Jing Li

Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers.

Lihong Hu, A. L. Risinger, S. Mooberry, 2011, Journal of the American Chemical Society.

The marine bromotyrosine derivatives.

M. Hamann, Jiangnan Peng, Jing Li, 2005, The Alkaloids. Chemistry and biology.

Taccalonolide microtubule stabilizers.

S. Mooberry, Jing Li, A. Risinger, 2014, Bioorganic & medicinal chemistry.

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

Andrew J. Robles, R. Cichewicz, L. Du, 2017, Journal of natural products.

Synthetic Reactions with Rare Taccalonolides Reveal the Value of C-22,23 Epoxidation for Microtubule Stabilizing Potency

S. Mooberry, Jiangnan Peng, Jing Li, 2014, Journal of medicinal chemistry.

Epoxidation at C22-C23 significantly increases the potency of microtubule stabilizing taccalonolides

Jiangnan Peng, Jing Li, A. Risinger, 2012 .

Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.

D. Schriemer, A. L. Risinger, S. Mooberry, 2013, Cancer research.