S. E. Kassab

发表

Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma

N. Omar, S. El-Naggar, Samar Mowafy, 2019, Journal of enzyme inhibition and medicinal chemistry.

Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme

A. A. Abdel Moneim, S. A. El‐Hawash, M. El-Miligy, 2022, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of New 9-glycosyl-4,9-dihydropyrano [3,4-b]indole-1(3H)-ones as Antibacterial Agents

Kamelia M. Amin, S. E. Kassab, N. M. Eid, 2011, Nucleosides, nucleotides & nucleic acids.

Rational Design and Synthesis of New Selective COX-2 Inhibitors with In Vivo PGE2-Lowering Activity by Tethering Benzenesulfonamide and 1,2,3-Triazole Pharmacophores to Some NSAIDs

A. A. Abdel Moneim, H. Daabees, S. A. El‐Hawash, 2022, Pharmaceuticals.

A promising anti-cancer and anti-oxidant agents based on the pyrrole and fused pyrrole: synthesis, docking studies and biological evaluation.

S. S. Fatahala, E. Shalaby, S. E. Kassab, 2015, Anti-cancer agents in medicinal chemistry.

Base-catalyzed one-step synthesis of 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

Xinhua He, F. Xue, Geoffrey A. Heinzl, 2015 .

Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors.

H. Daabees, S. E. Kassab, Haydi S. Elbordiny, 2018, European journal of medicinal chemistry.

Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents.

N. Farag, K. Abouzid, R. Serya, 2014, Bioorganic chemistry.

Synthesis of 1H-Indole-2,3-Dione-3-Thiosemicarbazone Ribonucleosides as Antibacterial Agents

S. E. Kassab, N. M. Eid, G. H. Hegazy, 2010, Nucleosides, nucleotides & nucleic acids.

Synthesis of novel d-α-galactopyranosyl-l-seryl/l-threonyl-l-alanyl-l-alanine as useful precursors of new glycopeptide antibiotics with computational calculations studies.

A. Khodair, Asmaa M. Fahim, N. A. Kheder, 2022, Carbohydrate research.

Structural Basis of Selective Human Indoleamine‐2,3‐dioxygenase 1 (hIDO1) Inhibition

Samar Mowafy, S. E. Kassab, 2021, ChemMedChem.

Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity.

K. Abouzid, Mohamed Elagawany, E. Awad, 2021, Bioorganic chemistry.

Indomethacin from Anti-Inflammatory to Anticancer Agent

S. E. Kassab, 2018, Medicinal Chemistry.

Design, synthesis and biological evaluation of novel thiohydantoin derivatives as antiproliferative agents: A combined experimental and theoretical assessments

A. Khodair, Khaled R. A. Abdellatif, M. Awad, 2022, Journal of Molecular Structure.

Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies.

A. A. Abdel Moneim, H. Daabees, AyaHamdino Rashad, 2021, Bioorganic chemistry.

Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities.

Hamed I. Ali, M. Khedr, M. Abdalla, 2017, European journal of medicinal chemistry.