T. Okuno

发表

Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy.

Y. Tonomura, A. Ino, S. Sakamoto, 2018, Bioorganic & medicinal chemistry letters.

Discovery of a benzimidazole series as the first highly potent and selective ACSL1 inhibitors.

R. Yoshimoto, K. Hayashi, Shuhei Shigaki, 2020, Bioorganic & medicinal chemistry letters.

Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'.

Katsutoshi Yamada, T. Ono, K. Yamada, 2001, Bioorganic & medicinal chemistry letters.

A novel RORγt inhibitor is a potential therapeutic agent for the topical treatment of psoriasis with low risk of thymic aberrations.

K. Yasui, K. Katayama, A. Ueyama, 2019, Journal of dermatological science.

Characterization of a novel inhibitor of cytosolic phospholipase A2alpha, pyrrophenone.

Katsutoshi Yamada, T. Ono, M. Ueno, 2002, The Biochemical journal.

A Stereoselective and Highly Practical Synthesis of Cytosolic Phospholipase A2 Substrate, 2‐S‐Arachidonoyl‐1‐O‐hexadecyl‐sn‐2‐thioglycero‐3‐O‐phosphocholine.

H. Hashizume, Y. Fujii, M. Fuji, 1998 .

A STEREOSELECTIVE AND HIGHLY PRACTICAL SYNTHESIS OF CYTOSOLIC PHOSPHOLIPASE A2 SUBSTRATE, 2-S-ARACHIDONOYL-1-O-HEXADECYL-SN-2-THIOGLYCERO-3-O-PHOSPHOC HOLINE

H. Hashizume, Y. Fujii, M. Fuji, 1997 .

An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice

A. Obata, H. Yukioka, H. Nambu, 2018, Neuropeptides.

Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor, S18-000003.

Shiho Yamamoto, A. Ueyama, A. Watanabe, 2018, Bioorganic & medicinal chemistry letters.

Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacy.

Yukari Tanaka, H. Yukioka, Yuji Nishiura, 2012, Bioorganic & medicinal chemistry letters.

Design, synthesis and identification of novel benzimidazole derivatives as highly potent NPY Y5 receptor antagonists with attractive in vitro ADME profiles.

Yukari Tanaka, H. Yukioka, Yuji Nishiura, 2012, Bioorganic & medicinal chemistry letters.

Pyrrolidine inhibitors of human cytosolic phospholipase A(2).

Katsutoshi Yamada, T. Okada, H. Hashizume, 2000, Journal of medicinal chemistry.

Pyrrolidine Inhibitors of Human Cytosolic Phospholipase A2. Part 2. Synthesis of Potent and Crystallized 4-Triphenylmethylthio Derivative “Pyrrophenone”.

Katsutoshi Yamada, T. Ono, Y. Murakami, 2001 .

Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist.

Yukari Tanaka, Y. Yokota, H. Yukioka, 2012, Bioorganic & medicinal chemistry letters.

Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile.

Yukari Tanaka, H. Yukioka, H. Nambu, 2013, Bioorganic & medicinal chemistry letters.