Nils Wiedemann

发表

Import of proteins into mitochondria.

N. Pfanner, D. Stojanovski, Nils Wiedemann, 1988, Methods in cell biology.

Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.

F. Metzger, O. Kretz, C. Graff, 2014, Cell metabolism.

Composition and topology of the endoplasmic reticulum-mitochondria encounter structure.

Albert Sickmann, Bettina Warscheid, Sebastian Wiese, 2011, Journal of molecular biology.

Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10

N. Pfanner, T. Becker, E. Schleiff, 2016, Nature Communications.

The morphology proteins Mdm12/Mmm1 function in the major β‐barrel assembly pathway of mitochondria

N. Pfanner, T. Becker, D. Stojanovski, 2007, The EMBO journal.

Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain

N. Pfanner, P. Rehling, M. van der Laan, 2007, The Journal of cell biology.

Biogenesis of yeast mitochondrial cytochrome c: a unique relationship to the TOM machinery.

N. Pfanner, C. Meisinger, K. Truscott, 2003, Journal of molecular biology.

Assembling the Outer Membrane

N. Pfanner, C. Meisinger, D. Stroud, 2010, Science.

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

P. Schanda, J. Martinou, N. Pfanner, 2020, BMC Biology.

Processing and Topology of the Yeast Mitochondrial Phosphatidylserine Decarboxylase 1*

T. Becker, G. Daum, C. Meisinger, 2012, The Journal of Biological Chemistry.

Sam37 is crucial for formation of the mitochondrial TOM–SAM supercomplex, thereby promoting β-barrel biogenesis

N. Pfanner, M. van der Laan, T. Becker, 2015, The Journal of cell biology.

Retro-translocation of mitochondrial intermembrane space proteins

A. Chacińska, Paulina Sakowska, Jian Qiu, 2015, Proceedings of the National Academy of Sciences.

Distinct Forms of Mitochondrial TOM-TIM Supercomplexes Deﬁne Signal-Dependent States of Preprotein Sorting (cid:1)

N. Pfanner, P. Rehling, C. Meisinger, 2009 .

The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins.

N. Pfanner, K. Gabriel, B. Guiard, 2005, Journal of molecular biology.

Assembling the mitochondrial outer membrane

Trevor Lithgow, T. Lithgow, N. Pfanner, 2004, Nature Structural &Molecular Biology.

Response: The Mitochondrial β-Signal and Protein Sorting

Stephan Kutik, N. Pfanner, T. Becker, 2008, Cell.

Double Membrane Fusion

N. Pfanner, C. Meisinger, Nils Wiedemann, 2004, Science.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

C. Kraft, N. Pfanner, F. Drepper, 2021, Cell metabolism.

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

M. Schuldiner, N. Pfanner, F. Drepper, 2017, Cell reports.

Heat Stress-Induced Metabolic Remodeling in Saccharomyces cerevisiae

B. Kammerer, Nils Wiedemann, Daqiang Pan, 2019, Metabolites.

The mitochondrial protein import machinery has multiple connections to the respiratory chain.

B. Guiard, N. Wiedemann, Michael Gebert, 2013, Biochimica et biophysica acta.

The Protein Import Machinery of Mitochondria*

N. Pfanner, Ann E. Frazier, Nils Wiedemann, 2004, Journal of Biological Chemistry.

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

K. Lindorff-Larsen, B. Schönfisch, P. Schanda, 2018, Cell.

Universitet Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane

K. Lindorff-Larsen, B. Schönfisch, P. Schanda, 2018 .

Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis.

Katrin Marcus, Martin van der Laan, Christiane Lohaus, 2005, Journal of molecular biology.

Structure of the mitochondrial import gate reveals distinct preprotein paths

T. Ando, T. Lithgow, N. Pfanner, 2019, Nature.

Mitochondrial Machineries for Protein Import and Assembly.

N. Pfanner, N. Wiedemann, Nils Wiedemann, 2017, Annual review of biochemistry.

Lam6 Regulates the Extent of Contacts between Organelles

M. Schuldiner, T. Geiger, E. Shimoni, 2015, Cell reports.

Respiratory chain supercomplexes associate with the cysteine desulfurase complex of the iron–sulfur cluster assembly machinery

T. Becker, N. Zufall, L. Böttinger, 2018, Molecular biology of the cell.

Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins

N. Pfanner, S. Oeljeklaus, B. Warscheid, 2016, Cell metabolism.

Membrane protein insertion through a mitochondrial β-barrel gate

Stephan Kutik, N. Pfanner, T. Becker, 2018, Science.

Mitochondrial proteins: from biogenesis to functional networks

N. Pfanner, B. Warscheid, N. Wiedemann, 2019, Nature Reviews Molecular Cell Biology.

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

Matthias Meurer, Michael Knop, Maya Schuldiner, 2016, Nature Methods.

The Mitochondrial Import Machinery for Preproteins

N. Pfanner, P. Rehling, N. Wiedemann, 2001, Critical reviews in biochemistry and molecular biology.

Mitochondrial proteins: from biogenesis to functional networks

N. Pfanner, B. Warscheid, Nils Wiedemann, 2019, Nature Reviews Molecular Cell Biology.

Role of MINOS in mitochondrial membrane architecture and biogenesis.

