Marta Cascante

发表

Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: an example from HT29 cancer cells

Vitaly A. Selivanov, Ludmilla E. Meshalkina, Olga N. Solovjeva, 2005, Bioinform..

A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease

Josep Roca, Francesco Falciani, Stuart Egginton, 2011, PLoS Comput. Biol..

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data

Eric Fanchon, Vitaly A. Selivanov, Marta Cascante, 2016, PLoS Comput. Biol..

Interoperable and scalable metabolomics data analysis with microservices

Ola Spjuth, Christoph Steinbeck, Namrata Kale, 2017, bioRxiv.

PhenoMeNal: Processing and analysis of Metabolomics data in the Cloud

Ola Spjuth, Christoph Steinbeck, David Johnson, 2018 .

Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes

Michael Binns, Anestis Vlysidis, Constantinos Theodoropoulos, 2015, BMC Bioinformatics.

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective

Daniela Besozzi, Marija Cvijovic, Anders Blomberg, 2016, npj Systems Biology and Applications.

Molecular mechanisms underlying COPD-muscle dysfunction unveiled through a systems medicine approach

Josep Roca, Eric Fanchon, Marta Cascante, 2016, Bioinform..

Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).

Oliver Fiehn, Michael A. Schmidt, Marta Cascante, 2018, Clinical chemistry.

Creating a Bridge between Modelica and the Systems Biology Community

Daniel Hedberg, Marta Cascante, Vitaly A. Selivanov, 2009 .

Do elementary flux modes combine linearly at the "atomic" level? Integrating tracer-based metabolomics data and elementary flux modes

Angel Rubio, Francisco J. Planes, Jon Pey, 2011, Biosyst..

Model-driven discovery of long-chain fatty acid metabolic reprogramming in heterogeneous prostate cancer cells

Marta Cascante, Balázs Papp, Silvia Marin, 2018, PLoS Comput. Biol..

Reactive Oxygen Species Production by Forward and Reverse Electron Fluxes in the Mitochondrial Respiratory Chain

Josep Roca, Vitaly A. Selivanov, Marta Cascante, 2011, PLoS Comput. Biol..

Multicriteria optimization of biochemical systems by linear programming: application to production of ethanol by Saccharomyces cerevisiae.

Marta Cascante, Pedro de Atauri, Julio Vera, 2003, Biotechnology and bioengineering.

What makes biochemical networks tick?

Hans V Westerhoff, Marta Cascante, Boris N Goldstein, 2004, European journal of biochemistry.

ChainRank, a chain prioritisation method for contextualisation of biological networks

David Gomez-Cabrero, Francesco Falciani, Isaac Cano, 2016, BMC Bioinformatics.

Software for dynamic analysis of tracer-based metabolomic data: estimation of metabolic fluxes and their statistical analysis

Vitaly A. Selivanov, Paul W.-N. Lee, Marta Cascante, 2006, Bioinform..

Metabolomics in systems medicine: an overview of methods and applications

Edoardo Saccenti, Vitor A. P. Martins dos Santos, Marta Cascante, 2019, Current Opinion in Systems Biology.

Edelfosine-induced metabolic changes in cancer cells that precede the overproduction of reactive oxygen species and apoptosis

Vitaly A. Selivanov, Paul W.-N. Lee, Marta Cascante, 2010, BMC Systems Biology.

Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis

Mark Friedman, Vitaly A. Selivanov, Marta Cascante, 2012, PLoS Comput. Biol..

Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions

Matej Oresic, Josep Roca, Vitaly A. Selivanov, 2011, BMC Systems Biology.

ASSESSING OPTIMAL DESIGNS IN METABOLIC PATHWAYS

Albert Sorribas, Marta Cascante, J. Puigjaner, 1995 .

An optimized algorithm for flux estimation from isotopomer distribution in glucose metabolites

Vitaly A. Selivanov, Antonio Ramos-Montoya, Paul W.-N. Lee, 2004, Bioinform..

Knowledge management for systems biology a general and visually driven framework applied to translational medicine

Jordi Villà-Freixa, Francesco Falciani, Dieter Maier, 2011, BMC Systems Biology.

Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia

Josep Roca, Vitaly A. Selivanov, Marta Cascante, 2009, PLoS Comput. Biol..

Detection of potential enzyme targets by metabolic modelling and optimization: Application to a simple enzymopathy

Julio Vera, Marta Cascante, Néstor V. Torres, 2007, Bioinform..

