S. Takagi

发表

LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B.

S. Iwasaki, T. Nomura, Kazuhide Nakamura, 2017, Cancer research.

Antitumor Activity of TAK-285, an Investigational, Non-Pgp Substrate HER2/EGFR Kinase Inhibitor, in Cultured Tumor Cells, Mouse and Rat Xenograft Tumors, and in an HER2-Positive Brain Metastasis Model

T. Ishikawa, Y. Ohta, Akiko Nakayama, 2013, Journal of Cancer.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2018, Nature Communications.

JARID1B is a luminal lineage-driving oncogene in breast cancer.

Carlos Caldas, Charles J. Vaske, Hanfei Sun, 2014, Cancer cell.

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

R. Hara, M. Yabuki, Naoki Tomita, 2016, Molecular Cancer Therapeutics.

Correction: Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication

K. Toyoshima, H. Miyashita, A. Hayashi, 2017, Oncogenesis.

Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication

K. Toyoshima, H. Miyashita, A. Hayashi, 2017, Oncogenesis.

HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285

T. Ishikawa, H. Banno, Y. Ohta, 2014, Oncoscience.

Wnt/β‐catenin signaling suppresses apoptosis in low serum medium and induces morphologic change in rodent fibroblasts

K. Shimotohno, T. Chiba, M. Hijikata, 2002, International journal of cancer.

p73β, a Variant of p73, Enhances Wnt/β-Catenin Signaling in Saos-2 Cells

K. Shimotohno, T. Chiba, M. Hijikata, 2001 .

Overproduced p73α activates a minimal promoter through a mechanism independent of its transcriptional activity

K. Shimotohno, M. Hijikata, Y. Ueda, 2001 .

New p73 variants with altered C-terminal structures have varied transcriptional activities

Makoto Hijikata, Tsutomu Chiba, K. Shimotohno, 1999, Oncogene.

Transcriptional activities of p73 splicing variants are regulated by inter-variant association.

K. Shimotohno, T. Chiba, M. Hijikata, 2001, The Biochemical journal.

Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors.

Yoshikazu Ohta, Tomoyasu Ishikawa, Terufumi Takagi, 2013, ACS medicinal chemistry letters.

p73beta, a variant of p73, enhances Wnt/beta-catenin signaling in Saos-2 cells.

K. Shimotohno, T. Chiba, M. Hijikata, 2001, Biochemical and biophysical research communications.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2020, Nature Communications.