analysis including 22 740 patients

M. Budoff, R. Rubinshtein, F. Gaita, 2012, Heart.

Increased mortality after coronary artery bypass graft surgery is associated with increased levels of postoperative creatine kinase-myocardial band isoenzyme release: results from the GUARDIAN trial.

B. Chaitman, A. Jessel, B. Keller, 2001, Journal of the American College of Cardiology.

Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study.

B. Chaitman, R. Bolli, P. Théroux, 2003, The Journal of thoracic and cardiovascular surgery.

Long-term reproducibility and significance of provokable ventricular arrhythmias after myocardial infarction.

D. Waters, M. Bourassa, P. Théroux, 1986, Journal of the American College of Cardiology.

Platelet Glycoprotein IIb/IIIa Inhibitors Reduce Mortality in Diabetic Patients With Non–ST-Segment-Elevation Acute Coronary Syndromes

Deepak L. Bhatt, R. Califf, E. Topol, 2001, Circulation.

Complement activity and pharmacological inhibition in cardiovascular disease.

P. Théroux, C. Martel, P. Théroux, 2006, The Canadian journal of cardiology.

The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes.

M. Irwin, N. Frasure-smith, F. Lespérance, 2004, The American journal of psychiatry.

Aspirin, Warfarin, or the Combination for Secondary Prevention of Coronary Events in Patients With Acute Coronary Syndromes and Prior Coronary Artery Bypass Surgery

S. Solymoss, P. Théroux, T. Huynh, 2001, Circulation.

Improved gas chromatographic determination of diltiazem and deacetyldiltiazem in human plasma.

P. Biron, Y. Taeymans, J. Clozel, 1984, Journal of Pharmacy and Science.

Non-invasive pulsed Doppler study of mitral stenosis and mitral regurgitation: preliminary study.

D. Waters, M. Bourassa, B. Diebold, 1979, British heart journal.

Favorable effects of orally administered digoxin on left heart size and ventricular wall motion in patients with previous myocardial infarction.

J. Ross, R. O'rourke, M. Crawford, 1976, The American journal of cardiology.

A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians.

G. Rouleau, G. Turecki, P. Théroux, 2001, American heart journal.

Prognostic significance of newly acquired bundle branch block after aortic valve replacement.

P. Théroux, M. Talajic, M. Dubuc, 2004, The American journal of cardiology.

Circadian variation in variant angina.

D. Waters, D. Miller, P. Théroux, 1984, The American journal of cardiology.

DEPRESSION AND 1-YEAR PROGNOSIS IN UNSTABLE ANGINA

N. Frasure-smith, F. Lespérance, P. Théroux, 1998 .

Is progression of coronary artery disease occurring at bouts or as a continuous process? Serial cineangiographic studies in 44 patients.

D. Waters, P. Théroux, J. Lespérance, 1984, Computers and biomedical research, an international journal.

Low-Dose Combined Therapy with Fluvastatin and Cholestyramine in Hyperlipidemic Patients

P. Théroux, D. Sprecher, J. Abrams, 1994, Annals of Internal Medicine.

Endothelial Progenitor Cells Bind and Inhibit Platelet Function and Thrombus Formation

M. Tabrizian, P. Théroux, M. Sirois, 2009, Circulation.

Effects ofThrombolytic Therapy Administered 6to24HoursAfterMyocardial Infarction on theSignal-Averaged ECG Results ofa Multicenter Randomized Trial

P. Théroux, 1994 .

Depression, C-reactive Protein and Two-year Major Adverse Cardiac Events in Men after Acute Coronary Syndromes

M. Irwin, N. Frasure-smith, F. Lespérance, 2007, Biological Psychiatry.

Pulsed Doppler Echocardiographic Study of Mitral Stenosis

D. Waters, M. Bourassa, P. Peronneau, 1980, Circulation.

Noninvasive assessment of aortocoronary bypass graft patency using pulsed Doppler echocardiography.

P Peronneau, M. Bourassa, B. Diebold, 1979, The American journal of cardiology.

Cost-effectiveness of enoxaparin compared with unfractionated heparin in ST elevation myocardial infarction patients undergoing pharmacological reperfusion: a Canadian analysis of the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment - Thrombolysis in Myocardial Infar

R. Welsh, P. Kolm, Zugui Zhang, 2009, The Canadian journal of cardiology.

Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups

J. Ioannidis, R. Califf, E. Steyerberg, 2006, Heart.

Myocardial cell protection : a challenging time for action and a challenging time for clinical research.

P. Théroux, P. Théroux, 2000, Circulation.

Efficacy and Safety of Vorapaxar as Approved for Clinical Use in the United States

Marc P. Bonaca, David A. Morrow, Benjamin M. Scirica, 2015, Journal of the American Heart Association.

H. White, P. Théroux, S. Borzak, 2002, American heart journal.

Achieving LDL cholesterol, non-HDL cholesterol, and apolipoprotein B target levels in high-risk patients: Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapY (MERCURY) II.

C. Ballantyne, E. Stein, P. Théroux, 2006, American heart journal.

Myocardial infarction in patients with previous coronary artery bypass surgery.

D. Waters, P. Théroux, L. Campeau, 1984, Journal of the American College of Cardiology.

Factors associated with progression of coronary artery disease in patients with normal or minimally narrowed coronary arteries.

D. Waters, P. Théroux, Y. Taeymans, 1985, The American journal of cardiology.

Revisiting the Canadian Cardiovascular Society grading of stable angina pectoris after a quarter of a century of use.

G. Dagenais, C. Naylor, P. Armstrong, 2002, The Canadian journal of cardiology.

The ergonovine test--to catch a leprechaun.

D. Waters, P. Théroux, P. Théroux, 1983, International journal of cardiology.

Comparative Sensitivity ofExercise, ColdPressor andErgonovine Testing inProvoking Attacks ofVariant AnginainPatients withActive Disease

P. Théroux, J. Szlachcic, P. Théroux, 1983 .

A comparative study of calcium-ion antagonists in patients with variant angina.

D. Waters, J. Szlachcic, H. Mizgala, 1980, Clinical and investigative medicine. Medecine clinique et experimentale.

Prevention of progression of minimal coronary lesions with a calcium channel blocker

D. Waters, R. Havel, M. Reitman, 1990 .

The pre-hospital fibrinolysis experience in Europe and North America and implications for wider dissemination.

J. Tu, M. Schull, A. Denktas, 2011, JACC. Cardiovascular interventions.

Influence of tachycardia and arterial hypertension on infarct size in the pig.

D. Garcia-Dorado, J. Alonso, J. Elízaga, 1988, Cardiovascular Research.