Kristopher W King

Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo.

I. Enyedy, Janaky Coomaraswamy, J. Jones, 2021, Journal of medicinal chemistry.

Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites

J. A. Joyce, D. Rabah, Jaclyn L Henderson, 2020, PloS one.

Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors.

I. Enyedy, J. Jones, J. Santoro, 2020, ACS medicinal chemistry letters.

Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.

M. Mingueneau, J. Lyssikatos, T. Bohnert, 2021, Journal of medicinal chemistry.

Rational Design and Optimization of a Novel Class of Macrocyclic ASK1 Inhibitors.

I. Enyedy, J. Jones, Joshua L. Johnson, 2019, Journal of medicinal chemistry.