Shaorui Chen

发表

Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion

J. Issa, J. Jelinek, G. Laumet, 2018, The Journal of Neuroscience.

Increased Spinal Cord Na+-K+-2Cl− Cotransporter-1 (NKCC1) Activity Contributes to Impairment of Synaptic Inhibition in Paclitaxel-induced Neuropathic Pain*

G. Laumet, H. Pan, Hong Chen, 2014, The Journal of Biological Chemistry.

Sustained Inhibition of Neurotransmitter Release from Nontransient Receptor Potential Vanilloid Type 1-Expressing Primary Afferents by μ-Opioid Receptor Activation-Enkephalin in the Spinal Cord

H. Pan, Hong-yi Zhou, Hong Chen, 2008, Journal of Pharmacology and Experimental Therapeutics.

Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain

Guang-fen Zhang, H. Pan, Hong Chen, 2022, The Journal of biological chemistry.

Calcineurin Inhibition Causes α2δ-1–Mediated Tonic Activation of Synaptic NMDA Receptors and Pain Hypersensitivity

H. Pan, Hong Chen, Shaorui Chen, 2020, The Journal of Neuroscience.

Stereospecific Effect of Pregabalin on Ectopic Afferent Discharges and Neuropathic Pain Induced by Sciatic Nerve Ligation in Rats

H. Pan, Shaorui Chen, Zemin Xu, 2001, Anesthesiology.

Gene therapy approaches to restore chloride homeostasis for treating neuropathic pain

H. Pan, Saiyun Hou, Shaorui Chen, 2020 .

CK 2 Regulates NMDA Receptor Activity in Spinal Cords and Pain Hypersensitivity Induced by Nerve Injury

H. Byun, H. Pan, Hong-yi Zhou, 2014 .

Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats

A. Sood, G. Lopez-Berestein, H. Han, 2009, Journal of neurochemistry.

Control of Glycinergic Input to Spinal Dorsal Horn Neurons by Distinct Muscarinic Receptor Subtypes Revealed Using Knockout Mice

J. Wess, D. Gautam, H. Pan, 2007, Journal of Pharmacology and Experimental Therapeutics.

Opposing Functions of Spinal M2, M3, and M4 Receptor Subtypes in Regulation of GABAergic Inputs to Dorsal Horn Neurons Revealed by Muscarinic Receptor Knockout Mice

J. Wess, M. Matsui, D. Gautam, 2006, Molecular Pharmacology.

M2, M3, and M4 Receptor Subtypes Contribute to Muscarinic Potentiation of GABAergic Inputs to Spinal Dorsal Horn Neurons

De-Pei Li, H. Pan, Hong-Mei Zhang, 2005, Journal of Pharmacology and Experimental Therapeutics.

Functional Activity of the M2 and M4 Receptor Subtypes in the Spinal Cord Studied with Muscarinic Acetylcholine Receptor Knockout Mice

J. Wess, H. Pan, Shaorui Chen, 2005, Journal of Pharmacology and Experimental Therapeutics.

Functional Activity of the M 2 and M 4 Receptor Subtypes in the Spinal Cord Studied with Muscarinic Acetylcholine Receptor Knockout Mice

J. Wess, H. Pan, Shaorui Chen, 2005 .

M 2 , M 3 and M 4 Receptor Subtypes Contribute to Muscarinic Potentiation of GABAergic Inputs to Spinal Dorsal Horn Neurons

De-Pei Li, H. Pan, Hong-Mei Zhang, 2004 .

Potentiates Opioid Analgesia Opioid Receptors But Paradoxically μ Spinal of TRPV1-Expressing Sensory Neurons Reduces

H. Pan, Haibin Wang, S. Kong, 2015 .

Loss of TRPV1-expressing sensory neurons reduces spinal mu opioid receptors but paradoxically potentiates opioid analgesia.

