Lingtian Zhang

发表

Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of RET: Design, synthesis and biological evaluation.

Naga Rajiv Lakkaniga, Y. Leung, Hong‐yu Li, 2020, European journal of medicinal chemistry.

Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.

Naga Rajiv Lakkaniga, M. Santoro, P. Knowles, 2022, Journal of medicinal chemistry.

Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases

Naga Rajiv Lakkaniga, M. Santoro, P. Salerno, 2021, Scientific Reports.

Sulfation of benzyl alcohol by the human cytosolic sulfotransferases (SULTs): a systematic analysis

M. Suiko, Y. Sakakibara, Ming-yih Liu, 2016, Journal of applied toxicology : JAT.

Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation.

M. Santoro, F. Gosselet, F. Carlomagno, 2021, European journal of medicinal chemistry.

Intramolecular cyclization of imidazo[1,2-a]pyridines via a silver mediated/palladium catalyzed C–H activation strategy

Hong‐yu Li, D. Basak, B. Frett, 2019, Organic Chemistry Frontiers.

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

Naga Rajiv Lakkaniga, N. Shah, Hong‐yu Li, 2018, Scientific Reports.

Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts.

Naga Rajiv Lakkaniga, Hong‐yu Li, B. Frett, 2018, Chemical communications.

Discovery of imidazo[1,2-a]pyridine-thiophene derivatives as FLT3 and FLT3 mutants inhibitors for acute myeloid leukemia through structure-based optimization of an NEK2 inhibitor.

Naga Rajiv Lakkaniga, Y. Leung, N. Shah, 2021, European journal of medicinal chemistry.

Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

Naga Rajiv Lakkaniga, M. Santoro, N. McDonald, 2020, Journal of medicinal chemistry.

Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression.

Naga Rajiv Lakkaniga, Hong‐yu Li, B. Frett, 2020, European journal of medicinal chemistry.

Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis.

M. Suiko, Y. Sakakibara, Chunyang Zhou, 2015, Journal of pharmacological sciences.

Discovery of fused benzimidazole-imidazole autophagic flux inhibitors for treatment of triple-negative breast cancer.

Zhigang Xu, Zhong-Zhu Chen, Jingyuan Wen, 2022, European journal of medicinal chemistry.