Michael B Yaffe

发表

Focus Issue: Conquering the Data Mountain

Nancy R Gough, Michael B Yaffe, M. Yaffe, 2011, Science Signaling.

Engineered bromodomains to explore the acetylproteome

Forest M White, Michael B Yaffe, Bryan D Bryson, 2015, Proteomics.

Computational prediction of protein-protein interactions.

Michael B Yaffe, Tobias Ehrenberger, Lewis C Cantley, 2015, Methods in molecular biology.

PTMScout, a Web Resource for Analysis of High Throughput Post-translational Proteomics Studies*

Kristen M. Naegle, Melissa Gymrek, Forest M White, 2010, Molecular & Cellular Proteomics.

A Multivariate Computational Method to Analyze High-Content RNAi Screening Data

Jonathan Rameseder, Yogesh Dayma, Michael B Yaffe, 2015, Journal of biomolecular screening.

Novel at the library

Michael B Yaffe, M. Yaffe, 2004, Nature Methods.

A computational method for the analysis and prediction of protein:phosphopeptide‐binding sites

Bruce Tidor, Michael B Yaffe, Brian A Joughin, 2005, Protein science : a publication of the Protein Society.

Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.

Michael B Yaffe, M. Yaffe, T. Jacks, 2003, Molecular cell.

Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway

Birgit Schoeberl, Michael B Yaffe, Millie Shah, 2018, Science Signaling.

Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome

Michael B Yaffe, Shiva Gautam, D. Talmor, 2015, Shock.

TAZ as a novel enhancer of MyoD‐mediated myogenic differentiation

Michael B Yaffe, Jun-Ha Hwang, Jeong-Ho Hong, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase.

Michael B Yaffe, M. Yaffe, Hui Liu, 2003, Molecular cell.

Exploiting synthetic lethal interactions between DNA damage signaling, checkpoint control, and p53 for targeted cancer therapy.

Michael B Yaffe, M. Yaffe, Sandra Morandell, 2012, Progress in molecular biology and translational science.

A multivalent peptide library approach identifies a novel Shiga toxin inhibitor that induces aberrant cellular transport of the toxin

Michael B Yaffe, Miho Watanabe, M. Yaffe, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.

Michael B Yaffe, Michal Goldberg, Daniel Durocher, 2002, Molecular cell.

The Polo-Box Domain: A Molecular Integrator of Mitotic Kinase Cascades and Polo-like Kinase Function

Michael B Yaffe, Drew M. Lowery, M. Yaffe, 2004, Cell cycle.

Protein Regulation in Signal Transduction.

Michael B Yaffe, M. Yaffe, Michael J. Lee, 2016, Cold Spring Harbor perspectives in biology.

Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling

Otto Hudecz, Karl Mechtler, Andrea Musacchio, 2011, Science Signaling.

Robust co-regulation of tyrosine phosphorylation sites on proteins reveals novel protein interactions.

Kristen M. Naegle, Forest M White, Douglas A Lauffenburger, 2012, Molecular bioSystems.

The Scientific Drunk and the Lamppost: Massive Sequencing Efforts in Cancer Discovery and Treatment

Michael B Yaffe, M. Yaffe, 2013, Science Signaling.

Quantitative Phospho-proteomics to Investigate the Polo-like Kinase 1-Dependent Phospho-proteome*

Otto Hudecz, Karl Mechtler, Jonathan Rameseder, 2011, Molecular & Cellular Proteomics.

Systematic Phosphorylation Analysis of Human Mitotic Protein Complexes

Otto Hudecz, Karl Mechtler, Jean-Karim Hériché, 2011, Science Signaling.

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.

Michael B Yaffe, M. Yaffe, J. Lees, 2007, Cancer cell.

Computational prediction of protein-protein interactions.

Michael B Yaffe, M. Yaffe, J. Obenauer, 2004, Methods in molecular biology.

Structure and function of Polo-like kinases

Michael B Yaffe, Drew M. Lowery, M. Yaffe, 2005, Oncogene.

How do 14‐3‐3 proteins work? – Gatekeeper phosphorylation and the molecular anvil hypothesis

Michael B Yaffe, M. Yaffe, 2002, FEBS letters.

14-3-3 Proteins--a focus on cancer and human disease.

Michael B Yaffe, M. Yaffe, E. Wilker, 2004, Journal of molecular and cellular cardiology.

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells.

Kristen M. Naegle, Forest M White, Douglas A Lauffenburger, 2008, Molecular bioSystems.

TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation

Thomas Benjamin, Michael T. McManus, Nancy Hopkins, 2005, Science.

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

Michael B Yaffe, Drew M. Lowery, M. Yaffe, 2003, Science.

TAZ: a beta-catenin-like molecule that regulates mesenchymal stem cell differentiation.

Michael B Yaffe, Jeong-Ho Hong, M. Yaffe, 2006, Cell cycle.

Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates

Michael B Yaffe, Lewis C Cantley, M. Yaffe, 2003, Science.

Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles

Jeffrey Wyckoff, Michael B Yaffe, Paula T Hammond, 2018, Nature Communications.

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.

Michael B Yaffe, M. Yaffe, A. Elia, 2005, Molecular cell.

Distinct mechanisms act in concert to mediate cell cycle arrest

Bruce Tidor, Michael B Yaffe, Jared E Toettcher, 2009, Proceedings of the National Academy of Sciences.

The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function.

Michael B Yaffe, M. Yaffe, S. Smerdon, 2004, Annual review of biophysics and biomolecular structure.