James J. Li

发表

Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency.

L. Hamann, R. Seethala, A. Nayeem, 2007, Biochimica et biophysica acta.

Discovery of a potent and novel motilin agonist.

R. Stoffel, Huabin Sun, R. Seethala, 2004, Journal of medicinal chemistry.

Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).

D. J. Garland, E. Reinhard, D. Reitz, 2005, Journal of medicinal chemistry.

Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1).

D. J. Garland, E. Reinhard, D. Reitz, 2005, Journal of medicinal chemistry.

Tetrazole based amides as growth hormone secretagogues.

R. Seethala, G. Grover, P. Sleph, 2008, Bioorganic & medicinal chemistry letters.

Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues.

R. Stoffel, K. Dickinson, R. Seethala, 2005, Bioorganic & medicinal chemistry letters.

Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain.

W. Humphreys, K. Dickinson, R. Seethala, 2008, Bioorganic & medicinal chemistry letters.

Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180).

W. Humphreys, K. Dickinson, R. Seethala, 2007, Journal of medicinal chemistry.

A synthesis of N-bridged 5,6-bicylic pyridines via a mild cyclodehydration using the burgess reagent and discovery of a novel carbamylsulfonylation reaction.

Jun Li, J. Li, H. Wong, 2008, Organic letters.

The N-Boc Group as an Activator for the a-Lithiation of Carbamates: Synthesis of 11-Substituted Dibenzoxazepines

J. Collins, D. J. Garland, M. B. Norton, 1994 .

Transition Structure Geometries for Transfers of Neutral and Anionic Nitrogen to Lithiated Carbanions.

P. Beak, James J. Li, K. Basu, 1999, The Journal of organic chemistry.

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

Dong Cheng, Ramesh Padmanabha, Kristen Pike, 2007, Bioorganic & medicinal chemistry letters.

Characterization of Agonist-Induced Motilin Receptor Trafficking and Its Implications for Tachyphylaxis

R. Seethala, D. Gordon, Zhengping Ma, 2006, Molecular Pharmacology.

Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications.

Haixia Wang, Stanley R Krystek, Jacek Ostrowski, 2007, Journal of medicinal chemistry.

Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.

David K. Leahy, J. Barrish, M. Kirby, 2017, Journal of medicinal chemistry.

Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1).

S. Sheriff, R. Seethala, A. Nayeem, 2014, ACS Medicinal Chemistry Letters.

Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).

L. Hamann, R. Seethala, D. Gordon, 2011, Bioorganic & medicinal chemistry letters.

Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1).

S. Sheriff, R. Seethala, A. Nayeem, 2018, ACS medicinal chemistry letters.

Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Akbar Nayeem, Haixia Wang, Steven Sheriff, 2008, Bioorganic & medicinal chemistry letters.

Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).

L. Hamann, R. Seethala, D. Gordon, 2011, Bioorganic & medicinal chemistry letters.

SELECTIVE CYCLOOXYGENASE INHIBITORS : NOVEL 4-SPIRO 1,2-DIARYLCYCLOPENTENES ARE POTENT AND ORALLY ACTIVE COX-2 INHIBITORS

C. Koboldt, K. Seibert, P. Isakson, 1995 .