E. Hicken

发表

Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity.

J. Blake, J. Christensen, B. Brandhuber, 2018, ACS medicinal chemistry letters.

Chapter 2 Synthesis of geldanamycin using glycolate aldol reactions

M. Andrus, E. Meredith, E. Hicken, 2005 .

Selective synthesis of the para-quinone region of geldanamycin.

J. Cannon, M. Andrus, Bryon Simmons, 2003, Organic letters.

Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions.

B. V. Soma Sekhar, M. Andrus, Bryon Simmons, 2002, Organic letters.

Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer

J. Blake, J. Christensen, G. Vigers, 2020 .

Stereoselective synthesis of woody fragrances related to georgyone and arborone.

E. Corey, E. Hicken, 2008, Organic letters.

Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation.

M. Andrus, Wei-Ping Ma, Bryon Simmons, 2003, The Journal of organic chemistry.

Phase-transfer-catalyzed asymmetric acylimidazole alkylation.

Morgan J. Gainer, Daniel Dodson, M. Andrus, 2007, Organic letters.

Total synthesis of the hydroxyketone kurasoin A using asymmetric phase-transfer alkylation.

M. Andrus, J. C. Stephens, D. K. Bedke, 2006, The Journal of organic chemistry.

Asymmetric phase-transfer catalyzed glycolate alkylation, investigation of the scope, and application to the synthesis of (-)-ragaglitazar.

M. Andrus, J. C. Stephens, D. K. Bedke, 2005, The Journal of organic chemistry.

Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability.

J. E. Robinson, J. Lyssikatos, R. K. DeLisle, 2014, ACS medicinal chemistry letters.

Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation.

John A. Robinson, E. Gelfand, L. Carter, 2012, American journal of respiratory cell and molecular biology.

Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer.

G. Vigers, J. Gaudino, Jennifer N. Otten, 2020, Journal of medicinal chemistry.

Phase-transfer-catalyzed asymmetric glycolate alkylation.

M. Andrus, J. C. Stephens, E. Hicken, 2004, Organic letters.

Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA.

C. E. Wise, J. Gaudino, E. Hicken, 2024, Journal of medicinal chemistry.