Rajaram Azad

发表

Molecular dynamic simulations based discovery and development of thiazolidin-4-one derivatives as EGFR inhibitors targeting resistance in non-small cell lung cancer (NSCLC)

Shailee V. Tiwari, P. Wakte, D. Lokwani, 2022, Journal of biomolecular structure & dynamics.

Green synthesis and inhibitory effect of novel quinoline based thiazolidinones on the growth of MCF-7 human breast cancer cell line by G2/M cell cycle arrest

C. Gill, A. Sarkate, Vidya S. Dofe, 2018, Research on Chemical Intermediates.

Betulinic acid derivatives: a new class of α-glucosidase inhibitors and LPS-stimulated nitric oxide production inhibition on mouse macrophage RAW 264.7 cells

Ramesh Bokam, Nageswara Rao Yalavarthi, M. G. Ponnapalli, 2019, Natural product research.

Synthesis and evaluation of novel sulfonamide analogues of 6/7-aminoflavones as anticancer agents via topoisomerase II inhibition.

Shailee V. Tiwari, D. Lokwani, A. Sarkate, 2020, Bioorganic & medicinal chemistry letters.

Efficient Synthesis of Densely Functionalized Pyrido[2,3-d]Pyrimidines via Three-component One-pot Domino Knoevenagel aza-Diels Alder Reaction and Induces Apoptosis in Human Cancer Cell Lines via Inhibiting Aurora A and B Kinases

M. Bhosle, G. Bondle, A. Sarkate, 2022, Polycyclic Aromatic Compounds.

Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions.

Shailee V. Tiwari, D. Lokwani, A. Sarkate, 2022, European journal of medicinal chemistry.

Design, synthesis, biological evaluation and in silico studies of EGFR inhibitors based on 4-oxo-chromane scaffold targeting resistance in non-small cell lung cancer (NSCLC)

Shailee V. Tiwari, P. Wakte, A. Sarkate, 2022, Medicinal Chemistry Research.

Design, Synthesis and Biological Evaluation of Tetrahydrodibenzo[b,g][1,8]napthyridinones as Potential Anticancer Agents and Novel Aurora Kinases Inhibitors

Asha V. Chate, G. Bondle, A. Sarkate, 2021 .

One pot synthesis, in silico study and evaluation of some novel flavonoids as potent topoisomerase II inhibitors.

Shailee V. Tiwari, J. Sangshetti, Suneel S. Dodamani, 2021, Bioorganic & medicinal chemistry letters.

Novel quinoline-based oxadiazole derivatives induce G2/M arrest and apoptosis in human breast cancer MCF-7 cell line

C. Gill, A. Sarkate, Vidya S. Dofe, 2017, Research on Chemical Intermediates.

Structure Based Library Design (SBLD) for new 1,4-dihydropyrimidine scaffold as simultaneous COX-1/COX-2 and 5-LOX inhibitors.

P. Reddanna, D. Shinde, D. Lokwani, 2015, Bioorganic & medicinal chemistry.

Evaluation of anti-inflammatory and immunomodulatory effects of Premna integrifolia extracts and assay-guided isolation of a COX-2/5-LOX dual inhibitor.

P. Reddanna, A. Gupta, Rajaram Azad, 2018, Fitoterapia.

Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa

M. Kamal, N. S. Yarla, A. Srivastava, 2017, Oxidative medicine and cellular longevity.

New amide linked dimeric 1,2,3-triazoles bearing aryloxy scaffolds as a potent antiproliferative agents and EGFR tyrosine kinase phosphorylation inhibitors.

Shailee V. Tiwari, D. Lokwani, A. Sarkate, 2019, Bioorganic & medicinal chemistry letters.

Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa

P. Reddanna, B. Bodo, K. K. Reddy, 2015, Natural product communications.

Computational and Synthetic approach with Biological Evaluation of Substituted Quinoline derivatives as small molecule L858R/T790M/C797S triple mutant EGFR inhibitors targeting resistance in Non-Small Cell Lung Cancer (NSCLC).

Shailee V. Tiwari, P. Wakte, A. Sarkate, 2021, Bioorganic chemistry.

N-Benzylation of 6-aminoflavone by reductive amination and efficient access to some novel anticancer agents via topoisomerase II inhibition

D. Lokwani, A. Sarkate, S. Tiwari, 2020, Molecular Diversity.

N-Benzylation of 6-aminoflavone by reductive amination and efficient access to some novel anticancer agents via topoisomerase II inhibition

Shailee V. Tiwari, D. Lokwani, A. Sarkate, 2020, Molecular Diversity.

In vitro evaluation of anticancer effects of different probiotic strains on HCT‐116 cell line

P. Reddanna, J. Ahire, Sandhya Singh, 2021, Journal of applied microbiology.

Free energy perturbation guided Synthesis with Biological Evaluation of Substituted Quinoline derivatives as small molecule L858R/T790M/C797S mutant EGFR inhibitors targeting resistance in Non-Small Cell Lung Cancer (NSCLC).

P. Wakte, A. Sarkate, S. Tiwari, 2021, Bioorganic chemistry.

Design and synthesis of novel conformationally constrained 7,12-dihydrodibenzo[b,h][1,6] naphthyridine and 7H-Chromeno[3,2-c] quinoline derivatives as topoisomerase I inhibitors: In vitro screening, molecular docking and ADME predictions.

Shailee V. Tiwari, D. Lokwani, A. Sarkate, 2021, Bioorganic chemistry.