Steady-State Measurements and Identifiability of Regulatory Patterns in Metabolic Studies

Albert Sorribas, Marta Cascante, M. Cascante, 1993 .

13C metabolic flux analysis shows that resistin impairs the metabolic response to insulin in L6E9 myotubes

Vitaly A. Selivanov, Marta Cascante, Silvia Marin, 2014, BMC Systems Biology.

MIDcor, an R-program for deciphering mass interferences in mass spectra of metabolites enriched in stable isotopes

Vitaly A. Selivanov, Paul W.-N. Lee, Marta Cascante, 2017, BMC Bioinformatics.

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

Matej Oresic, Christoph Steinbeck, Dirk Walther, 2015, Metabolomics.

p13CMFA: Parsimonious 13C metabolic flux analysis

Pablo Moreno, Marta Cascante, Carles Foguet, 2019, PLoS Comput. Biol..

New insights into metabolic pathway optimization by analogy with industrial manufacturing processes

Fernando Ortega, Marta Cascante, Fernando Ortega, 1999 .

Interoperable and scalable data analysis with microservices: Applications in Metabolomics

Ola Spjuth, Christoph Steinbeck, Namrata Kale, 2018 .

Interoperable and scalable data analysis with microservices: applications in metabolomics

Ola Spjuth, Christoph Steinbeck, David Johnson, 2019, Bioinform..

From correlation to causation: analysis of metabolomics data using systems biology approaches

Antonio Rosato, Edoardo Saccenti, Marta Cascante, 2018, Metabolomics.

Mathematica Notebooks supporting "Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations"

Marta Cascante, Carles Foguet, Pedro de Atauri, 2021 .

The puzzle of the Krebs citric acid cycle: Assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution

Marta Cascante, Thomas G. Waddell, M. Cascante, 1996, Journal of Molecular Evolution.

Predictive medicine: outcomes, challenges and opportunities in the Synergy-COPD project

Jesper Tegnér, David Gomez-Cabrero, Josep Roca, 2014, Journal of Translational Medicine.

Bistability from double phosphorylation in signal transduction

Marta Cascante, Fernando Ortega, Boris N Kholodenko, 2006, The FEBS journal.

Systems Medicine: from molecular features and models to the clinic in COPD

Jesper Tegnér, Albert-László Barabási, Francesco Marabita, 2014, Journal of Translational Medicine.

Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose.

Marta Cascante, Wai-Nang Paul Lee, Joaquim Puigjaner, 1998, American journal of physiology. Endocrinology and metabolism.

Effect of crowding by Dextrans in enzymatic reactions.

Laura Pitulice, Sergio Madurga, Marta Cascante, 2014, Biophysical chemistry.

The Role of External and Matrix pH in Mitochondrial Reactive Oxygen Species Generation*

Josep Roca, Vitaly A. Selivanov, Marta Cascante, 2008, Journal of Biological Chemistry.

Muscle and blood redox status after exercise training in severe COPD patients.

Josep Roca, Francesco Falciani, Marta Cascante, 2012, Free radical biology & medicine.

Mathematical Modeling of Polyamine Metabolism in Mammals*

Marta Cascante, M. Cascante, C. Rodríguez-Caso, 2006, Journal of Biological Chemistry.

Biomedical research in a Digital Health Framework

Jesper Tegnér, David Gomez-Cabrero, Josep Roca, 2014, Journal of Translational Medicine.

In silico strategy to rationally engineer metabolite production: A case study for threonine in Escherichia coli

Jean-Charles Portais, Marta Cascante, Fernando Ortega, 2009, Biotechnology and bioengineering.

Characterization of the transit and transition times for a pathway unit of Michaelis-Menten mechanism.

Marta Cascante, Pedro de Atauri, M. Cascante, 2003, Biochimica et biophysica acta.

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

Daniel Rico, Marta Cascante, M. Cascante, 2010, The Journal of Immunology.

Diphenyl Urea Derivatives as Inhibitors of Transketolase: A Structure-Based Virtual Screening

Jaime Rubio-Martinez, Marta Cascante, Cristian Obiol-Pardo, 2012, PloS one.

Effect of several anions on the activity of mitochondrial malate dehydrogenase from pig heart

Marta Cascante, Josep Ll. Gelpí, Ana Ruggia, 2001 .

Mathematical modelling of the urea cycle. A numerical investigation into substrate channelling.

