Megha Subramanian

发表

Poly(ADP-ribose) glycohydrolase inhibition sequesters NAD+ to potentiate the metabolic lethality of alkylating chemotherapy in IDH mutant tumor cells.

H. Wakimoto, D. Cahill, Julie J. Miller, 2020, Cancer discovery.

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases

A. Giobbie-Hurder, S. Carter, H. Wakimoto, 2019, Clinical Cancer Research.

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

Brian L. Shaw, A. Giobbie-Hurder, S. Carter, 2020, Nature Medicine.

Targeting the PI3K/Akt/mTOR-pathway with the pan-Akt inhibitor GDC-0068 in PIK3CA-mutant breast cancer brain metastases.

A. Giobbie-Hurder, S. Carter, H. Wakimoto, 2019, Neuro-oncology.

RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes

J. McIninch, Elena K. Stamenova, Svetlana Shulga-Morskaya, 2022, bioRxiv.

Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations

Brian L. Shaw, D. Cahill, P. Brastianos, 2019, Cancer.

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

McKenzie L. Shaw, Brian L. Shaw, S. Carter, 2021, bioRxiv.

Sirtuin activation targets IDH-mutant tumors.

H. Wakimoto, D. Cahill, Julie J. Miller, 2020, Neuro-oncology.

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Brian L. Shaw, S. Carter, S. Prakadan, 2021, Nature Communications.

Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid

Brian L. Shaw, A. Giobbie-Hurder, S. Carter, 2021, JAMA network open.

Author Correction: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Brian L. Shaw, S. Carter, S. Prakadan, 2021, Nature Communications.

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

Brian L. Shaw, A. Giobbie-Hurder, R. Sullivan, 2020, Nature Network Boston.

Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition.

McKenzie L. Shaw, Brian L. Shaw, S. Carter, 2022, Cancer immunology research.

Publisher Correction: Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

Brian L. Shaw, A. Giobbie-Hurder, S. Carter, 2020, Nature Medicine.

Robust and durable prophylactic protection conferred by RNA interference in preclinical models of SARS-CoV-2

Svetlana Shulga Morskaya, J. McIninch, R. Spreafico, 2022, bioRxiv.