T. Kohn

发表

P3 cap modified Phe*-Ala series BACE inhibitors.

D. Timm, P. May, Shu-Hui Chen, 2004, Bioorganic & medicinal chemistry letters.

Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents.

R. Hungate, W. Shen, J. Jaén, 2008, Bioorganic & medicinal chemistry letters.

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

A. Cheng, P. Coward, J. Medina, 2016, ACS medicinal chemistry letters.

Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors

D. Whittington, Yi Chen, K. Miner, 2012 .

Discovery and in vivo evaluation of dual PI3Kβ/δ inhibitors.

D. Whittington, Yi Chen, K. Miner, 2012, Journal of medicinal chemistry.

Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 5. Potency, efficacy, and pharmacokinetic properties of modified C-3 side chain derivatives.

R. W. Harper, N. Chirgadze, M. J. Fisher, 2000, Journal of medicinal chemistry.

Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation.

R. W. Harper, N. Chirgadze, S. Briggs, 1997, Journal of medicinal chemistry.

Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds.

J. Wikel, K. Takeuchi, J. A. Jakubowski, 1998, Journal of medicinal chemistry.

Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 2. Design, synthesis, and evaluation of a novel series of phenyl oxazole derivatives.

K. Takeuchi, J. A. Jakubowski, D. Mais, 1998, Bioorganic & medicinal chemistry letters.

Synthesis of benzimidazoles from 1,1-dibromoethenes

W. Shen, Sujen Lai, Z. Fu, 2008 .

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators.

P. Coward, Jaehyeon Park, M. Véniant, 2014, ACS medicinal chemistry letters.

Stereoselectivity in the Wittig reaction of phenyl 3-pyridyl ketones: Amide substituent effect on the preferential (E)-ollefin formation

K. Takeuchi, T. Kohn, 1998 .

Stereoselectivity in the Wittig Reaction of Phenyl 3‐Pyridyl Ketones: Amide Substituent Effect on the Preferential (E)‐Olefin Formation.

K. Takeuchi, T. Kohn, 1998 .

Dibasic benzo[B]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 4. SAR studies on the conformationally restricted C3-side chain of hydroxybenzo[B]thiophenes.

K. Takeuchi, J. Mccowan, D. Gifford-Moore, 1999, Bioorganic & medicinal chemistry letters.

5-Alkyl-2-urea-Substituted Pyridines: Identification of Efficacious Glucokinase Activators with Improved Properties

P. Coward, M. Véniant, J. Medina, 2016, ACS medicinal chemistry letters.

Discovery of the imidazole-derived GPR40 agonist AM-3189.

Rajiv Sharma, Zhihua Ma, G. Tonn, 2016, Bioorganic & medicinal chemistry letters.

Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists.

Sean P. Brown, J. Medina, Thanhvien Tran, 2014, ACS medicinal chemistry letters.

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.

D. Wong, K. Takeuchi, D. Nelson, 2003, Bioorganic & medicinal chemistry letters.

Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.

D. Wong, L. Hertel, K. Takeuchi, 2003, Bioorganic & medicinal chemistry letters.

Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists.

Sean P. Brown, J. Medina, Thanhvien Tran, 2014, ACS medicinal chemistry letters.

Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of in vivo efficacy.

R. W. Harper, A. Smith, N. Chirgadze, 1999, Bioorganic & medicinal chemistry letters.

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators.

P. Coward, Jaehyeon Park, M. Véniant, 2014, ACS medicinal chemistry letters.