A. Ravji

The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis

Y. Pommier, L. Neckers, V. Factor, 2019, Nature Communications.

New fluorescence‐based high‐throughput screening assay for small molecule inhibitors of tyrosyl‐DNA phosphodiesterase 2 (TDP2)

Y. Pommier, K. Shi, E. Kiselev, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.

Y. Pommier, C. Marchand, K. Agama, 2018, Journal of medicinal chemistry.

Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.

Taresh K. Sethi, J. Freeman, Y. Pommier, 2017, Journal of medicinal chemistry.

The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis

Y. Pommier, L. Neckers, L. Jenkins, 2019, Nature Communications.

Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2).

Y. Pommier, C. Marchand, K. Agama, 2018, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).

Y. Pommier, C. Redon, C. Marchand, 2017, Journal of medicinal chemistry.

Novel Deazaflavin Analogues Potently Inhibited Tyrosyl DNA Phosphodiesterase 2 (TDP2) and Strongly Sensitized Cancer Cells toward Treatment with Topoisomerase II (TOP2) Poison Etoposide.

Y. Pommier, Jiashu Xie, E. Kiselev, 2019, Journal of medicinal chemistry.

Novel deazaflavin tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors.

Y. Pommier, Jiashu Xie, E. Kiselev, 2019, DNA repair.