H. Pan, Shaorui Chen, 2006, Journal of neurophysiology.

A-Type Voltage-Gated K + Currents Influence Firing Properties of Isolectin B 4-Positive but Not-Negative Primary Sensory Neurons

H. Pan, A. Vydyanathan, Shaorui Chen, 2005 .

Differential Sensitivity of N- and P/Q-Type Ca2+ Channel Currents to a μ Opioid in Isolectin B -Positive and -Negative Dorsal Root Ganglion Neurons

H. Pan, Shaorui Chen, Zi-Zhen Wu, 2004, Journal of Pharmacology and Experimental Therapeutics.

Differential Sensitivity of N- and P/Q-Type Ca 2 (cid:1) Channel Currents to a (cid:1) Opioid in Isolectin B 4 -Positive and -Negative Dorsal Root Ganglion Neurons

H. Pan, Shaorui Chen, Zi-Zhen Wu, 2004 .

Cardiac Sympathetic Afferents in Cats Myocardial Ischemia Recruits Mechanically Insensitive

P. Reeh, H. Pan, R. Foreman, 2015 .

Myocardial ischemia recruits mechanically insensitive cardiac sympathetic afferents in cats.

H. Pan, Shaorui Chen, 2002, Journal of neurophysiology.

Role of protons in activation of cardiac sympathetic C‐fibre afferents during ischaemia in cats

J. Longhurst, J. Eisenach, H. Pan, 1999, The Journal of physiology.

Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow

H. Pan, Shaorui Chen, Jing-Jing Zhou, 2022, Circulation research.

Effect of systemic and intrathecal gabapentin on allodynia in a new rat model of postherpetic neuralgia

H. Pan, Shaorui Chen, 2005, Brain Research.

μ-Opioid receptors in primary sensory neurons are involved in supraspinal opioid analgesia

H. Pan, Shaorui Chen, Jie Sun, 2019, Brain Research.

Calcineurin inhibitor induces pain hypersensitivity by potentiating pre‐ and postsynaptic NMDA receptor activity in spinal cords

Hong Chen, H. Pan, Yi-Min Hu, 2014, The Journal of physiology.

Microsoft Word-64192700-file00

H. Byun, H. Pan, Hong-yi Zhou, 2013 .

Potentiation of spinal α2-adrenoceptor analgesia in rats deficient in TRPV1-expressing afferent neurons

T. Richardson, H. Pan, H. Pan, 2007, Neuropharmacology.

Inhibition of β-ARK1 Ameliorates Morphine-induced Tolerance and Hyperalgesia Via Modulating the Activity of Spinal NMDA Receptors

Hong Chen, H. Pan, Yilin Zhao, 2018, Molecular Neurobiology.

μ‐Opioid receptors in primary sensory neurons are essential for opioid analgesic effect on acute and inflammatory pain and opioid‐induced hyperalgesia

H. Pan, Hong Chen, Shaorui Chen, 2019, The Journal of physiology.

Focal Cerebral Ischemia and Reperfusion Induce Brain Injury Through &agr;2&dgr;-1–Bound NMDA Receptors

H. Pan, Lingyong Li, Hui-jie Ma, 2018, Stroke.

The (cid:2) 2 (cid:3) -1–NMDA receptor coupling is essential for corticostriatal long-term potentiation and is involved in learning and memory

De-Pei Li, H. Pan, Shaorui Chen, 2018 .

Dynamic Control of Glutamatergic Synaptic Input in the Spinal Cord by Muscarinic Receptor Subtypes Defined Using Knockout Mice*

J. Wess, H. Pan, W. Yuan, 2010, The Journal of Biological Chemistry.

Modulation of pain transmission by G-protein-coupled receptors.

De-Pei Li, H. Pan, Hong-Mei Zhang, 2008, Pharmacology & therapeutics.

Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death

E. Yeh, J. Noebels, Yitao Qi, 2014, Neuron.

Nitric oxide stimulates glutamatergic synaptic inputs to baroreceptor neurons through potentiation of Cav2.2-mediated Ca2+ currents

De-Pei Li, Shaorui Chen, 2014, Neuroscience Letters.

Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors

W. Hittelman, De-Pei Li, H. Pan, 2009, Journal of Pharmacology and Experimental Therapeutics.

Altered synaptic input and GABAB receptor function in spinal superficial dorsal horn neurons in rats with diabetic neuropathy

H. Pan, Hong-Mei Zhang, Shaorui Chen, 2007, The Journal of physiology.

Intrathecal Adenosine following Spinal Nerve Ligation in Rat: Short Residence Time in Cerebrospinal Fluid and No Change in A1 Receptor Binding