Martin van der Laan, N. Pfanner, M. van der Laan, 2012, Trends in cell biology.

Mitochondrial Protein Sorting

B. Schönfisch, N. Pfanner, C. Meisinger, 2006, Journal of Biological Chemistry.

Biogenesis of the Protein Import Channel Tom40 of the Mitochondrial Outer Membrane

N. Pfanner, C. Meisinger, B. Guiard, 2004, Journal of Biological Chemistry.

Complete Native Stable Isotope Labeling by Amino Acids of Saccharomyces cerevisiae for Global Proteomic Analysis

S. Oeljeklaus, B. Warscheid, Marcel Morgenstern, 2018, Analytical chemistry.

A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase

S. Oeljeklaus, B. Warscheid, M. van der Laan, 2013, Molecular biology of the cell.

The Assembly Pathway of the Mitochondrial Carrier Translocase Involves Four Preprotein Translocases

N. Pfanner, P. Rehling, B. Guiard, 2008, Molecular and Cellular Biology.

Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

Stephan Kutik, N. Pfanner, P. Rehling, 2009, Current Biology.

Biallelic variants in HPDL, encoding 4-hydroxyphenylpyruvate dioxygenase-like protein, lead to an infantile neurodegenerative condition

Mohit M. Jain, R. Maroofian, J. Gleeson, 2020, Genetics in Medicine.

A multipoint guidance mechanism for β-barrel folding on the SAM complex

T. Hirokawa, C. Motono, K. Tomii, 2023, Nature Structural & Molecular Biology.

The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

N. Pfanner, M. Ryan, M T Ryan, 2001, The EMBO journal.

The Mitochondrial Presequence Translocase An Essential Role of Tim50 in Directing Preproteins to the Import Channel

N. Pfanner, A. Sickmann, P. Rehling, 2002, Cell.

The protein import machinery of mitochondria

N. Pfanner, N. Wiedemann, Ann E. Frazier, 2007 .

Sam35 of the Mitochondrial Protein Sorting and Assembly Machinery Is a Peripheral Outer Membrane Protein Essential for Cell Viability*

N. Pfanner, C. Meisinger, B. Guiard, 2004, Journal of Biological Chemistry.

Machinery for protein sorting and assembly in the mitochondrial outer membrane

B. Schönfisch, N. Pfanner, C. Meisinger, 2003, Nature.

Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses

B. Kammerer, S. Lagies, Caroline Lindau, 2018, Metabolomics.

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane

Bettina Warscheid, Thomas Becker, Silke Oeljeklaus, 2012, Molecular biology of the cell.

Distinct Forms of Mitochondrial TOM-TIM Supercomplexes Define Signal-Dependent States of Preprotein Sorting

N. Pfanner, P. Rehling, M. van der Laan, 2009, Molecular and Cellular Biology.

Cooperation of protein machineries in mitochondrial protein sorting.

T. Becker, Łukasz Opaliński, Nils Wiedemann, 2015, Biochimica et biophysica acta.

An Essential Role of Sam50 in the Protein Sorting and Assembly Machinery of the Mitochondrial Outer Membrane*

N. Pfanner, C. Meisinger, B. Guiard, 2003, Journal of Biological Chemistry.

Dynamic organization of the mitochondrial protein import machinery

N. Pfanner, Sebastian B. Stiller, Nils Wiedemann, 2016, Biological chemistry.

Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains.

Bettina Warscheid, Thomas Becker, Silke Oeljeklaus, 2012, Journal of molecular biology.

Assembly of β-barrel proteins in the mitochondrial outer membrane.

B. Warscheid, T. Becker, Nils Wiedemann, 2015, Biochimica et biophysica acta.

Biogenesis of the Mitochondrial TOM Complex Mim1 PROMOTES INSERTION AND ASSEMBLY OF SIGNAL-ANCHORED RECEPTORS*

Stephan Kutik, N. Pfanner, T. Becker, 2007 .

Identification of new channels by systematic analysis of the mitochondrial outer membrane

N. Pfanner, B. Warscheid, T. Becker, 2017, The Journal of cell biology.

Dual Function of Sdh 3 in the Respiratory Chain and TIM 22 Protein Translocase of the Mitochondrial Inner Membrane

N. Pfanner, R. Zahedi, A. Sickmann, 2017 .

Molecular architecture of the active mitochondrial protein gate

Arne Elofsson, Paul Horton, Kenichiro Imai, 2015, Science.

Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.

N. Pfanner, R. Zahedi, A. Sickmann, 2011, Molecular cell.

Biogenesis of mitochondria: dual role of Tom7 in modulating assembly of the preprotein translocase of the outer membrane.

N. Pfanner, T. Becker, C. Meisinger, 2011, Journal of molecular biology.

A Role for Tim21 in Membrane-Potential-Dependent Preprotein Sorting in Mitochondria

N. Pfanner, P. Rehling, B. Guiard, 2006, Current Biology.

Evolution of mitochondrial protein biogenesis.

