Shung C. Wu

发表

Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency.

L. Hamann, R. Seethala, A. Nayeem, 2007, Biochimica et biophysica acta.

Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists.

Weiqi Wang, A. Doweyko, T. Harrity, 2015, Bioorganic & medicinal chemistry letters.

Discovery of pyridyl sulfonamide 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the treatment of metabolic disorders.

L. Hamann, R. Seethala, A. Nayeem, 2014, Bioorganic & medicinal chemistry letters.

Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1).

S. Sheriff, R. Seethala, A. Nayeem, 2011, Bioorganic & medicinal chemistry letters.

Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.

D. Cheney, S. Sheriff, E. Liu, 2013, Bioorganic & medicinal chemistry letters.

Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1.

M. Kirby, Saleem Ahmad, G. Chandrasena, 2004, Bioorganic & medicinal chemistry letters.

Identification of a series of potent telomerase inhibitors using a time‐resolved fluorescence‐based assay

J. Devlin, L. Bare, L. Trinh, 1998 .

Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.

D. Davey, K. Eagen, M. Morrissey, 2003, Bioorganic & medicinal chemistry letters.

Derives d'acide utiles comme inhibiteurs de serines proteases

Shung C. Wu, Daniel L. Cheney, U. Treuner, 2001 .

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Bin Ye, David Light, Marc Adler, 2007, Journal of medicinal chemistry.

Design, synthesis, and biological activity of novel factor Xa inhibitors: 4-aryloxy substituents of 2,6-diphenoxypyridines.

K. Eagen, M. Morrissey, G. Phillips, 2002, Bioorganic & medicinal chemistry.

Free Radical Cyclizations in Alkaloid Total Synthesis: (±)-21-Oxogelsemine and (±)-Gelsemine

D. Hart, Joong-Kwon Choi, D. Ha, 1997 .

Intramolecular addition of aryl radicals to vinylogous urethanes: studies toward preparation of the oxindole portion of gelsemine

D. Hart, Shung C. Wu, 1991 .

α-Acylamino radical cyclizations: application to the synthesis of a tetracyclic substructure of gelsemine

D. Hart, Joong-Kwon Choi, D. Ha, 1989 .

Stereoselective intramolecular cyclopropanations: Enantioselective syntheses of 1α,25-dihydroxyvitamin D3 A-ring precursors

W. G. Dauben, M. Luzzio, Xiaoming Zhang, 1995 .

Photochemical synthesis of C/D-ring synthons of vitamin D

W. G. Dauben, Shung C. Wu, R. Ollmann, 1994 .

Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.

David K. Leahy, J. Barrish, M. Kirby, 2017, Journal of medicinal chemistry.

2,5-Bis-(sulfonyl)pyrazines as unprecedented building blocks and their SNAr reactions

J. Li, P. Cheng, Yong-Jin Wu, 2013 .

Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1).

S. Sheriff, R. Seethala, A. Nayeem, 2018, ACS medicinal chemistry letters.

Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Akbar Nayeem, Haixia Wang, Steven Sheriff, 2008, Bioorganic & medicinal chemistry letters.

Total Synthesis of dl-21-Oxogelsemine

D. Hart, Joong-Kwon Choi, D. Ha, 1994 .

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa.

M. Whitlow, D. Davey, K. Eagen, 1998, Journal of medicinal chemistry.