S. Childers, C. Bantel, J. R. Tobin, 2002, Anesthesiology.

Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury

H. Pan, Xiao-gao Jin, Shaorui Chen, 2017, Neuropharmacology.

Spinal GABAB receptors mediate antinociceptive actions of cholinergic agents in normal and diabetic rats

H. Pan, Shaorui Chen, 2003, Brain Research.

Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord

H. Pan, Hong Chen, Shaorui Chen, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Associated With Diabetic Neuropathic Pain in Rats Hypersensitivity of Spinothalamic Tract Neurons

L. Garcia-Segura, D. Caruso, M. Milanese, 2015 .

Diabetic neuropathy enhances voltage‐activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons

H. Byun, H. Pan, Xue-hong Cao, 2011, Journal of neurochemistry.

Increased Presynaptic and Postsynaptic α2-Adrenoceptor Activity in the Spinal Dorsal Horn in Painful Diabetic Neuropathy

H. Pan, W. Yuan, Hong Chen, 2011, Journal of Pharmacology and Experimental Therapeutics.

Reduction in voltage‐gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain‐derived neurotrophic factor

H. Byun, H. Pan, Xue-hong Cao, 2010, Journal of neurochemistry.

Regulation of increased glutamatergic input to spinal dorsal horn neurons by mGluR5 in diabetic neuropathic pain

H. Pan, Hong Chen, Shaorui Chen, 2010, Journal of neurochemistry.

Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain

H. Pan, G. Samoriski, Shaorui Chen, 2009, Neuropharmacology.

Up-Regulation of Spinal Muscarinic Receptors and Increased Antinociceptive Effect of Intrathecal Muscarine in Diabetic Rats

H. Pan, Shao‐Rui Chen, Shaorui Chen, 2003, Journal of Pharmacology and Experimental Therapeutics.

Role of Spinal Nitric Oxide in the Inhibitory Effect of [d-Pen2,d-Pen5]-Enkephalin on Ascending Dorsal Horn Neurons in Normal and Diabetic Rats

De-Pei Li, H. Pan, G. Khan, 2002, Journal of Pharmacology and Experimental Therapeutics.

Functional &mgr; Opioid Receptors Are Reduced in the Spinal Cord Dorsal Horn of Diabetic Rats

J. Lakoski, H. Pan, Shaorui Chen, 2002, Anesthesiology.

Hypersensitivity of spinothalamic tract neurons associated with diabetic neuropathic pain in rats.

H. Pan, Shaorui Chen, 2002, Journal of neurophysiology.

Effect of Morphine on Deep Dorsal Horn Projection Neurons Depends on Spinal GABAergic and Glycinergic Tone: Implications for Reduced Opioid Effect in Neuropathic Pain

H. Pan, Shao‐Rui Chen, Yan-Ping Chen, 2005, Journal of Pharmacology and Experimental Therapeutics.

Blocking μ opioid receptors in the spinal cord prevents the analgesic action by subsequent systemic opioids

H. Pan, Shaorui Chen, 2006, Brain Research.

Muscarinic receptor subtypes differentially control synaptic input and excitability of cerebellum‐projecting medial vestibular nucleus neurons

H. Pan, Shaorui Chen, Yun Zhu, 2016, Journal of neurochemistry.

Muscarinic receptor subtypes differentially control synaptic input and excitability of cerebellum‐projecting medial vestibular nucleus neurons

H. Pan, Shaorui Chen, Yun Zhu, 2016, Journal of Neurochemistry.

Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

Fei Yang, Y. Guan, Yan Xu, 2012, The Journal of experimental medicine.

The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

David M. Maclean, V. Jayaraman, H. Pan, 2022, Cell reports.

Spinal Endogenous Acetylcholine Contributes to the Analgesic Effect of Systemic Morphine in Rats

H. Pan, Shaorui Chen, 2001, Anesthesiology.

A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons.