Stephan Kutik, N. Pfanner, D. Stroud, 2009, Biochimica et biophysica acta.

Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

Thomas Becker, Stephan Kutik, N. Pfanner, 2008, Cell.

Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins

N. Pfanner, C. Meisinger, B. Guiard, 2004, The EMBO journal.

Mitochondrial protein import: two membranes, three translocases.

N. Pfanner, Nils Wiedemann, 2002, Current opinion in cell biology.

Mitochondrial protein transport: Versatility of translocases and mechanisms.

N. Pfanner, Jakob D Busch, L. Fielden, 2023, Molecular cell.

Essential role of Isd11 in mitochondrial iron–sulfur cluster synthesis on Isu scaffold proteins

N. Pfanner, C. Meisinger, B. Guiard, 2006, The EMBO journal.

Mitochondrial sorting and assembly machinery operates by β-barrel switching

O. Nureki, K. Tomii, T. Nishizawa, 2021, Nature.

Mitochondrial sorting and assembly machinery operates by β-barrel switching

O. Nureki, K. Tomii, T. Nishizawa, 2021, Nature.

Biogenesis and folding of β-barrel membrane proteins

T. Becker, N. Wiedemann, L. Wenz, 2013, Cell cycle.

Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex

N. Pfanner, T. Becker, C. Hunte, 2011, Molecular biology of the cell.

Mitochondrial protein import machineries and lipids: a functional connection.

N. Pfanner, D. Stojanovski, N. Wiedemann, 2011, Biochimica et biophysica acta.

Role of the small protein Mco6 in the mitochondrial sorting and assembly machinery

B. Fakler, T. Becker, B. Guiard, 2023, bioRxiv.

Coupling of Mitochondrial Import and Export Translocases by Receptor-Mediated Supercomplex Formation

Stephan Kutik, N. Pfanner, S. Oeljeklaus, 2013, Cell.

Assembly of the Mitochondrial Protein Import Channel

N. Pfanner, T. Becker, B. Guiard, 2010, Molecular biology of the cell.

SnapShot: Import and Sortingof Mitochondrial Proteins

N. Pfanner, Nils Wiedemann, M. Laan, 2009, Cell.

Report olved in Outer-Membrane Protein Biogenesis : Implications for Barth Syndrome

Stephan Kutik, N. Pfanner, P. Rehling, 2009 .

Multistep assembly of the protein import channel of the mitochondrial outer membrane

N. Pfanner, C. Meisinger, N. Wiedemann, 2001, Nature Structural Biology.

The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane.

Christiane Lohaus, B. Schönfisch, N. Pfanner, 2004, Developmental cell.

Cooperation of translocase complexes in mitochondrial protein import

Helmut E. Meyer, Stephan Kutik, N. Pfanner, 2007, The Journal of cell biology.

Chaperoning through the mitochondrial intermembrane space.

N. Pfanner, A. Chacińska, Nils Wiedemann, 2006, Molecular cell.

The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1

M. van der Laan, M. Wenk, X. Guan, 2015, The Journal of cell biology.

Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase

N. Pfanner, P. Rehling, B. Guiard, 2008, EMBO reports.

The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis

Stephan Kutik, N. Pfanner, P. Rehling, 2008, The Journal of cell biology.

Biogenesis of the Mitochondrial TOM Complex

Stephan Kutik, N. Pfanner, T. Becker, 2008, Journal of Biological Chemistry.

Mitochondrial complexome reveals quality-control pathways of protein import

B. Fakler, N. Pfanner, T. Becker, 2023, Nature.

Connecting Organelles

N. Pfanner, C. Meisinger, Nils Wiedemann, 2009, Science.

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.

N. Pfanner, M. van der Laan, Jingzhi Li, 2011, Journal of molecular biology.

The presequence pathway is involved in protein sorting to the mitochondrial outer membrane

N. Pfanner, T. Becker, B. Guiard, 2014, EMBO reports.

Molecular architecture of active preprotein transloca tor of mitochondria

A. Elofsson, T. Lithgow, K. Tomii, 2015 .

Import of precursor proteins into isolated yeast mitochondria.

N. Pfanner, P. Rehling, Nils Wiedemann, 2006, Methods in molecular biology.

The Channel-Forming Sym1 Protein Is Transported by the TIM23 Complex in a Presequence-Independent Manner

Jan Dudek, P. Rehling, M. van der Laan, 2012, Molecular and Cellular Biology.

Mitochondrial Import of the ADP/ATP Carrier: the Essential TIM Complex of the Intermembrane Space Is Required for Precursor Release from the TOM Complex

N. Pfanner, P. Rehling, C. Meisinger, 2002, Molecular and Cellular Biology.

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism

C. Montell, J. Adamski, G. Walz, 2018, PLoS biology.

Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation.

N. Pfanner, Sebastian B. Stiller, Nils Wiedemann, 2013, Molecular cell.

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

P. Schanda, J. Martinou, N. Pfanner, 2020, BMC Biology.

One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy

M. Schuldiner, E. Zalckvar, S. Ben-Dor, 2016, Nature methods.