Marta Cascante, Fernando Ortega, Pedro de Atauri, 2003, European journal of biochemistry.

Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29

Marta Cascante, Pedro Vizán, M. Cascante, 2009, International journal of cancer.

Modeling of spatial metabolite distributions in the cardiac sarcomere.

Josep Roca, Marta Cascante, M. Cascante, 2007, Biophysical journal.

The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research

David Gomez-Cabrero, Josep Roca, Francesco Falciani, 2014, Journal of Translational Medicine.

Tracing metabolic fluxes using mass spectrometry: Stable isotope-resolved metabolomics in health and disease

Marta Cascante, Carles Foguet, Silvia Marin, 2019, TrAC Trends in Analytical Chemistry.

Chronic Obstructive Pulmonary Disease heterogeneity: challenges for health risk assessment, stratification and management

Jesper Tegnér, David Gomez-Cabrero, Josep Roca, 2014, Journal of Translational Medicine.

Use of metabolic pathway flux information in targeted cancer drug design

Marta Cascante, Wai-Nang Paul Lee, M. Cascante, 2004 .

Use of alpha-toxin from Staphylococcus aureus to test for channelling of intermediates of glycolysis between glucokinase and aldolase in hepatocytes.

Marta Cascante, Loranne Agius, Josep J. Centelles, 2000 .

Practical Determination of Control Coefficients in Metabolic Pathways

Marta Cascante, Rafael Franco, Enric I. Canela, 1990 .

TESTING THE ROBUSTNESS OF THE STEADY-STATE CHARACTERISTICS OF A METABOLIC PATHWAY: PARAMETER SENSITIVITIES AS A BASIC FEATURE FOR MODEL VALIDATION

Albert Sorribas, Marta Cascante, Raul Curto, 1995 .

Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose.

Marta Cascante, Silvia Marin, Josep J Centelles, 2004, The Biochemical journal.

K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts.

Marta Cascante, Ramon Mangues, M. Cascante, 2005, Cancer research.

Effects of Cadmium and Mercury on the Upper Part of Skeletal Muscle Glycolysis in Mice

Hans V. Westerhoff, Josep Lluis Gelpí, Marta Cascante, 2014, PloS one.

Workforce preparation: the Biohealth computing model for Master and PhD students

David Gomez-Cabrero, Josep Roca, Isaac Cano, 2014, Journal of Translational Medicine.

Metabolic network adaptations in cancer as targets for novel therapies.

Marta Cascante, Pedro de Atauri, Pedro Vizán, 2010, Biochemical Society transactions.

Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.

Marta Cascante, Wai-Nang Paul Lee, Pedro Vizán, 2009, Carcinogenesis.

Targeting cell cycle regulation in cancer therapy.

Marta Cascante, Anibal Miranda, Míriam Tarrado-Castellarnau, 2013, Pharmacology & therapeutics.

Metabolomics and fluxomics approaches.

Marta Cascante, Silvia Marin, M. Cascante, 2008, Essays in biochemistry.

Oxygen Pathway Modeling Estimates High Reactive Oxygen Species Production above the Highest Permanent Human Habitation

Jesper Tegnér, David Gomez-Cabrero, Josep Roca, 2014, PloS one.

Metabolomics enables precision medicine: “A White Paper, Community Perspective”

Matej Oresic, David S. Wishart, Richard D. Beger, 2016, Metabolomics.

Metabolic profiling of cell growth and death in cancer: applications in drug discovery.

Marta Cascante, M. Cascante, L. Boros, 2002, Drug discovery today.

Assessment of the regulatory properties of a metabolic pathway: parameter estimation from steady-state measurements

Albert Sorribas, Marta Cascante, 1995 .

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.

Olaf Wolkenhauer, Nils Blüthgen, Charles Auffray, 2010, Cancer research.

The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism

Marta Cascante, Fernando J. Reyes-Zurita, M. Cascante, 2011, BMC Cancer.

Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer

Marta Cascante, M. Cascante, J. Centelles, 2006, International journal of cancer.

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

Matej Oresic, Christoph Steinbeck, Dirk Walther, 2015, Metabolomics.

K-ras Codon-Specific Mutations Produce Distinctive Metabolic Phenotypes in Human Fibroblasts

Marta Cascante, Gabriel Capellá, Ramon Mangues, 2005 .

Pentose phosphate and calvin cycles: Similarities and three‐dimensional views *

Marta Cascante, Antonio Sillero, M. Cascante, 2006, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology.