N. Lai

发表

Increased Cardiac Adenylyl Cyclase Expression Is Associated With Increased Survival After Myocardial Infarction

P. Clopton, T. Tang, H. Hammond, 2006, Circulation.

Intracoronary delivery of an adenovirus encoding fibroblast growth factor-4 in myocardial ischemia: effect of serum antibodies and previous exposure to adenovirus.

N. Dalton, M. Gao, H. Hammond, 2006, Human gene therapy.

Dissociation between regional dysfunction and β-adrenergic receptor signaling in heart failure.

T. Anzai, M. Gao, H. Hammond, 1998, American journal of physiology. Heart and circulatory physiology.

New Signaling Pathways Associated with Increased Cardiac Adenylyl Cyclase 6 Expression: Implications for Possible CHF Therapy

M. Gao, T. Tang, N. Lai, 2008 .

Nitroprusside increases gene transfer associated with intracoronary delivery of adenovirus.

M. Gao, H. Hammond, D. Roth, 2004, Human gene therapy.

Recurrent Exposure to Subclinical Lipopolysaccharide Increases Mortality and Induces Cardiac Fibrosis in Mice

N. Dalton, V. Bhargava, P. Clopton, 2013, PloS one.

Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy.

M. Gao, H. Hammond, D. Entrikin, 1999, Circulation.

Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling

A. Firth, J. Yuan, M. Gao, 2008, Circulation.

Activation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice.

M. Gao, T. Tang, H. Hammond, 2008, Journal of the American College of Cardiology.

Significant alteration of liver metabolites by AAV8.Urocortin 2 gene transfer in mice with insulin resistance

M. Gao, T. Guo, H. Hammond, 2019, PloS one.

Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice.

T. Anzai, M. Gao, H. Hammond, 1999, Circulation.

Adenylylcyclase gene transfer increases function of the failing heart.

M. Gao, H. Hammond, Toshiyuki Takahashi, 2006, Human gene therapy.

Intracoronary Adenovirus Encoding Adenylyl Cyclase VI Increases Left Ventricular Function in Heart Failure

N. Dalton, P. Clopton, M. Gao, 2004, Circulation.

Preserved Cardiac Function despite Marked Impairment of cAMP Generation

Hong Wang, M. Gao, T. Tang, 2013, PloS one.

Beneficial Effects of Adenylyl Cyclase Type 6 (AC6) Expression Persist Using a Catalytically Inactive AC6 Mutant

A. Firth, J. Yuan, A. Miyanohara, 2011, Molecular Pharmacology.

Intracoronary Delivery of Adenovirus Encoding Adenylyl Cyclase VI Increases Left Ventricular Function and cAMP-Generating Capacity

K. Urasawa, M. Gao, H. Hammond, 2000, Circulation.

Cardiac-directed expression of a catalytically inactive adenylyl cyclase 6 protects the heart from sustained β-adrenergic stimulation

M. Gao, T. Guo, H. Hammond, 2017, PloS one.

Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to β–adrenergic stimulation

P. Han, M. Gao, T. Tang, 2006, Basic Research in Cardiology.

Functional magnetic resonance imaging for in vivo quantification of pulmonary hypertension in the Sugen 5416/hypoxia mouse

M. Scadeng, F. Murray, E. Breen, 2017, Experimental physiology.

Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression.

Andrew C. Li, G. Getz, T. Friedmann, 2011, Journal of the American College of Cardiology.

Urocortin 2 Gene Transfer for Systolic and Diastolic Dysfunction due to Chronically Increased Left Ventricular Pressure.

M. Gao, H. Hammond, Dimosthenis Giamouridis, 2022, Human gene therapy.

Blood Respiratory Properties and the Effect of Swimming on Blood Gas Transport in the Leopard Shark Triakis Semifasciata

L. Burnett, N. Lai, Ieffrey B. Graham, 1990 .

Urocortin 2 Gene Transfer Reduces the Adverse Effects of a Western Diet on Cardiac Function in Mice.

M. Gao, T. Guo, H. Hammond, 2019, Human gene therapy.

Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain (C1C2) Attenuates Deleterious Effects of Pressure Overload.

M. Gao, T. Guo, H. Hammond, 2019, Human gene therapy.

1 - Elasmobranch Cardiovascular System

R. Brill, N. Lai, 2015 .

Plasma catecholamine levels as indicators of the post-release survivorship of juvenile pelagic sharks caught on experimental drift longlines in the Southern California Bight

J. Graham, B. Kennedy, C. Sepulveda, 2007 .

Hemodynamics and Blood Properties of the Shortfin Mako Shark (Isurus oxyrinchus)

J. Graham, Keith E Korsmeyer, S. Katz, 1997 .

Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer.

A. Miyanohara, M. Gao, T. Tang, 2012, Human gene therapy.

Respiratory, Blood, and Heart Enzymatic Adaptations of Sebastolobus alascanus (Scorpaenidae; Teleostei) to the Oxygen Minimum Zone: A Comparative Study.

G. Somero, J. Graham, N. Lai, 1992, The Biological bulletin.

Comparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer.

A. Miyanohara, M. Gao, T. Tang, 2012, Human gene therapy methods.

Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6

K. Krobert, F. Levy, H. Hammond, 2019, PloS one.

Spiracular air breathing in polypterid fishes and its implications for aerial respiration in stem tetrapods

L. Frank, J. Long, J. Graham, 2014, Nature Communications.

Digital image analysis of shark gills: modeling of oxygen transfer in the domain of time.

