H. Fujiwara

发表

Endogenous acetylcholine regulates neuronal and astrocytic vascular endothelial growth factor expression levels via different acetylcholine receptor mechanisms

Kinzo Matsumoto, J. Oka, K. Kimura, 2018, Neurochemistry International.

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism

Kinzo Matsumoto, S. Awale, D. F. Dibwe, 2019, PloS one.

Kihito prevents corticosterone-induced brain dysfunctions in mice

Kinzo Matsumoto, T. Yabe, Kazufumi Toume, 2021, Journal of traditional and complementary medicine.

Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(1) receptors: elucidation using organic hippocampal slice cultures.

K. Tsuneyama, Kinzo Matsumoto, T. Miyata, 2013, European journal of pharmacology.

Nobiletin, a flavone from Citrus depressa, induces gene expression and increases the protein level and activity of neprilysin in SK-N-SH cells.

J. Kimura, Y. Ohizumi, M. Sakamoto, 2014, Canadian journal of physiology and pharmacology.

Protective effects of Bacopa monnieri on ischemia-induced cognitive deficits in mice: the possible contribution of bacopaside I and underlying mechanism.

Kinzo Matsumoto, H. Fujiwara, T. Van Nguyen, 2015, Journal of ethnopharmacology.

Characteristics of nobiletin-mediated alteration of gene expression in cultured cell lines.

J. Kimura, Y. Ohizumi, K. Nemoto, 2013, Biochemical and biophysical research communications.

Effects of Puerarin on the Ovariectomy-Induced Depressive-Like Behavior in ICR Mice and Its Possible Mechanism of Action

K. Umehara, H. Noguchi, Kinzo Matsumoto, 2019, Molecules.

Social Isolation Stress-Induced Fear Memory Deficit is Mediated by Down-Regulated Neuro-Signaling System and Egr-1 Expression in the Brain

K. Tsuneyama, Kinzo Matsumoto, H. Fujiwara, 2014, Neurochemical Research.

- Mangostin Induces Ca 2 +-ATPase-Dependent Apoptosis via Mitochondrial Pathway in PC 12 Cells

Y. Ohizumi, Ayumi Sato, H. Fujiwara, 2004 .

Alpha-mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells.

Y. Ohizumi, Ayumi Sato, H. Fujiwara, 2004, Journal of pharmacological sciences.

Brasilibactin A, a cytotoxic compound from actinomycete Nocardia brasiliensis.

Y. Ohizumi, M. Tsuda, S. Oka, 2005, Journal of natural products.

Potent apoptotic effects of saponins from Liliaceae plants in L1210 cells

Y. Ohizumi, Y. Mimaki, Y. Sashida, 2002, The Journal of pharmacy and pharmacology.

Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism.

Y. Ohizumi, Y. Mimaki, Y. Sashida, 2001, Canadian journal of physiology and pharmacology.

Chemical constituents and absolute configuration of megastigmanes’ isolated from Sedum sarmentosum Bunge

Kinzo Matsumoto, S. Awale, D. T. Nguyen, 2020, Natural product research.

Ophiobolin A, a Novel Apoptosis‐inducing Agent from Fungus Strain f‐7438

Y. Ohizumi, M. Ishizuka, H. Kumagai, 2000 .

Honeybee royal jelly and nobiletin stimulate CRE-mediated transcription in ERK-independent and -dependent fashions, respectively, in PC12D cells.

Y. Ohizumi, M. Sakamoto, K. Yamaguchi, 2011, Journal of pharmacological sciences.

Post-weaning social isolation of mice: A putative animal model of developmental disorders.

Kinzo Matsumoto, T. Yabe, Ryota Araki, 2019, Journal of pharmacological sciences.

Kami-shoyo-san ameliorates sociability deficits in ovariectomized mice, a putative female model of autism spectrum disorder, via facilitating dopamine D1 and GABAA receptor functions.

E. Dong, Kinzo Matsumoto, S. Awale, 2019, Journal of ethnopharmacology.

Kamiuntanto increases prefrontal extracellular serotonin levels and ameliorates depression-like behaviors in mice.

Kinzo Matsumoto, T. Yabe, Y. Ago, 2019, Journal of pharmacological sciences.

Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β‐amyloid proteins

Akihiko Takashima, Hiroyuki Arai, Sumihiro Maeda, 2006, Journal of neuroscience research.

A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid β proteins in vitro and in vivo

H. Arai, N. Yaegashi, K. Sekiguchi, 2009, Alzheimer's & Dementia.

A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6‐penta‐O‐galloyl‐β‐d‐glucopyranose have potent anti‐aggregation effects on Alzheimer’s amyloid β proteins in vitro and in vivo

S. Maeda, H. Arai, M. Higuchi, 2009, Journal of neurochemistry.

Kampo formulations, chotosan, and yokukansan, for dementia therapy: existing clinical and preclinical evidence.

Kinzo Matsumoto, J. Oka, H. Fujiwara, 2013, Journal of pharmacological sciences.

Effects of the traditional Chinese herbal medicine Yi-Gan San for cholinesterase inhibitor-resistant visual hallucinations and neuropsychiatric symptoms in patients with dementia with Lewy bodies.

H. Arai, N. Tomita, K. Furukawa, 2005, The Journal of clinical psychiatry.

A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients.

H. Arai, Hidetada Sasaki, N. Tomita, 2005, The Journal of clinical psychiatry.

Alterations in the Levels of Amyloid-β, Phospholipid Hydroperoxide, and Plasmalogen in the Blood of Patients with Alzheimer's Disease: Possible Interactions between Amyloid-β and These Lipids.

H. Arai, K. Nakagawa, K. Furukawa, 2015, Journal of Alzheimer's disease : JAD.

Quinoline and Benzimidazole Derivatives: Candidate Probes for In Vivo Imaging of Tau Pathology in Alzheimer's Disease

H. Arai, N. Okamura, Masako Suzuki, 2005, The Journal of Neuroscience.

Docosahexaenoic acid disrupts in vitro amyloid β1‐40 fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer’s disease model rats

H. Arai, T. Miyazawa, O. Shido, 2008, Journal of neurochemistry.

Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells.

H. Nakamura, Y. Ohizumi, K. Furukawa, 2001, European journal of pharmacology.

Memory/Learning, Dementia, and Kampo

Kinzo Matsumoto, H. Fujiwara, 2016 .

RA-VII, a cyclic depsipeptide, changes the conformational structure of actin to cause G2 arrest by the inhibition of cytokinesis.

Hironori Fujiwara, Y. Ohizumi, Koichi Takeya, 2004, Cancer letters.

Bacopa monnieri Ameliorates Memory Deficits in Olfactory Bulbectomized Mice: Possible Involvement of Glutamatergic and Cholinergic Systems

Kinzo Matsumoto, Feng Li, P. Do, 2013, Neurochemical Research.

Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β

H. Arai, Kinzo Matsumoto, Y. Kudo, 2018, Journal of traditional and complementary medicine.

IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells

T. Isobe, Y. Ohizumi, T. Shinkawa, 2004, Journal of Pharmacology and Experimental Therapeutics.

Extraction of nobiletin from Citrus Unshiu peels by supercritical fluid and its CRE-mediated transcriptional activity.

Y. Ohizumi, H. Inomata, Yoshiyuki Sato, 2017, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Antidepressant-like effect of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action.

Kinzo Matsumoto, T. Ishikawa, Y. Higuchi, 2014, Journal of ethnopharmacology.

Butea superba-induced amelioration of cognitive and emotional deficits in olfactory bulbectomized mice and putative mechanisms underlying its actions.

Kinzo Matsumoto, T. Ishikawa, Y. Higuchi, 2014, Journal of pharmacological sciences.

Polygalae radix extract ameliorates behavioral and neuromorphological abnormalities in chronic corticosterone‐treated mice

Kinzo Matsumoto, T. Yabe, Kazufumi Toume, 2018, Traditional & Kampo Medicine.

Possible involvement of VEGF signaling system in rescuing effect of endogenous acetylcholine on NMDA-induced long-lasting hippocampal cell damage in organotypic hippocampal slice cultures

Kinzo Matsumoto, H. Fujiwara, Chikako Inada, 2014, Neurochemistry International.

Bacopa monnieri (L.) Ameliorates Cognitive Deficits Caused in a Trimethyltin-Induced Neurotoxicity Model Mice.

Kinzo Matsumoto, K. Ogita, Taro Yamaguchi, 2019, Biological & pharmaceutical bulletin.

Decrease in endogenous brain allopregnanolone induces autism spectrum disorder (ASD)-like behavior in mice: A novel animal model of ASD

Kinzo Matsumoto, S. Awale, D. F. Dibwe, 2017, Behavioural Brain Research.

Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

Kinzo Matsumoto, S. Awale, T. Yabe, 2017, BMC Complementary and Alternative Medicine.

Bacopa monnieri Ameliorates Memory Deficits in Olfactory Bulbectomized Mice: Possible Involvement of Glutamatergic and Cholinergic Systems

Kinzo Matsumoto, Feng Li, P. Do, 2013, Neurochemical Research.

Sansoninto, a traditional herbal medicine, ameliorates behavioral abnormalities and down-regulation of early growth response-1 expression in mice exposed to social isolation stress

Kinzo Matsumoto, S. Awale, T. Yabe, 2017, Journal of Traditional and Complementary Medicine.

Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia.

Shiro Watanabe, Kinzo Matsumoto, Feng Li, 2015, Journal of pharmaceutical and biomedical analysis.

Limonene Enhances the cAMP Response Element (CRE)-Dependent Transcriptional Activity Activated via Adenosine A2 A Receptor in a Neural-Crest Derived Cell Line, PC-12

Y. Ohizumi, N. Uozumi, H. Inomata, 2016, Planta Medica International Open.