H. Pan, A. Vydyanathan, Shaorui Chen, 2005, Journal of neurophysiology.

Targeting N-methyl-D-aspartate receptors for treatment of neuropathic pain

H. Pan, Hong-yi Zhou, Shaorui Chen, 2011, Expert review of clinical pharmacology.

Systemic Morphine Inhibits Dorsal Horn Projection Neurons through Spinal Cholinergic System Independent of Descending Pathways

H. Pan, Yan-Ping Chen, Shaorui Chen, 2005, Journal of Pharmacology and Experimental Therapeutics.

Nerve Injury Diminishes Opioid Analgesia through Lysine Methyltransferase-mediated Transcriptional Repression of μ-Opioid Receptors in Primary Sensory Neurons*

G. Laumet, H. Pan, Hong Chen, 2016, The Journal of Biological Chemistry.

Role of Spinal NO in Antiallodynic Effect of Intrathecal Clonidine in Neuropathic Rats

J. Eisenach, H. Pan, S. R. Chen, 1998, Anesthesiology.

Spinal Nitric Oxide Contributes to the Analgesic Effect of Intrathecal [D-Pen2,D-Pen5]-Enkephalin in Normal and Diabetic Rats

H. Pan, Shaorui Chen, 2003, Anesthesiology.

Removing TRPV1-expressing primary afferent neurons potentiates the spinal analgesic effect of δ-opioid agonists on mechano-nociception

H. Pan, Shaorui Chen, 2008, Neuropharmacology.

RE1-silencing transcription factor controls the acute-to-chronic neuropathic pain transition and Chrm2 receptor gene expression in primary sensory neurons

H. Pan, Hong Chen, Shaorui Chen, 2018, The Journal of Biological Chemistry.

Casein Kinase II Inhibition Reverses Pain Hypersensitivity and Potentiated Spinal N-Methyl-d-aspartate Receptor Activity Caused by Calcineurin Inhibitor

H. Pan, Yi-Min Hu, Hong Chen, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Role of Presynaptic Muscarinic and GABAB Receptors in Spinal Glutamate Release and Cholinergic Analgesia in Rats

A. Levey, De-Pei Li, H. Pan, 2002, The Journal of physiology.

Antiallodynic Effect of Intrathecal Neostigmine Is Mediated by Spinal Nitric Oxide in a Rat Model of Diabetic Neuropathic Pain

H. Pan, G. Khan, S. R. Chen, 2001, Anesthesiology.

Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain

J. Eisenach, H. Pan, Shaorui Chen, 2000, Brain Research.

Synergistic Effect between Intrathecal Non-NMDA Antagonist and Gabapentin on Allodynia Induced by Spinal Nerve Ligation in Rats

J. Eisenach, H. Pan, Shaorui Chen, 2000, Anesthesiology.

Endogenous AT1 receptor–protein kinase C activity in the hypothalamus augments glutamatergic input and sympathetic outflow in hypertension

H. Pan, Hui-jie Ma, Hong Chen, 2019, The Journal of physiology.

α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly

V. Jayaraman, De-Pei Li, H. Pan, 2021, Cell reports.

Sensing Tissue Ischemia: Another New Function for Capsaicin Receptors?

H. Pan, Shaorui Chen, 2004, Circulation.

Pannexin-1 Up-regulation in the Dorsal Root Ganglion Contributes to Neuropathic Pain Development*

W. Hittelman, G. Laumet, H. Pan, 2015, The Journal of Biological Chemistry.

Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats

R. James, A. Sandner-Kiesling, J. Eisenach, 2002, Pain.

Presynaptic N-Methyl-d-aspartate (NMDA) Receptor Activity Is Increased Through Protein Kinase C in Paclitaxel-induced Neuropathic Pain.

H. Pan, W. Zeng, Hong Chen, 2016, The Journal of biological chemistry.

Effect of 2-(phosphono-methyl)-pentanedioic acid on allodynia and afferent ectopic discharges in a rat model of neuropathic pain.

H. Pan, B. Slusher, K. Wozniak, 2002, The Journal of pharmacology and experimental therapeutics.

α2δ‐1 protein promotes synaptic expression of Ca2+ permeable–AMPA receptors by inhibiting GluA1/GluA2 heteromeric assembly in the hypothalamus in hypertension

Hong Chen, H. Pan, Shaorui Chen, 2022, Journal of neurochemistry.

Microsoft Word-58212310-file00

W. Hittelman, De-Pei Li, Shaorui Chen, 2009 .

Cardiac vanilloid receptor 1‐expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats

De-Pei Li, H. Pan, M. Zahner, 2003, The Journal of physiology.

α2δ‐1 couples to NMDA receptors in the hypothalamus to sustain sympathetic vasomotor activity in hypertension

De-Pei Li, H. Pan, Hui-jie Ma, 2018, The Journal of physiology.