V. Bhargava, R. Shabetai, J. Graham, 1992, American Journal of Physiology.

Mechanisms of venous return and ventricular filling in elasmobranch fish.

V. Bhargava, R. Shabetai, J. Graham, 1996, The American journal of physiology.

Elevated pericardial pressure and cardiac output in the leopard shark Triakis semifasciata during exercise: the role of the pericardioperitoneal canal

R. Shabetai, J. Graham, W. Lowell, 1989 .

Pericardial and vascular pressures and blood flow in the albacore tuna, Thunnus alalunga.

R. Laurs, J. Graham, W. Lowell, 1987, Experimental biology.

Tuna aerobic swimming performance: Physiological and environmental limits based on oxygen supply and demand

H. Dewar, J. Graham, Keith E Korsmeyer, 1996 .

Heart rate and stroke volume contribution to cardiac output in swimming yellowfin tuna: response to exercise and temperature.

R. Shadwick, J. Graham, Keith E Korsmeyer, 1997, The Journal of experimental biology.

Metabolic rate, heart rate, and tailbeat frequency during sustained swimming in the leopard shark Triakis semifasciata.

J. Scharold, J. Graham, J B Graham, 1989, Experimental biology.

Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency

V. A. Huu, M. Gao, T. Guo, 2019, Molecular therapy. Methods & clinical development.

One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance.

T. Ciaraldi, A. Miyanohara, M. Gao, 2016, JCI insight.

Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice

A. Miyanohara, M. Gao, T. Guo, 2015, Human gene therapy.

Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.

N. Dalton, A. Miyanohara, H. Patel, 2013, Human gene therapy.

Nonmitochondrial oxygen utilization by rabbit blastocysts and surface production of superoxide radicals.

N. Lai, C. Manes, 1995, Journal of reproduction and fertility.

Dissociation between regional dysfunction and beta-adrenergic receptor signaling in heart failure.

T. Anzai, M. Gao, H. Hammond, 1998, American Journal of Physiology.

The aerobic capacity of tunas: Adaptation for multiple metabolic demands

H. Dewar, J. Graham, Keith E Korsmeyer, 1996 .

Cardiac-directed expression of adenylyl cyclase VI facilitates atrioventricular nodal conduction.

A. Iwasa, A. Hassankhani, S. Narayan, 2006, Journal of the American College of Cardiology.

Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation

M. Gao, T. Guo, H. Hammond, 2016, JACC. Basic to translational science.

Clinical Evaluation of Heart Failure: Agreement among Tests

V. Bhargava, R. Xu, H. Hammond, 2014, PloS one.

Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.

M. Gao, T. Tang, T. Guo, 2010, Journal of the American College of Cardiology.

Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical Trial.

Amit N. Patel, C. Yancy, N. Dalton, 2016, JAMA cardiology.

Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.

A. Firth, J. Yuan, M. Gao, 2011, Journal of the American College of Cardiology.

New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.

M. Gao, T. Tang, H. Hammond, 2007, Trends in cardiovascular medicine.

Urocortin 3 Gene Transfer Increases Function of the Failing Murine Heart.

A. Miyanohara, M. Gao, T. Guo, 2019, Human gene therapy.

Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.

A. McCulloch, M. Gao, T. Tang, 2013, Journal of molecular and cellular cardiology.

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.

A. Firth, J. Yuan, M. Gao, 2011, Biochemical and biophysical research communications.

Signal peptide increases the efficacy of angiogenic gene transfer for treatment of myocardial ischemia.

M. Gao, H. Hammond, N. C. Lai, 2005, Human gene therapy.

Urocortin2 Gene Transfer Improves Heart Function in Aged Mice.

A. Miyanohara, M. Gao, T. Guo, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Echocardiographic and Hemodynamic Determinations of the Ventricular Filling Pattern in Some Teleost Fishes

N. Dalton, V. Bhargava, R. Shabetai, 1998, Physiological Zoology.

Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal

A. Miyanohara, M. Gao, T. Guo, 2018, JACC. Basic to translational science.

Indirect intracoronary delivery of adenovirus encoding adenylyl cyclase increases left ventricular contractile function in mice.

J. Feramisco, M. Gao, H. Hammond, 2004, American journal of physiology. Heart and circulatory physiology.

Oxygen utilization and the branchial pressure gradient during ram ventilation of the shortfin mako, Isurus oxyrinchus: is lamnid shark–tuna convergence constrained by elasmobranch gill morphology?

J. Graham, Kristina B Bull, N. Lai, 2012, Journal of Experimental Biology.

Effects of Urocortin 2 Gene Transfer on Glucose Disposal in Insulin-Resistant db/db Mice on Metformin.

M. Gao, T. Guo, H. Hammond, 2023, Human gene therapy.

Increased regional function and perfusion after intracoronary delivery of adenovirus encoding fibroblast growth factor 4: report of preclinical data.

N. Dalton, M. Gao, H. Hammond, 2004, Human gene therapy.

Oxygen transport and cardiovascular responses to exercise in the yellowfin tuna Thunnus albacares.

R. Shadwick, J. Graham, Keith E Korsmeyer, 1997, The Journal of experimental biology.

Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.

M. Gao, T. Tang, H. Hammond, 2010, Journal of the American College of Cardiology.