M. Cinar

Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma.

S. Alkan, H. Amin, F. Hamedani, 2014, Leukemia research.

Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis.

S. Alkan, H. Amin, B. Cinar, 2013, Leukemia research.

Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype

I. Lossos, Y. Natkunam, C. Flowers, 2017, Oncogene.

Retrotransposons facilitate the tissue-specific horizontal transfer of circulating tumor DNA between human cells

I. Lossos, S. Lonial, B. Vardarajan, 2022, bioRxiv.

Concurrent inhibition of MYC and BCL2 is a potentially effective treatment strategy for double hit and triple hit B-cell lymphomas.

S. Alkan, R. Pillai, B. Cinar, 2015, Leukemia research.

Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)

S. Lonial, R. Vij, Zhengjia Chen, 2018, Blood.