α2δ-1 Is Essential for Sympathetic Output and NMDA Receptor Activity Potentiated by Angiotensin II in the Hypothalamus

De-Pei Li, H. Pan, Lingyong Li, 2018, The Journal of Neuroscience.

α2δ‐1 protein drives opioid‐induced conditioned reward and synaptic NMDA receptor hyperactivity in the nucleus accumbens

Hong Chen, H. Pan, Daozhong Jin, 2022, Journal of neurochemistry.

&agr;2&dgr;-1–Bound N-Methyl-D-aspartate Receptors Mediate Morphine-induced Hyperalgesia and Analgesic Tolerance by Potentiating Glutamatergic Input in Rodents

H. Pan, Hong Chen, Shaorui Chen, 2019, Anesthesiology.

The α2δ-1–NMDA receptor coupling is essential for corticostriatal long-term potentiation and is involved in learning and memory

De-Pei Li, H. Pan, Shaorui Chen, 2018, The Journal of Biological Chemistry.

Angiotensin II Stimulates Spinally Projecting Paraventricular Neurons through Presynaptic Disinhibition

De-Pei Li, H. Pan, Shaorui Chen, 2003, The Journal of Neuroscience.

Nitric oxide inhibits spinally projecting paraventricular neurons through potentiation of presynaptic GABA release.

De-Pei Li, H. Pan, Shaorui Chen, 2002, Journal of neurophysiology.

Group III metabotropic glutamate receptors regulate hypothalamic presympathetic neurons through opposing presynaptic and postsynaptic actions in hypertension.

De-Pei Li, H. Pan, Shaorui Chen, 2020 .

Presynaptic NMDA receptors control nociceptive transmission at the spinal cord level in neuropathic pain

H. Pan, Shaorui Chen, M. Deng, 2019, Cellular and Molecular Life Sciences.

Aminopyridines Potentiate Synaptic and Neuromuscular Transmission by Targeting the Voltage-activated Calcium Channel β Subunit*♦

De-Pei Li, H. Pan, Shaorui Chen, 2009, The Journal of Biological Chemistry.

Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors.

De-Pei Li, H. Pan, De-Pei Li, 2005, Journal of neurophysiology.

Increased α2δ‐1–NMDA receptor coupling potentiates glutamatergic input to spinal dorsal horn neurons in chemotherapy‐induced neuropathic pain

H. Pan, Hong Chen, Shaorui Chen, 2018, Journal of neurochemistry.

Nerve injury increases brain‐derived neurotrophic factor levels to suppress BK channel activity in primary sensory neurons

H. Pan, Shao‐Rui Chen, Xue-hong Cao, 2012, Journal of neurochemistry.

Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes.

H. Pan, Hong-Mei Zhang, Shaorui Chen, 2007, Journal of neurophysiology.

Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats

De-Pei Li, H. Pan, Hong-Mei Zhang, 2006, The Journal of physiology.

Endogenous transient receptor potential ankyrin 1 and vanilloid 1 activity potentiates glutamatergic input to spinal lamina I neurons in inflammatory pain

H. Pan, Hong Chen, Shaorui Chen, 2019, Journal of neurochemistry.

Activation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs.

De-Pei Li, H. Pan, Yu-zhen Pan, 2002, Journal of neurophysiology.

Upregulation of Nuclear Factor of Activated T-Cells by Nerve Injury Contributes to Development of Neuropathic Pain

H. Pan, Shaorui Chen, You‐Qing Cai, 2013, The Journal of Pharmacology and Experimental Therapeutics.

G9a Is Essential for Epigenetic Silencing of K+ Channel Genes in Acute-to-Chronic Pain Transition

J. Issa, J. Jelinek, M. Cesaroni, 2015, Nature Neuroscience.

Chronic opioid potentiates presynaptic but impairs postsynaptic N-methyl-D-aspartic acid receptor activity in spinal cords: implications for opioid hyperalgesia and tolerance.

H. Pan, Hong Chen, Shaorui Chen, 2012, The Journal of biological chemistry.

Nerve Injury Increases GluA2-Lacking AMPA Receptor Prevalence in Spinal Cords: Functional Significance and Signaling Mechanisms

H. Byun, H. Pan, Hong-yi Zhou, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Bortezomib induces neuropathic pain through protein kinase C-mediated activation of presynaptic NMDA receptors in the spinal cord

Hong Chen, H. Pan, Shaorui Chen, 2017, Neuropharmacology.

