Peter Drückes

发表

A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis.

J. Mestan, G. Martiny-Baron, C. Schnell, 2016, Journal of medicinal chemistry.

Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.

S. Laufer, P. Koch, U. Rothbauer, 2015, Journal of medicinal chemistry.

Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound.

D. Rognan, C. Bissantz, G. Folkers, 2002, Journal of medicinal chemistry.

Selective inhibitors of the Janus kinase Jak3--Are they effective?

G. Thoma, H. Zerwes, Peter Drückes, 2014, Bioorganic & medicinal chemistry letters.

Jak1 has a dominant role over Jak3 in signal transduction through γc-containing cytokine receptors.

I. Behrmann, G. Thoma, H. Zerwes, 2011, Chemistry & biology.

The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold*

N. Schmiedeberg, G. Fendrich, T. Troxler, 2015, The Journal of Biological Chemistry.

Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors.

G. Martiny-Baron, G. Fendrich, T. Troxler, 2016, Journal of medicinal chemistry.

Discovery of novel indolinone-based, potent, selective and brain penetrant inhibitors of LRRK2.

T. Troxler, K. Zimmermann, D. Shimshek, 2013, Bioorganic & medicinal chemistry letters.

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension.

P. Furet, I. Konstantinova, A. Saunders, 2016, Journal of medicinal chemistry.

Syk inhibitors with high potency in presence of blood.

Jianwei Che, E. Vangrevelinghe, Christian C. Lee, 2014, Bioorganic & medicinal chemistry letters.