Christin Völkner

发表

Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the NPC2 Mutations c.58G>T/c.140G>T

M. Frech, A. Hermann, Maik Liedtke, 2021, International journal of molecular sciences.

Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells

M. Frech, J. Lukas, A. Hermann, 2020, International journal of molecular sciences.

Generation of induced pluripotent stem cell lines AKOSi002-A and AKOSi003-A from symptomatic female adults with Wilson disease.

M. Frech, H. Murua Escobar, A. Rolfs, 2020, Stem cell research.

Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism

M. Frech, O. von Bohlen und Halbach, A. Rolfs, 2020, International journal of molecular sciences.

Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1

M. Frech, A. Hermann, Maik Liedtke, 2021, International journal of molecular sciences.

Determination of the Pathological Features of NPC1 Variants in a Cellular Complementation Test

M. Frech, P. Bauer, M. Lerch, 2019, International journal of molecular sciences.

Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical Phenotype of Niemann-Pick Type C1 Disease

M. Frech, A. Hermann, Maik Liedtke, 2021, International journal of molecular sciences.

Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems

M. Frech, J. Lukas, S. Pantoom, 2022, Cells.

Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann–Pick Disease Type C

M. Frech, A. Hermann, Maik Liedtke, 2022, Cells.

Generation of the Niemann-Pick type C2 patient-derived iPSC line AKOSi001-A.

M. Frech, H. Murua Escobar, J. Lukas, 2019, Stem cell research.

Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs*15/p.Gly992Arg and of an iPSC line (AKOSi005-A) from a female adult control individual.

M. Frech, J. Bullerdiek, H. M. Escobar, 2020, Stem cell research.

Generation of two induced pluripotent stem cell lines from a female adult homozygous for the Wilson disease associated ATP7B variant p.H1069Q (AKOSi008-A) and a healthy control (AKOSi009-A).

M. Frech, H. Murua Escobar, J. Bullerdiek, 2020, Stem cell research.