Jiao Shen

Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity

yang-xin fu, Jiankun Zhu, Yong Liang, 2021, Cell Research.

Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance

Zhichen Sun, Haidong Dong, yang-xin fu, 2018, Nature Communications.

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer

Zhichen Sun, yang-xin fu, Jiankun Zhu, 2022, Nature Cell Biology.

Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance

Zhichen Sun, Haidong Dong, yang-xin fu, 2018, Nature Communications.

An engineered concealed IL-15-R elicits tumor-specific CD8+T cell responses through PD-1-cis delivery

Yangbo Fu, Yong Liang, Jingya Guo, 2022, The Journal of experimental medicine.

Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8+T cells for systemic antitumor responses

Yangbo Fu, Hua Peng, Diyuan Xue, 2024, Nature communications.