Regulation of nociceptive transduction and transmission by nitric oxide.

H. Pan, Shaorui Chen, A. Bavencoffe, 2014, Vitamins and hormones.

Nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons.

H. Pan, Xue-hong Cao, Li Li, 2011, The Journal of biological chemistry.

The glutamatergic nature of TRPV1‐expressing neurons in the spinal dorsal horn

H. Pan, Hong-yi Zhou, Hong Chen, 2009, Journal of neurochemistry.

Antinociceptive Effect of Morphine, but not &mgr; Opioid Receptor Number, Is Attenuated in the Spinal Cord of Diabetic Rats

H. Pan, Shaorui Chen, 2003, Anesthesiology.

Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain.

W. Hittelman, H. Pan, Lingyong Li, 2016, Cell reports.

Histone methyltransferase G9a diminishes expression of cannabinoid CB1 receptors in primary sensory neurons in neuropathic pain

H. Pan, Hong Chen, Shaorui Chen, 2020, The Journal of Biological Chemistry.

Mastering tricyclic ring systems for desirable functional cannabinoid activity.

Claudio N Cavasotto, Ken Mackie, K. Mackie, 2013, European journal of medicinal chemistry.

Calcineurin Regulates Synaptic Plasticity and Nociceptive Transmission at the Spinal Cord Level

H. Pan, Shaorui Chen, Yuying Huang, 2021, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Potentiation of High Voltage–Activated Calcium Channels by 4-Aminopyridine Depends on Subunit Composition

Hongzhen Hu, De-Pei Li, H. Pan, 2014, Molecular Pharmacology.

Casein Kinase II Regulates N-Methyl-d-Aspartate Receptor Activity in Spinal Cords and Pain Hypersensitivity Induced by Nerve Injury

H. Byun, H. Pan, Hong-yi Zhou, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain

H. Pan, Shao‐Rui Chen, Youqing Cai, 2009, Journal of neurochemistry.

PII: S0304-3959(01)00398-0

R. James, A. Sandner-Kiesling, J. Eisenach, 2002 .

NMDA Receptors and Signaling in Chronic Neuropathic Pain

G. Laumet, H. Pan, Shaorui Chen, 2017 .

Opioid-Induced Long-Term Potentiation in the Spinal Cord Is a Presynaptic Event

H. Pan, Hong-yi Zhou, Hong Chen, 2010, The Journal of Neuroscience.

Ghrelin increases food intake and body weight by stimulating orexigenic agouti-related protein (AgRP)/neuropeptide Y (NPY) neurons and inhibiting anorexic pro-opiomelanocortin (POMC) neurons in the hypothalamus. Growth hormone secretagogue receptor (Ghsr) mediates the effect of ghrelin

Yuxiang Sun, De-Pei Li, H. Pan, 2017 .

LRRC8A-dependent volume-regulated anion channels contribute to ischemia-induced brain injury and glutamatergic input to hippocampal neurons

R. Sah, H. Pan, Shaorui Chen, 2020, Experimental Neurology.

δ-Opioid receptors in primary sensory neurons tonically restrain nociceptive input in chronic pain but do not enhance morphine analgesic tolerance

H. Pan, Hong Chen, Daozhong Jin, 2022, Neuropharmacology.

Mu opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/1.2 channels.

T. Finnegan, H. Pan, Shaorui Chen, 2006, Journal of neurophysiology.

Presynaptic NMDA receptors control nociceptive transmission at the spinal cord level in neuropathic pain

H. Pan, Shaorui Chen, M. Deng, 2019, Cellular and Molecular Life Sciences.

Increased C-Fiber Nociceptive Input Potentiates Inhibitory Glycinergic Transmission in the Spinal Dorsal Horn

H. Pan, Hong-Mei Zhang, Hong-yi Zhou, 2008, Journal of Pharmacology and Experimental Therapeutics.

Presynaptic mGluR5 receptor controls glutamatergic input through protein kinase C-NMDA receptors in paclitaxel-induced neuropathic pain.

H. Pan, Shaorui Chen, Jing-Dun Xie, 2017, The Journal of biological chemistry.

Transient Receptor Potential Vanilloid Type 1 Activation Down-regulates Voltage-gated Calcium Channels through Calcium-dependent Calcineurin in Sensory Neurons*

H. Pan, Shaorui Chen, Zi-Zhen Wu, 2005, Journal of Biological Chemistry.

Resistance to Morphine Analgesic Tolerance in Rats Deleted of TRPV1-Expressing Sensory Neurons

H. Pan, A. Prunean, Shaorui Chen, 2008 .

Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease

J. Peever, G. Homanics, K. Rice, 2014, Nature Neuroscience.

Resiniferatoxin Induces Paradoxical Changes in Thermal and Mechanical Sensitivities in Rats: Mechanism of Action

K. Alloway, H. Pan, G. Khan, 2003, The Journal of Neuroscience.

Differential Regulation of Primary Afferent Input to Spinal Cord by Muscarinic Receptor Subtypes Delineated Using Knockout Mice*

J. Wess, H. Pan, Hong Chen, 2014, The Journal of Biological Chemistry.

Effect of the μ Opioid on Excitatory and Inhibitory Synaptic Inputs to Periaqueductal Gray-Projecting Neurons in the Amygdala

T. Finnegan, H. Pan, Shaorui Chen, 2005, Journal of Pharmacology and Experimental Therapeutics.

Distinct Roles of Group III Metabotropic Glutamate Receptors in Control of Nociception and Dorsal Horn Neurons in Normal and Nerve-Injured Rats

H. Pan, Shaorui Chen, 2005, Journal of Pharmacology and Experimental Therapeutics.

Mitogen‐activated protein kinase signaling mediates opioid‐induced presynaptic NMDA receptor activation and analgesic tolerance

H. Pan, Hong Chen, Shaorui Chen, 2018, Journal of neurochemistry.

Distinct intrinsic and synaptic properties of pre‐sympathetic and pre‐parasympathetic output neurons in Barrington's nucleus

De-Pei Li, H. Pan, Shaorui Chen, 2013, Journal of neurochemistry.

Signalling pathway of nitric oxide in synaptic GABA release in the rat paraventricular nucleus

T. Finnegan, De-Pei Li, H. Pan, 2004, The Journal of physiology.

Adenosine inhibits paraventricular pre‐sympathetic neurons through ATP‐dependent potassium channels

De-Pei Li, H. Pan, Shaorui Chen, 2010, Journal of neurochemistry.

Activation of μ-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition

De-Pei Li, H. Pan, Yu-zhen Pan, 2004, Brain Research.

Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons.

T. Finnegan, De-Pei Li, H. Pan, 2004, The Journal of pharmacology and experimental therapeutics.

Regulating nociceptive transmission by VGluT2‐expressing spinal dorsal horn neurons

W. Hittelman, H. Pan, Hong Chen, 2018, Journal of neurochemistry.

Signaling Mechanisms Responsible for Muscarinic Potentiation of GABAergic Inputs to Spinal Dorsal Horn Neurons

H. Pan, Shaorui Chen, Hongmei Zhang, 2008 .

VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus.

De-Pei Li, H. Pan, Shaorui Chen, 2004, Journal of neurophysiology.

Functional Plasticity of Group II Metabotropic Glutamate Receptors in Regulating Spinal Excitatory and Inhibitory Synaptic Input in Neuropathic Pain

H. Pan, Hong-yi Zhou, Hong Chen, 2011, Journal of Pharmacology and Experimental Therapeutics.

Endogenously Released Glutamate Spinal GABAergic Transmission Through Increased Nociceptive Input Rapidly Modulates

Vivian M. Hernández, J. Wess, C. S. Chan, 2015 .

Increased nociceptive input rapidly modulates spinal GABAergic transmission through endogenously released glutamate.

H. Pan, Hong-Mei Zhang, Hong-yi Zhou, 2007, Journal of neurophysiology.

The α2δ-1-NMDA receptor complex and its potential as a therapeutic target for ischemic stroke

Tao Wu, H. Pan, Shaorui Chen, 2023, Frontiers in Neurology.

The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

David M. Maclean, V. Jayaraman, H. Pan, 2022, Cell reports.

Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1- and α2-Adrenergic Receptors.

Hong Chen, H. Pan, Shaorui Chen, 2023, ACS chemical neuroscience.

Rat Diaphragm Effect of Phasic Activation on Endplate Potential in

De-Pei Li, H. Pan, H. Kaminski, 2015 .

The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

David M. Maclean, V. Jayaraman, H. Pan, 2018, Cell reports.

Muscarinic Receptor Subtypes Afferents and Interneurons in the Spinal Cord by Regulation of Glutamate Release From Primary

J. Wess, H. Pan, Shao‐Rui Chen, 2015 .

Group III metabotropic glutamate receptors regulate hypothalamic presympathetic neurons through opposing presynaptic and postsynaptic actions in hypertension.

De-Pei Li, H. Pan, Shaorui Chen, 2020 .

Cardiac interstitial bradykinin release during ischemia is enhanced by ischemic preconditioning.

O. Carretero, H. Pan, G. Scicli, 2000, American journal of physiology. Heart and circulatory physiology.

Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats

D. Busija, J. Eisenach, H. Pan, 2000, Neuroscience.

Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats.

J. Eisenach, H. Pan, S. R. Chen, 1999, The Journal of pharmacology and experimental therapeutics.

Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats

H. Pan, G. Khan, S. R. Chen, 2002, Neuroscience.

Inhibition of β-ARK1 Ameliorates Morphine-induced Tolerance and Hyperalgesia Via Modulating the Activity of Spinal NMDA Receptors

Hong Chen, H. Pan, Yilin Zhao, 2017, Molecular Neurobiology.

Increased Spinal Cord Na+-K+-2Cl− Cotransporter-1 (NKCC1) Activity Contributes to Impairment of Synaptic Inhibition in Paclitaxel-induced Neuropathic Pain*

G. Laumet, H. Pan, Hong Chen, 2014, The Journal of Biological Chemistry.

Ghrelin receptors mediate ghrelin‐induced excitation of agouti‐related protein/neuropeptide Y but not pro‐opiomelanocortin neurons

Yuxiang Sun, De-Pei Li, H. Pan, 2017, Journal of neurochemistry.

a 2 d -1 – Dependent NMDA Receptor Activity in the Hypothalamus Is an Effector of Genetic-Environment Interactions That Drive Persistent Hypertension

De-Pei Li, H. Pan, Shaorui Chen, 2021 .

Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain.

W. Hittelman, H. Pan, Lingyong Li, 2016, Cell reports.

Protein kinase CK2 contributes to diminished small conductance Ca2+‐activated K+ channel activity of hypothalamic pre‐sympathetic neurons in hypertension

Hae-Ahm Lee, De-Pei Li, H. Pan, 2014, Journal of neurochemistry.

Stimulation of α1-adrenoceptors reduces glutamatergic synaptic input from primary afferents through GABAA receptors and T-type Ca2+ channels

H. Pan, H. Chen, Hong Chen, 2009, Neuroscience.

Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors

W. Hittelman, De-Pei Li, H. Pan, 2009, Journal of Pharmacology and Experimental Therapeutics.

Calcineurin regulates synaptic Ca2+‐permeable AMPA receptors in hypothalamic presympathetic neurons via α2δ‐1‐mediated GluA1/GluA2 assembly

Hong Chen, H. Pan, Shaorui Chen, 2024, The Journal of physiology.

Brain α2δ-1–Bound NMDA Receptors Drive Calcineurin Inhibitor–Induced Hypertension

H. Pan, Shaorui Chen, Jing-Jing Zhou, 2023, Circulation research.

Resistance to morphine analgesic tolerance in rats with deleted transient receptor potential vanilloid type 1-expressing sensory neurons

H. Pan, K. L. Welker, A. Prunean, 2007, Neuroscience.

DNA demethylation in the hypothalamus promotes transcription of Agtr1a and Slc12a2 and hypertension development

H. Pan, Shaorui Chen, Jing-Jing Zhou, 2023, The Journal of biological chemistry.

Nitric Oxide Derived from Neuronal NOS Inhibits Spinal Synaptic Transmission and Neuropathic Pain

H. Pan, Hong Chen, Xiao-gao Jin, 2015 .

Spinothalamic Tract Neurons Cuneothalamic Neurons: Comparison With Cardiopulmonary Sympathetic Input Excites Primate

H. Pan, M. Chester, Roger K.G. Moore, 2015 .

Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus

De-Pei Li, H. Pan, D.-P. Li, 2007, Neuroscience.